Protein | Synonyms | Taxonomy |
Oxysterols receptor LXR-beta | Liver X receptor beta; Nuclear receptor NER; Nuclear receptor subfamily 1 group H member 2; Ubiquitously-expressed nuclear receptor | Homo sapiens (human) |
Lanosterol 14-alpha demethylase | LDM; EC 1.14.14.154; CYPLI; Cytochrome P450 51A1; Cytochrome P450-14DM; Cytochrome P45014DM; Cytochrome P450LI; Sterol 14-alpha demethylase | Homo sapiens (human) |
Cytochrome P450 7A1 | 24-hydroxycholesterol 7-alpha-hydroxylase; 1.14.14.26; CYPVII; Cholesterol 7-alpha-hydroxylase; Cholesterol 7-alpha-monooxygenase; 1.14.14.23 | Homo sapiens (human) |
Sterol regulatory element-binding protein 1 | SREBP-1; Class D basic helix-loop-helix protein 1; bHLHd1; Sterol regulatory element-binding transcription factor 1 | Homo sapiens (human) |
Hydroxymethylglutaryl-CoA synthase, cytoplasmic | HMG-CoA synthase; EC 2.3.3.10; 3-hydroxy-3-methylglutaryl coenzyme A synthase | Homo sapiens (human) |
Compound | Description |
Cholesterol | The principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils. |
squalene | A natural 30-carbon triterpene. |
Magnesium | A metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION. |
presqualene monophosphate | structure in first source |
zymostenol | RN given refers to (3beta,5alpha)-isomer; RN for cpd without isomeric designation not available 9/88 |
isopentenyl pyrophosphate | substrate for isopentenyl pyrophosphate isomerase; RN given refers to unlabeled cpd; a nonpeptide mycobacterial antigen that stimulates gamma delta T cells |
24-hydroxycholesterol | |
4,4-dimethylcholesta-8,14-dien-3-ol | RN refers to (3beta,5alpha)-isomer; a meiosis-activating sterol |
24,25-epoxycholesterol | Rn given refers to (3alpha,5beta)-isomer; structure given in first source |
4-hydroxycholesterol | |
7-dehydrocholesterol | RN given refers to (3beta)-isomer; structure; main provitamin in skin that is converted by sunlight to cholecalciferol (vitamin D3) |
desmosterol | An intermediate in the synthesis of cholesterol. |
24-dehydroprovitamin D3 | |
24,25-dihydrolanosterol | |
4,4-dimethylcholesta-8,14,24-trienol | a meiosis activating sterol; RN given refers to (5alpha,3beta)-isomer |
geranyl pyrophosphate | RN given refers to (E)-isomer |
Mevalonic Acid | A dihydroxy monocarboxylic acid and precursor in the biosynthetic pathway known as the mevalonate pathway, which produces terpenes and steroids that are vital for diverse cellular functions. |
presqualene pyrophosphate | |
2,3-oxidosqualene | an oxidized derivative of SQUALENE that can fold in several ways: chair-boat-chair-boat to LANOSTEROL; chair-chair-chair-boat to dammarane; or all chair to hopane and on to cycloartenol; RN given refers to (all-Z)-isomer |
lathosterol | RN given refers to (3beta,5alpha)-isomer |
cholest-5-en-3 beta,7 alpha-diol | substrate for hydroxysteroid dehydrogenase; RN given refers to (3beta,7alpha)-isomer |
4,4-dimethyl-5-alpha-cholesta-(8,24)-dien-3-beta-ol | RN given refers to (3beta,5alpha)-isomer |
lanosterol | A triterpene that derives from the chair-boat-chair-boat folding of 2,3-oxidosqualene. It is metabolized to CHOLESTEROL and CUCURBITACINS. |
acetyl coenzyme a | Acetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent. |
25-hydroxycholesterol | |
7-ketocholesterol | inhibits uptake of cholesterol in rabbit aorta |
cholest-4-en-3-one | |
acetoacetyl coa | |
zymosterol | a 4,14-desmethyl intermediate between LANOSTEROL and CHOLESTEROL |
cholest-5-ene-3 beta,26-diol | isolated from human brain |