Page last updated: 2024-10-06

Cleavage of the damaged pyrimidine

Proteins (9)

ProteinSynonymsTaxonomy
Endonuclease III-like protein 1hNTH1; EC 3.2.2.-; EC 4.2.99.18; Bifunctional DNA N-glycosylase/DNA-(apurinic or apyrimidinic site) lyase; DNA glycosylase/AP lyaseHomo sapiens (human)
Protection of telomeres protein 1hPot1; POT1-like telomere end-binding proteinHomo sapiens (human)
Endonuclease 8-like 1EC 3.2.2.-; EC 4.2.99.18; DNA glycosylase/AP lyase Neil1; DNA-(apurinic or apyrimidinic site) lyase Neil1; Endonuclease VIII-like 1; FPG1; Nei homolog 1; NEH1; Nei-like protein 1Homo sapiens (human)
N-glycosylase/DNA lyaseHomo sapiens (human)
Endonuclease 8-like 3EC 3.2.2.-; EC 4.2.99.18; DNA glycosylase FPG2; DNA glycosylase/AP lyase Neil3; Endonuclease VIII-like 3; Nei-like protein 3Homo sapiens (human)
Endonuclease 8-like 2EC 3.2.2.-; EC 4.2.99.18; DNA glycosylase/AP lyase Neil2; DNA-(apurinic or apyrimidinic site) lyase Neil2; Endonuclease VIII-like 2; Nei homolog 2; NEH2; Nei-like protein 2Homo sapiens (human)
Methyl-CpG-binding domain protein 4EC 3.2.2.-; Methyl-CpG-binding endonuclease 1; Methyl-CpG-binding protein MBD4; Mismatch-specific DNA N-glycosylaseHomo sapiens (human)
G/T mismatch-specific thymine DNA glycosylaseEC 3.2.2.29; Thymine-DNA glycosylase; hTDGHomo sapiens (human)
Single-strand selective monofunctional uracil DNA glycosylaseEC 3.2.2.-Homo sapiens (human)

Compounds (9)

CompoundDescription
3,n(4)-ethanocytosine
thymineOne of four constituent bases of DNA.
4,6-diamino-5-n-formamidopyrimidineformed when adenine is exposed to ionizing radiation
uracilOne of four nucleotide bases in the nucleic acid RNA.
2,6-diamino-4-hydroxy-5-formamidopyrimidinestructure given in first source
cytosine glycolstructure given in first source
thymine glycolforms photodimers (thymine dimers) under UV; RN given refers to cpd without isomeric designation
dihydrouracil
5-hydroxyuracilused in treatment of colonic adenocarcinoma