| Protein | Synonyms | Taxonomy |
|---|
| 3-dehydroquinate dehydratase | 3-dehydroquinase; EC 4.2.1.10; Type II DHQase | Mycobacterium tuberculosis H37Rv |
| Chorismate synthase | CS; EC 4.2.3.5; 5-enolpyruvylshikimate-3-phosphate phospholyase | Mycobacterium tuberculosis H37Rv |
| Shikimate kinase | SK; EC 2.7.1.71 | Mycobacterium tuberculosis H37Rv |
| 3-phosphoshikimate 1-carboxyvinyltransferase | EC 2.5.1.19; 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS | Mycobacterium tuberculosis H37Rv |
| Phospho-2-dehydro-3-deoxyheptonate aldolase AroG | EC 2.5.1.54; 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase | Mycobacterium tuberculosis H37Rv |
| 3-dehydroquinate synthase | DHQS; EC 4.2.3.4 | Mycobacterium tuberculosis H37Rv |
| Shikimate 5-dehydrogenase | | Mycobacterium tuberculosis CDC1551 |
| Compound | Description |
|---|
| hydronium ion | |
| Orthophosphate | |
| Manganese | A trace element with atomic symbol Mn, atomic number 25, and atomic weight 54.94. It is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver. (From AMA Drug Evaluations Annual 1992, p2035) |
| NADH | |
| Adenosine Triphosphate | An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. |
| adenosine diphosphate | Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position. |
| flavin mononucleotide | A coenzyme for a number of oxidative enzymes including NADH DEHYDROGENASE. It is the principal form in which RIBOFLAVIN is found in cells and tissues. |
| Magnesium | A metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION. |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| chorismic acid | A cyclohexadiene carboxylic acid derived from SHIKIMIC ACID and a precursor for the biosynthesis of UBIQUINONE and the AROMATIC AMINO ACIDS. |
| shikimate-3-phosphate | |
| Excitatory Postsynaptic Potentials | Depolarization of membrane potentials at the SYNAPTIC MEMBRANES of target neurons during neurotransmission. Excitatory postsynaptic potentials can singly or in summation reach the trigger threshold for ACTION POTENTIALS. |
| Tolbutamide | A sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290) |
| 3-dehydroshikimate | |
| NAD | A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed) |
| shikimic acid | A tri-hydroxy cyclohexene carboxylic acid important in biosynthesis of so many compounds that the shikimate pathway is named after it. |
| creolin | from refined coal tar oils |
| Phosphoenolpyruvate | A monocarboxylic acid anion derived from selective deprotonation of the carboxy group of phosphoenolpyruvic acid. It is a metabolic intermediate in GLYCOLYSIS; GLUCONEOGENESIS; and other pathways. |