| Protein | Synonyms | Taxonomy |
|---|
| Multidrug resistance-associated protein 1 | EC 7.6.2.2; ATP-binding cassette sub-family C member 1; Glutathione-S-conjugate-translocating ATPase ABCC1; 7.6.2.3; Leukotriene C(4) transporter; LTC4 transporter | Homo sapiens (human) |
| Cobalamin trafficking protein CblD | CblD; Methylmalonic aciduria and homocystinuria type D protein, mitochondrial | Homo sapiens (human) |
| Low-density lipoprotein receptor-related protein 2 | LRP-2; Glycoprotein 330; gp330; Megalin | Homo sapiens (human) |
| Methionine synthase | MS; EC 2.1.1.13; 5-methyltetrahydrofolate--homocysteine methyltransferase; Cobalamin-dependent methionine synthase; Vitamin-B12 dependent methionine synthase | Homo sapiens (human) |
| Cyanocobalamin reductase / alkylcobalamin dealkylase | Alkylcobalamin:glutathione S-alkyltransferase; 2.5.1.151; CblC; Cyanocobalamin reductase (cyanide-eliminating); 1.16.1.6; Methylmalonic aciduria and homocystinuria type C protein; MMACHC | Homo sapiens (human) |
| Cubilin | 460 kDa receptor; Intestinal intrinsic factor receptor; Intrinsic factor-cobalamin receptor; Intrinsic factor-vitamin B12 receptor | Homo sapiens (human) |
| Methylmalonyl-CoA mutase, mitochondrial | MCM; EC 5.4.99.2; Methylmalonyl-CoA isomerase | Homo sapiens (human) |
| Methionine synthase reductase | MSR; EC 1.16.1.8; Aquacobalamin reductase; AqCbl reductase; 1.16.1.- | Homo sapiens (human) |
| CD320 antigen | 8D6 antigen; FDC-signaling molecule 8D6; FDC-SM-8D6; Transcobalamin receptor; TCblR | Homo sapiens (human) |
| Cobalamin binding intrinsic factor | Gastric intrinsic factor; Intrinsic factor; IF; INF | Homo sapiens (human) |
| Corrinoid adenosyltransferase | EC 2.5.1.17; Cob(II)alamin adenosyltransferase; Cob(II)yrinic acid a,c-diamide adenosyltransferase; Cobinamide/cobalamin adenosyltransferase; Methylmalonic aciduria type B protein | Homo sapiens (human) |
| Low density lipoprotein receptor adapter protein 1 | Autosomal recessive hypercholesterolemia protein | Homo sapiens (human) |
| Lysosomal cobalamin transporter ABCD4 | ATP-binding cassette sub-family D member 4; PMP70-related protein; P70R; Peroxisomal membrane protein 1-like; PXMP1-L; Peroxisomal membrane protein 69; PMP69 | Homo sapiens (human) |
| Transcobalamin-1 | TC-1; Haptocorrin; HC; Protein R; Transcobalamin I; TC I; TCI | Homo sapiens (human) |
| Transcobalamin-2 | TC-2; Transcobalamin II; TC II; TCII | Homo sapiens (human) |
| Methylmalonic aciduria type A protein, mitochondrial | EC 3.6.-.- | Homo sapiens (human) |
| Protein amnionless | | Homo sapiens (human) |
| Lysosomal cobalamin transport escort protein LMBD1 | LMBD1; HDAg-L-interacting protein NESI; LMBR1 domain-containing protein 1; Nuclear export signal-interacting protein | Homo sapiens (human) |
| Compound | Description |
|---|
| hydronium ion | |
| NADH | |
| Zinc | A metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn. |
| Orthophosphate | |
| Flavin Mononucleotide | A coenzyme for a number of oxidative enzymes including NADH DEHYDROGENASE. It is the principal form in which RIBOFLAVIN is found in cells and tissues. |
| Cobalamins | |
| adenosine diphosphate | Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position. |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| 5-methyltetrahydrofolate | |
| 1,5-dihydro-FAD | chromophore component of E coli DNA photolyase |
| cobamamide | |
| nad | A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed) |
| NADP | Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed) |
| NADP | Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed) |
| adenosine triphosphate | An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. |
| hydrogen cyanide | Hydrogen cyanide (HCN); A toxic liquid or colorless gas. It is found in the smoke of various tobacco products and released by combustion of nitrogen-containing organic materials. |
| s-adenosylmethionine | Physiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed) |
| Flavin-Adenine Dinucleotide | A condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase. (Lehninger, Principles of Biochemistry, 1982, p972) |