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D-myo-Inositol (1,4,5)-Trisphosphate Biosynthesis

Proteins (4)

ProteinSynonymsTaxonomy
Phosphatidylinositol 4-kinase alpha 1PI4-kinase alpha 1; PtdIns-4-kinase alpha 1; EC 2.7.1.67; Phosphatidylinositol 4-OH kinase alpha1; AtPI4Kalpha1; PI-4Kalpha1Arabidopsis thaliana (thale cress)
Phosphatidylinositol 4-phosphate 5-kinase 1AtPIP5K1; EC 2.7.1.68; 1-phosphatidylinositol 4-phosphate kinase 1; Diphosphoinositide kinase 1; PtdIns(4)P-5-kinase 1Arabidopsis thaliana (thale cress)
Phosphoinositide phospholipase C 1EC 3.1.4.11; Phosphoinositide phospholipase PLC1; AtPLC1; AtPLC1S; PI-PLC1Arabidopsis thaliana (thale cress)
CDP-diacylglycerol--inositol 3-phosphatidyltransferase 1EC 2.7.8.11; Phosphatidylinositol synthase 1; AtPIS1; PI synthase 1; PtdIns synthase 1Arabidopsis thaliana (thale cress)

Compounds (7)

CompoundDescription
InositolAn isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
hydronium ion
Adenosine TriphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
Adenosine DiphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
Cytidine MonophosphateCytidine (dihydrogen phosphate). A cytosine nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position.
Inositol 1,4,5-TrisphosphateIntracellular messenger formed by the action of phospholipase C on phosphatidylinositol 4,5-bisphosphate, which is one of the phospholipids that make up the cell membrane. Inositol 1,4,5-trisphosphate is released into the cytoplasm where it releases calcium ions from internal stores within the cell's endoplasmic reticulum. These calcium ions stimulate the activity of B kinase or calmodulin.