Page last updated: 2024-10-06

Cholesterol metabolism with Bloch and Kandutsch-Russell pathways

Proteins (0)

Compounds (33)

CompoundDescription
CholesterolThe principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils.
zymostenolRN given refers to (3beta,5alpha)-isomer; RN for cpd without isomeric designation not available 9/88
isopentenyl pyrophosphatesubstrate for isopentenyl pyrophosphate isomerase; RN given refers to unlabeled cpd; a nonpeptide mycobacterial antigen that stimulates gamma delta T cells
24-hydroxycholesterol
24,25-epoxycholesterolRn given refers to (3alpha,5beta)-isomer; structure given in first source
4-hydroxycholesterol
5-diphosphomevalonic acidRN given refers to ion(1-)
7-dehydrocholesterolRN given refers to (3beta)-isomer; structure; main provitamin in skin that is converted by sunlight to cholecalciferol (vitamin D3)
desmosterolAn intermediate in the synthesis of cholesterol.
24-dehydroprovitamin D3
24,25-dihydrolanosterol
4,4-dimethylcholesta-8,14,24-trienola meiosis activating sterol; RN given refers to (5alpha,3beta)-isomer
3-hydroxy-3-methylglutaryl-coenzyme aRN given refers to cpd without isomeric designation
farnesyl pyrophosphatea sesquiterpene that dimerizes to SQUALENE; RN given refers to cpd without isomeric designation
geranyl pyrophosphateRN given refers to (E)-isomer
2,3-oxidosqualenean oxidized derivative of SQUALENE that can fold in several ways: chair-boat-chair-boat to LANOSTEROL; chair-chair-chair-boat to dammarane; or all chair to hopane and on to cycloartenol; RN given refers to (all-Z)-isomer
cholesta-7,24-dien-3-olminor metabolite of in vitro incubation of mevalonic acid with yeast; structure; RN given refers to (3beta,5alpha)-isomer; RN for cpd without isomeric designation not avail 10/89
4-methylcholest-8-en-3-ol, (3beta,4alpha,5alpha)-isomer
lathosterolRN given refers to (3beta,5alpha)-isomer
cholest-5-en-3 beta,7 alpha-diolsubstrate for hydroxysteroid dehydrogenase; RN given refers to (3beta,7alpha)-isomer
4,4-dimethyl-5-alpha-cholesta-(8,24)-dien-3-beta-olRN given refers to (3beta,5alpha)-isomer
32-hydroxylanosterolfound in mevalonate-treated cell cultures
lanosterolA triterpene that derives from the chair-boat-chair-boat folding of 2,3-oxidosqualene. It is metabolized to CHOLESTEROL and CUCURBITACINS.
mevalonic acidA dihydroxy monocarboxylic acid and precursor in the biosynthetic pathway known as the mevalonate pathway, which produces terpenes and steroids that are vital for diverse cellular functions.
phosphomevalonate
acetyl coenzyme aAcetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.
palmitoleic acidfactor capable of converting CaATPase into MgATPase; RN given refers to cpd without isomeric designation
3,3-dimethylallyl pyrophosphateisomeric with isopentenyl pyrophosphate
25-hydroxycholesterol
7-ketocholesterolinhibits uptake of cholesterol in rabbit aorta
cholest-4-en-3-one
zymosterola 4,14-desmethyl intermediate between LANOSTEROL and CHOLESTEROL
cholest-5-ene-3 beta,26-diolisolated from human brain