Page last updated: 2024-10-06

Deadenylation-dependent mRNA decay

Proteins (41)

ProteinSynonymsTaxonomy
Eukaryotic translation initiation factor 4EeIF-4E; eIF4E; eIF-4F 25 kDa subunit; mRNA cap-binding proteinHomo sapiens (human)
Eukaryotic translation initiation factor 4 gamma 1eIF-4-gamma 1; eIF-4G 1; eIF-4G1; p220Homo sapiens (human)
CCR4-NOT transcription complex subunit 1CCR4-associated factor 1; Negative regulator of transcription subunit 1 homolog; NOT1H; hNOT1Homo sapiens (human)
7-methylguanosine phosphate-specific 5'-nucleotidase7-methylguanosine nucleotidase; EC 3.1.3.91; Cytosolic 5'-nucleotidase 3B; Cytosolic 5'-nucleotidase III-like protein; cN-III-like protein; 3.1.3.5; N(7)-methylguanylate 5'-phosphataseHomo sapiens (human)
CCR4-NOT transcription complex subunit 9Cell differentiation protein RQCD1 homolog; Rcd-1Homo sapiens (human)
CCR4-NOT transcription complex subunit 10Homo sapiens (human)
Eukaryotic translation initiation factor 4BeIF-4BHomo sapiens (human)
m7GpppX diphosphataseEC 3.6.1.59; DCS-1; Decapping scavenger enzyme; Hint-related 7meGMP-directed hydrolase; Histidine triad nucleotide-binding protein 5; Histidine triad protein member 5; HINT-5; Scavenger mRNA-decapping enzyme DcpSHomo sapiens (human)
PolyEC 3.1.13.4; Deadenylating nuclease; Deadenylation nuclease; Polyadenylate-specific ribonucleaseHomo sapiens (human)
Tetratricopeptide repeat protein 37TPR repeat protein 37; SKI3 homolog; Ski3; Tricho-hepatic-enteric syndrome protein; ThespinHomo sapiens (human)
5'-3' exoribonuclease 1EC 3.1.13.-; Strand-exchange protein 1 homologHomo sapiens (human)
Exosome complex exonuclease RRP44EC 3.1.13.-; EC 3.1.26.-; Protein DIS3 homolog; Ribosomal RNA-processing protein 44Homo sapiens (human)
CCR4-NOT transcription complex subunit 3CCR4-associated factor 3; Leukocyte receptor cluster member 2Homo sapiens (human)
PAN2-PAN3 deadenylation complex subunit PAN3PAB1P-dependent poly(A)-specific ribonuclease; Poly(A)-nuclease deadenylation complex subunit 3; PAN deadenylation complex subunit 3Homo sapiens (human)
182 kDa tankyrase-1-binding proteinHomo sapiens (human)
CCR4-NOT transcription complex subunit 11Homo sapiens (human)
Helicase SKI2WSki2; EC 3.6.4.-; Helicase-like protein; HLPHomo sapiens (human)
WD repeat-containing protein 61Meiotic recombination REC14 protein homolog; SKI8 homolog; Ski8Homo sapiens (human)
CCR4-NOT transcription complex subunit 4EC 2.3.2.27; CCR4-associated factor 4; E3 ubiquitin-protein ligase CNOT4; Potential transcriptional repressor NOT4Hp; RING-type E3 ubiquitin transferase CNOT4Homo sapiens (human)
Probable ATP-dependent RNA helicase DDX6EC 3.6.4.13; ATP-dependent RNA helicase p54; DEAD box protein 6; Oncogene RCKHomo sapiens (human)
CCR4-NOT transcription complex subunit 2CCR4-associated factor 2Homo sapiens (human)
U6 snRNA-associated Sm-like protein LSm4Glycine-rich protein; GRPHomo sapiens (human)
Exosome complex component RRP40Exosome component 3; Ribosomal RNA-processing protein 40; p10Homo sapiens (human)
U6 snRNA-associated Sm-like protein LSm1Cancer-associated Sm-like; Small nuclear ribonuclear CaSmHomo sapiens (human)
Polyadenylate-binding protein 1PABP-1; Poly(A)-binding protein 1Homo sapiens (human)
U6 snRNA-associated Sm-like protein LSm3Homo sapiens (human)
U6 snRNA-associated Sm-like protein LSm6Homo sapiens (human)
Exosome complex component RRP4Exosome component 2; Ribosomal RNA-processing protein 4Homo sapiens (human)
PAN2-PAN3 deadenylation complex catalytic subunit PAN2EC 3.1.13.4; Inactive ubiquitin carboxyl-terminal hydrolase 52; PAB1P-dependent poly(A)-specific ribonuclease; Poly(A)-nuclease deadenylation complex subunit 2; PAN deadenylation complex subunit 2Homo sapiens (human)
Enhancer of mRNA-decapping protein 4Autoantigen Ge-1; Autoantigen RCD-8; Human enhancer of decapping large subunit; HedlsHomo sapiens (human)
Protein PAT1 homolog 1PAT1-like protein 1; Protein PAT1 homolog b; Pat1b; hPat1bHomo sapiens (human)
m7GpppN-mRNA hydrolaseEC 3.6.1.62; Nucleoside diphosphate-linked moiety X motif 20; Nudix motif 20; mRNA-decapping enzyme 2; hDpcHomo sapiens (human)
mRNA-decapping enzyme 1BEC 3.-.-.-Homo sapiens (human)
Enhancer of mRNA-decapping protein 3LSM16 homolog; YjeF N-terminal domain-containing protein 2; YjeF_N2; hYjeF_N2; YjeF domain-containing protein 1Homo sapiens (human)
Polyadenylate-binding protein-interacting protein 1PABP-interacting protein 1; PAIP-1; Poly(A)-binding protein-interacting protein 1Homo sapiens (human)
mRNA-decapping enzyme 1AEC 3.-.-.-; Smad4-interacting transcriptional co-activator; Transcription factor SMIFHomo sapiens (human)
U6 snRNA-associated Sm-like protein LSm7Homo sapiens (human)
U6 snRNA-associated Sm-like protein LSm2Protein G7b; Small nuclear ribonuclear protein D homolog; snRNP core Sm-like protein Sm-x5Homo sapiens (human)
Exosome complex component CSL4Exosome component 1Homo sapiens (human)
HBS1-like proteinERFSHomo sapiens (human)
U6 snRNA-associated Sm-like protein LSm5Homo sapiens (human)

Compounds (9)

CompoundDescription
Orthophosphate
Uridine TriphosphateUridine 5'-(tetrahydrogen triphosphate). A uracil nucleotide containing three phosphate groups esterified to the sugar moiety.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
7-methylguanosine-5'-monophosphate
7-methylguanosine
Guanosine MonophosphateA guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature.
adenosine monophosphateAdenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position.
Cytidine MonophosphateCytidine (dihydrogen phosphate). A cytosine nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position.
Uridine Monophosphate5'-Uridylic acid. A uracil nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position.