Page last updated: 2024-10-06

Caspase Cascade in Apoptosis

Proteins (55)

ProteinSynonymsTaxonomy
VimentinHomo sapiens (human)
Amyloid-beta precursor proteinAPP; ABPP; APPI; Alzheimer disease amyloid protein; Amyloid precursor protein; Amyloid-beta A4 protein; Cerebral vascular amyloid peptide; CVAP; PreA4; Protease nexin-II; PN-IIHomo sapiens (human)
DNA topoisomerase 1EC 5.6.2.1; DNA topoisomerase IHomo sapiens (human)
RAC-alpha serine/threonine-protein kinaseEC 2.7.11.1; Protein kinase B; PKB; Protein kinase B alpha; PKB alpha; Proto-oncogene c-Akt; RAC-PK-alphaHomo sapiens (human)
E3 ubiquitin-protein ligase XIAPEC 2.3.2.27; Baculoviral IAP repeat-containing protein 4; IAP-like protein; ILP; hILP; Inhibitor of apoptosis protein 3; IAP-3; hIAP-3; hIAP3; RING-type E3 ubiquitin transferase XIAP; X-linked inhibitor of apoptosis protein; X-linked IAPHomo sapiens (human)
Focal adhesion kinase 1FADK 1; EC 2.7.10.2; Focal adhesion kinase-related nonkinase; FRNK; Protein phosphatase 1 regulatory subunit 71; PPP1R71; Protein-tyrosine kinase 2; p125FAK; pp125FAKHomo sapiens (human)
Bcl-2-like protein 1Bcl2-L-1; Apoptosis regulator Bcl-XHomo sapiens (human)
Mitogen-activated protein kinase kinase kinase 1EC 2.7.11.25; MAPK/ERK kinase kinase 1; MEK kinase 1; MEKK 1Homo sapiens (human)
Baculoviral IAP repeat-containing protein 3EC 2.3.2.27; Apoptosis inhibitor 2; API2; Cellular inhibitor of apoptosis 2; C-IAP2; IAP homolog C; Inhibitor of apoptosis protein 1; hIAP-1; hIAP1; RING finger protein 49; RING-type E3 ubiquitin transferase BIRC3; TNFR2-TRAF-signaling complex protein 1Homo sapiens (human)
Caspase-8CASP-8; EC 3.4.22.61; Apoptotic cysteine protease; Apoptotic protease Mch-5; CAP4; FADD-homologous ICE/ced-3-like protease; FADD-like ICE; FLICE; ICE-like apoptotic protease 5; MORT1-associated ced-3 homolog; MACHHomo sapiens (human)
Tumor necrosis factor ligand superfamily member 6Apoptosis antigen ligand; APTL; CD95 ligand; CD95-L; Fas antigen ligand; Fas ligand; FasLHomo sapiens (human)
Tumor necrosis factor ligand superfamily member 10Apo-2 ligand; Apo-2L; TNF-related apoptosis-inducing ligand; Protein TRAILHomo sapiens (human)
Tumor necrosis factor receptor superfamily member 10ADeath receptor 4; TNF-related apoptosis-inducing ligand receptor 1; TRAIL receptor 1; TRAIL-R1Homo sapiens (human)
Poly [ADP-ribose] polymerase 1PARP-1; EC 2.4.2.30; ADP-ribosyltransferase diphtheria toxin-like 1; ARTD1; DNA ADP-ribosyltransferase PARP1; 2.4.2.-; NAD(+) ADP-ribosyltransferase 1; ADPRT 1; Poly[ADP-ribose] synthase 1; Protein poly-ADP-ribosyltransferase PARP1; 2.4.2.-Homo sapiens (human)
Granzyme BEC 3.4.21.79; C11; CTLA-1; Cathepsin G-like 1; CTSGL1; Cytotoxic T-lymphocyte proteinase 2; Lymphocyte protease; Fragmentin-2; Granzyme-2; Human lymphocyte protein; HLP; SECT; T-cell serine protease 1-3EHomo sapiens (human)
Apoptosis regulator Bcl-2Homo sapiens (human)
Caspase-3CASP-3; EC 3.4.22.56; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; SCA-1Homo sapiens (human)
Caspase-2CASP-2; EC 3.4.22.55; Neural precursor cell expressed developmentally down-regulated protein 2; NEDD-2; Protease ICH-1Homo sapiens (human)
LIM domain kinase 1LIMK-1; EC 2.7.11.1Homo sapiens (human)
