Page last updated: 2024-10-06

DNA Damage Bypass

Proteins (41)

ProteinSynonymsTaxonomy
Ubiquitin-like modifier-activating enzyme 7Ubiquitin-activating enzyme 7; D8; Ubiquitin-activating enzyme E1 homologHomo sapiens (human)
E3 ubiquitin-protein ligase RBX1EC 2.3.2.27; EC 2.3.2.32; E3 ubiquitin-protein transferase RBX1; Protein ZYP; RING finger protein 75; RING-box protein 1; Rbx1; Regulator of cullins 1; ROC1Homo sapiens (human)
DNA damage-binding protein 1DDB p127 subunit; DNA damage-binding protein a; DDBa; Damage-specific DNA-binding protein 1; HBV X-associated protein 1; XAP-1; UV-damaged DNA-binding factor; UV-damaged DNA-binding protein 1; UV-DDB 1; XPE-binding factor; XPE-BF; Xeroderma pigmentosum grHomo sapiens (human)
DNA polymerase epsilon subunit 3Arsenic-transactivated protein; AsTP; Chromatin accessibility complex 17 kDa protein; CHRAC-17; HuCHRAC17; DNA polymerase II subunit 3; DNA polymerase epsilon subunit p17Homo sapiens (human)
DNA polymerase delta subunit 4DNA polymerase delta subunit p12Homo sapiens (human)
Replication protein A 70 kDa DNA-binding subunitRP-A p70; Replication factor A protein 1; RF-A protein 1; Single-stranded DNA-binding proteinHomo sapiens (human)
PCNA-associated factorHepatitis C virus NS5A-transactivated protein 9; HCV NS5A-transactivated protein 9; Overexpressed in anaplastic thyroid carcinoma 1; OEATC-1; PCNA-associated factor of 15 kDa; PAF15; p15PAF; PCNA-clamp-associated factorHomo sapiens (human)
DNA polymerase iotaEC 2.7.7.7; Eta2; RAD30 homolog BHomo sapiens (human)
Ubiquitin-conjugating enzyme E2 BEC 2.3.2.23; E2 ubiquitin-conjugating enzyme B; RAD6 homolog B; HR6B; hHR6B; Ubiquitin carrier protein B; Ubiquitin-conjugating enzyme E2-17 kDa; Ubiquitin-protein ligase BHomo sapiens (human)
Replication factor C subunit 5Activator 1 36 kDa subunit; A1 36 kDa subunit; Activator 1 subunit 5; Replication factor C 36 kDa subunit; RF-C 36 kDa subunit; RFC36Homo sapiens (human)
DNA polymerase etaEC 2.7.7.7; RAD30 homolog A; Xeroderma pigmentosum variant type proteinHomo sapiens (human)
Ubiquitin carboxyl-terminal hydrolase 10EC 3.4.19.12; Deubiquitinating enzyme 10; Ubiquitin thioesterase 10; Ubiquitin-specific-processing protease 10Homo sapiens (human)
Proliferating cell nuclear antigenPCNA; CyclinHomo sapiens (human)
DNA polymerase delta catalytic subunitEC 2.7.7.7; 3'-5' exodeoxyribonuclease; 3.1.11.-; DNA polymerase subunit delta p125Homo sapiens (human)
Transitional endoplasmic reticulum ATPaseTER ATPase; EC 3.6.4.6; 15S Mg(2+)-ATPase p97 subunit; Valosin-containing protein; VCPHomo sapiens (human)
DNA polymerase kappaEC 2.7.7.7; DINB protein; DINPHomo sapiens (human)
Ubiquitin carboxyl-terminal hydrolase 1EC 3.4.19.12; Deubiquitinating enzyme 1; hUBP; Ubiquitin thioesterase 1; Ubiquitin-specific-processing protease 1Homo sapiens (human)
WD repeat-containing protein 48USP1-associated factor 1; WD repeat endosomal protein; p80Homo sapiens (human)
DNA repair protein REV1EC 2.7.7.-; Alpha integrin-binding protein 80; AIBP80; Rev1-like terminal deoxycytidyl transferaseHomo sapiens (human)
Mitotic spindle assembly checkpoint protein MAD2BMitotic arrest deficient 2-like protein 2; MAD2-like protein 2; REV7 homolog; hREV7Homo sapiens (human)
Ubiquitin/ISG15-conjugating enzyme E2 L6EC 2.3.2.23; E2 ubiquitin-conjugating enzyme L6; Retinoic acid-induced gene B protein; RIG-B; UbcH8; Ubiquitin carrier protein L6; Ubiquitin-protein ligase L6Homo sapiens (human)
Ubiquitin carboxyl-terminal hydrolase 43EC 3.4.19.12; Deubiquitinating enzyme 43; Ubiquitin thioesterase 43; Ubiquitin-specific-processing protease 43Homo sapiens (human)
