Page last updated: 2024-10-06

D-Glucarate and D-Galactarate Degradation

Proteins (10)

ProteinSynonymsTaxonomy
Pyruvate kinase IEC 2.7.1.40; PK-1Escherichia coli K-12
Pyruvate kinase IIEC 2.7.1.40; PK-2Escherichia coli K-12
Galactarate dehydratase (L-threo-forming)GalcD; EC 4.2.1.42Escherichia coli K-12
5-keto-4-deoxy-D-glucarate aldolaseKDGluc aldolase; KDGlucA; EC 4.1.2.20; 2-dehydro-3-deoxy-D-glucarate aldolase; 2-keto-3-deoxy-D-glucarate aldolase; 5-dehydro-4-deoxy-D-glucarate aldolase; Alpha-keto-beta-deoxy-D-glucarate aldolaseEscherichia coli K-12
EnolaseEC 4.2.1.11; 2-phospho-D-glycerate hydro-lyase; 2-phosphoglycerate dehydrataseEscherichia coli K-12
2-hydroxy-3-oxopropionate reductaseEC 1.1.1.60; Tartronate semialdehyde reductase; TSAREscherichia coli K-12
Glycerate 2-kinaseEC 2.7.1.165; Glycerate kinase 1; GK1Escherichia coli K-12
Glucarate dehydrataseGDH; GlucD; EC 4.2.1.40Escherichia coli K-12
Phosphoenolpyruvate synthasePEP synthase; EC 2.7.9.2; Pyruvate, water dikinaseEscherichia coli K-12
Probable glucarate transporterD-glucarate permeaseEscherichia coli K-12

Compounds (19)

CompoundDescription
hydronium ion
pyruvic acidAn intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
Orthophosphate
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
NADH
Adenosine TriphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
adenosine monophosphateAdenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Coenzyme A
galactaric acidSTRUCTURE; RN given refers to parent cpd
phosphoenolpyruvateA monocarboxylic acid anion derived from selective deprotonation of the carboxy group of phosphoenolpyruvic acid. It is a metabolic intermediate in GLYCOLYSIS; GLUCONEOGENESIS; and other pathways.
tartronate semialdehyde
galactaric acidSTRUCTURE; RN given refers to parent cpd
glyceric acidfound in urine of patient with D-glyceric acidemia & hyperglycinaemia; RN given refers to parent cpd without isomeric designation
NADA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
2-phosphoglycerateRN given refers to cpd without isomeric designation
acetyl coenzyme aAcetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.
creolinfrom refined coal tar oils