Page last updated: 2024-10-06

Class I PI3K signaling events mediated by Akt

Proteins (27)

ProteinSynonymsTaxonomy
Target of rapamycin complex 2 subunit MAPKAP1TORC2 subunit MAPKAP1; Mitogen-activated protein kinase 2-associated protein 1; Stress-activated map kinase-interacting protein 1; SAPK-interacting protein 1; mSIN1Homo sapiens (human)
Inhibitor of nuclear factor kappa-B kinase subunit alphaI-kappa-B kinase alpha; IKK-A; IKK-alpha; IkBKA; IkappaB kinase; EC 2.7.11.10; Conserved helix-loop-helix ubiquitous kinase; I-kappa-B kinase 1; IKK1; Nuclear factor NF-kappa-B inhibitor kinase alpha; NFKBIKA; Transcription factor 16; TCF-16Homo sapiens (human)
3-phosphoinositide-dependent protein kinase 1hPDK1; EC 2.7.11.1Homo sapiens (human)
RAF proto-oncogene serine/threonine-protein kinaseEC 2.7.11.1; Proto-oncogene c-RAF; cRaf; Raf-1Homo sapiens (human)
Heat shock protein HSP 90-alphaEC 3.6.4.10; Heat shock 86 kDa; HSP 86; HSP86; Lipopolysaccharide-associated protein 2; LAP-2; LPS-associated protein 2; Renal carcinoma antigen NY-REN-38Homo sapiens (human)
Proto-oncogene tyrosine-protein kinase SrcEC 2.7.10.2; Proto-oncogene c-Src; pp60c-src; p60-SrcHomo sapiens (human)
RAC-alpha serine/threonine-protein kinaseEC 2.7.11.1; Protein kinase B; PKB; Protein kinase B alpha; PKB alpha; Proto-oncogene c-Akt; RAC-PK-alphaHomo sapiens (human)
RAC-beta serine/threonine-protein kinaseEC 2.7.11.1; Protein kinase Akt-2; Protein kinase B beta; PKB beta; RAC-PK-betaHomo sapiens (human)
Glycogen synthase kinase-3 betaGSK-3 beta; EC 2.7.11.26; Serine/threonine-protein kinase GSK3B; 2.7.11.1Homo sapiens (human)
Bcl-2-like protein 1Bcl2-L-1; Apoptosis regulator Bcl-XHomo sapiens (human)
cAMP-dependent protein kinase catalytic subunit alphaPKA C-alpha; EC 2.7.11.11Homo sapiens (human)
Serine/threonine-protein kinase mTOREC 2.7.11.1; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; Mammalian target of rapamycin; mTOR; Mechanistic target of rapamycin; Rapamycin and FKBP12 target 1; Rapamycin target protein 1Homo sapiens (human)
Caspase-9CASP-9; EC 3.4.22.62; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; APAF-3; ICE-like apoptotic protease 6; ICE-LAP6Homo sapiens (human)
DNA-dependent protein kinase catalytic subunitDNA-PK catalytic subunit; DNA-PKcs; EC 2.7.11.1; DNPK1; p460Homo sapiens (human)
Bcl2-associated agonist of cell death BAD; Bcl-2-binding component 6; Bcl-2-like protein 8; Bcl2-L-8; Bcl-xL/Bcl-2-associated death promoter; Bcl2 antagonist of cell deathHomo sapiens (human)
Mitogen-activated protein kinase kinase kinase 5EC 2.7.11.25; Apoptosis signal-regulating kinase 1; ASK-1; MAPK/ERK kinase kinase 5; MEK kinase 5; MEKK 5Homo sapiens (human)
RAC-gamma serine/threonine-protein kinaseEC 2.7.11.1; Protein kinase Akt-3; Protein kinase B gamma; PKB gamma; RAC-PK-gamma; STK-2Homo sapiens (human)
Cyclin-dependent kinase inhibitor 1BCyclin-dependent kinase inhibitor p27; p27Kip1Homo sapiens (human)
14-3-3 protein sigmaEpithelial cell marker protein 1; StratifinHomo sapiens (human)
Solute carrier family 2, facilitated glucose transporter member 4Glucose transporter type 4, insulin-responsive; GLUT-4Homo sapiens (human)
Cyclin-dependent kinase inhibitor 1CDK-interacting protein 1; Melanoma differentiation-associated protein 6; MDA-6; p21Homo sapiens (human)
Forkhead box protein O1Forkhead box protein O1A; Forkhead in rhabdomyosarcomaHomo sapiens (human)
Rapamycin-insensitive companion of mTORAVO3 homolog; hAVO3Homo sapiens (human)
Target of rapamycin complex subunit LST8TORC subunit LST8; G protein beta subunit-like; Gable; Protein GbetaL; Mammalian lethal with SEC13 protein 8; mLST8Homo sapiens (human)
14-3-3 protein zeta/deltaProtein kinase C inhibitor protein 1; KCIP-1Homo sapiens (human)
Importin subunit alpha-5Karyopherin subunit alpha-1; Nucleoprotein interactor 1; NPI-1; RAG cohort protein 2; SRP1-betaHomo sapiens (human)
TBC1 domain family member 4Akt substrate of 160 kDa; AS160Homo sapiens (human)

Compounds (0)

CompoundDescription