Denticleless protein homologDDB1- and CUL4-associated factor 2; Lethal(2) denticleless protein homolog; Retinoic acid-regulated nuclear matrix-associated proteinHomo sapiens (human)
DNA polymerase zeta catalytic subunitEC 2.7.7.7; Protein reversionless 3-like; REV3-like; hREV3Homo sapiens (human)
Ubiquitin-like protein ISG15Interferon-induced 15 kDa protein; Interferon-induced 17 kDa protein; IP17; Ubiquitin cross-reactive protein; hUCRPHomo sapiens (human)
Replication protein A 32 kDa subunitRP-A p32; Replication factor A protein 2; RF-A protein 2; Replication protein A 34 kDa subunit; RP-A p34Homo sapiens (human)
Replication protein A 14 kDa subunitRP-A p14; Replication factor A protein 3; RF-A protein 3Homo sapiens (human)
Replication factor C subunit 4Activator 1 37 kDa subunit; A1 37 kDa subunit; Activator 1 subunit 4; Replication factor C 37 kDa subunit; RF-C 37 kDa subunit; RFC37Homo sapiens (human)
Replication factor C subunit 2Activator 1 40 kDa subunit; A1 40 kDa subunit; Activator 1 subunit 2; Replication factor C 40 kDa subunit; RF-C 40 kDa subunit; RFC40Homo sapiens (human)
Replication factor C subunit 1Activator 1 140 kDa subunit; A1 140 kDa subunit; Activator 1 large subunit; Activator 1 subunit 1; DNA-binding protein PO-GA; Replication factor C 140 kDa subunit; RF-C 140 kDa subunit; RFC140; Replication factor C large subunitHomo sapiens (human)
Replication factor C subunit 3Activator 1 38 kDa subunit; A1 38 kDa subunit; Activator 1 subunit 3; Replication factor C 38 kDa subunit; RF-C 38 kDa subunit; RFC38Homo sapiens (human)
DNA polymerase delta subunit 2DNA polymerase delta subunit p50Homo sapiens (human)
DNA polymerase epsilon subunit 2DNA polymerase II subunit 2; DNA polymerase epsilon subunit BHomo sapiens (human)
DNA polymerase epsilon catalytic subunit AEC 2.7.7.7; 3'-5' exodeoxyribonuclease; 3.1.11.-; DNA polymerase II subunit AHomo sapiens (human)
E3 ubiquitin/ISG15 ligase TRIM25EC 6.3.2.n3; Estrogen-responsive finger protein; RING finger protein 147; RING-type E3 ubiquitin transferase; 2.3.2.27; RING-type E3 ubiquitin transferase TRIM25; Tripartite motif-containing protein 25; Ubiquitin/ISG15-conjugating enzyme TRIM25; Zinc fingHomo sapiens (human)
DNA polymerase delta subunit 3DNA polymerase delta subunit C; DNA polymerase delta subunit p66; DNA polymerase delta subunit p68Homo sapiens (human)
Nuclear protein localization protein 4 homologProtein NPL4Homo sapiens (human)
Ubiquitin recognition factor in ER-associated degradation protein 1Ubiquitin fusion degradation protein 1; UB fusion protein 1Homo sapiens (human)
RING finger and CHY zinc finger domain-containing protein 1EC 2.3.2.27; Androgen receptor N-terminal-interacting protein; CH-rich-interacting match with PLAG1; E3 ubiquitin-protein ligase Pirh2; RING finger protein 199; RING-type E3 ubiquitin transferase RCHY1; Zinc finger protein 363; p53-induced RING-H2 proteinHomo sapiens (human)
DNA-dependent metalloprotease SPRTNEC 3.4.24.-; DNA damage protein targeting VCP; DVC1; Protein with SprT-like domain at the N terminus; SpartanHomo sapiens (human)
DNA polymerase epsilon subunit 4DNA polymerase II subunit 4; DNA polymerase epsilon subunit p12Homo sapiens (human)

Compounds (6)

CompoundDescription
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
MagnesiumA metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
2'-deoxycytidine 5'-triphosphateRN given refers to unlabeled parent cpd
deoxyadenosine diphosphateRN given refers to parent cpd.