Page last updated: 2024-10-06

Defective homologous recombination repair (HRR) due to BRCA2 loss of function

Proteins (18)

ProteinSynonymsTaxonomy
DNA topoisomerase 2-binding protein 1DNA topoisomerase II-beta-binding protein 1; TopBP1; DNA topoisomerase II-binding protein 1Homo sapiens (human)
Fanconi anemia group J proteinProtein FACJ; EC 3.6.4.13; ATP-dependent RNA helicase BRIP1; BRCA1-associated C-terminal helicase 1; BRCA1-interacting protein C-terminal helicase 1; BRCA1-interacting protein 1Homo sapiens (human)
DNA repair protein RAD51 homolog 1HsRAD51; hRAD51; RAD51 homolog AHomo sapiens (human)
Replication factor C subunit 5Activator 1 36 kDa subunit; A1 36 kDa subunit; Activator 1 subunit 5; Replication factor C 36 kDa subunit; RF-C 36 kDa subunit; RFC36Homo sapiens (human)
Cell cycle checkpoint protein RAD1hRAD1; EC 3.1.11.2; DNA repair exonuclease rad1 homolog; Rad1-like DNA damage checkpoint proteinHomo sapiens (human)
26S proteasome complex subunit SEM126S proteasome complex subunit DSS1; Deleted in split hand/split foot protein 1; Split hand/foot deleted protein 1; Split hand/foot malformation type 1 proteinHomo sapiens (human)
DNA repair protein RAD51 homolog 2R51H2; RAD51 homolog B; Rad51B; RAD51-like protein 1Homo sapiens (human)
DNA repair protein RAD51 homolog 4R51H3; RAD51 homolog D; RAD51-like protein 3; TRADHomo sapiens (human)
DNA repair protein RAD51 homolog 3R51H3; RAD51 homolog C; RAD51-like protein 2Homo sapiens (human)
DNA repair protein XRCC2X-ray repair cross-complementing protein 2Homo sapiens (human)
Checkpoint protein HUS1hHUS1Homo sapiens (human)
Cell cycle checkpoint protein RAD17hRad17; RF-C/activator 1 homologHomo sapiens (human)
Replication factor C subunit 4Activator 1 37 kDa subunit; A1 37 kDa subunit; Activator 1 subunit 4; Replication factor C 37 kDa subunit; RF-C 37 kDa subunit; RFC37Homo sapiens (human)
Replication factor C subunit 2Activator 1 40 kDa subunit; A1 40 kDa subunit; Activator 1 subunit 2; Replication factor C 40 kDa subunit; RF-C 40 kDa subunit; RFC40Homo sapiens (human)
Replication factor C subunit 3Activator 1 38 kDa subunit; A1 38 kDa subunit; Activator 1 subunit 3; Replication factor C 38 kDa subunit; RF-C 38 kDa subunit; RFC38Homo sapiens (human)
Partner and localizer of BRCA2Homo sapiens (human)
RAD51-associated protein 1HsRAD51AP1; RAD51-interacting proteinHomo sapiens (human)
RAD9, HUS1, RAD1-interacting nuclear orphan protein 1RAD9, RAD1, HUS1-interacting nuclear orphan proteinHomo sapiens (human)

Compounds (0)

CompoundDescription