Caspase-9CASP-9; EC 3.4.22.62; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; APAF-3; ICE-like apoptotic protease 6; ICE-LAP6Homo sapiens (human)
Caspase-6CASP-6; EC 3.4.22.59; Apoptotic protease Mch-2Homo sapiens (human)
BH3-interacting domain death agonistp22 BID; BIDHomo sapiens (human)
Apoptosis regulator BAX Bcl-2-like protein 4; Bcl2-L-4Homo sapiens (human)
Receptor-interacting serine/threonine-protein kinase 1EC 2.7.11.1; Cell death protein RIP; Receptor-interacting protein 1; RIP-1Homo sapiens (human)
GelsolinAGEL; Actin-depolymerizing factor; ADF; BrevinHomo sapiens (human)
Tumor necrosis factor receptor superfamily member 10BDeath receptor 5; TNF-related apoptosis-inducing ligand receptor 2; TRAIL receptor 2; TRAIL-R2Homo sapiens (human)
Tumor necrosis factor receptor superfamily member 1ATumor necrosis factor receptor 1; TNF-R1; Tumor necrosis factor receptor type I; TNF-RI; TNFR-I; p55; p60Homo sapiens (human)
Cytochrome cHomo sapiens (human)
Tumor necrosis factor receptor superfamily member 6Apo-1 antigen; Apoptosis-mediating surface antigen FAS; FASLG receptorHomo sapiens (human)
Sterol regulatory element-binding protein 1SREBP-1; Class D basic helix-loop-helix protein 1; bHLHd1; Sterol regulatory element-binding transcription factor 1Homo sapiens (human)
Apoptotic protease-activating factor 1APAF-1Homo sapiens (human)
Tumor necrosis factorCachectin; TNF-alpha; Tumor necrosis factor ligand superfamily member 2; TNF-aHomo sapiens (human)
Perforin-1P1; Cytolysin; Lymphocyte pore-forming protein; PFPHomo sapiens (human)
Caspase-7CASP-7; EC 3.4.22.60; Apoptotic protease Mch-3; CMH-1; ICE-like apoptotic protease 3; ICE-LAP3Homo sapiens (human)
Caspase-10CASP-10; EC 3.4.22.63; Apoptotic protease Mch-4; FAS-associated death domain protein interleukin-1B-converting enzyme 2; FLICE2; ICE-like apoptotic protease 4Homo sapiens (human)
Keratin, type I cytoskeletal 18Cell proliferation-inducing gene 46 protein; Cytokeratin-18; CK-18; Keratin-18; K18Homo sapiens (human)
TNF receptor-associated factor 2EC 2.3.2.27; E3 ubiquitin-protein ligase TRAF2; RING-type E3 ubiquitin transferase TRAF2; Tumor necrosis factor type 2 receptor-associated protein 3Homo sapiens (human)
FAS-associated death domain proteinFAS-associating death domain-containing protein; Growth-inhibiting gene 3 protein; Mediator of receptor induced toxicity; Protein FADDHomo sapiens (human)
DNA fragmentation factor subunit alphaDNA fragmentation factor 45 kDa subunit; DFF-45; Inhibitor of CAD; ICADHomo sapiens (human)
Serine proteinase inhibitor 2Serp-2; Serpin-2; Cytokine response modifier protein A; Hemorrhage-inducing 38 kDa protein; ICE inhibitorCowpox virus (Brighton Red)
DNA fragmentation factor subunit betaEC 3.-.-.-; Caspase-activated deoxyribonuclease; CAD; Caspase-activated DNase; Caspase-activated nuclease; CPAN; DNA fragmentation factor 40 kDa subunit; DFF-40Homo sapiens (human)
p53-induced death domain-containing protein 1EC 3.4.21.-; Leucine-rich repeat and death domain-containing proteinHomo sapiens (human)
DNA-binding protein SATB1Special AT-rich sequence-binding protein 1Homo sapiens (human)
Growth arrest-specific protein 2GAS-2Homo sapiens (human)
Transcription factor AP-2-alphaAP2-alpha; AP-2 transcription factor; Activating enhancer-binding protein 2-alpha; Activator protein 2; AP-2Homo sapiens (human)
Rho GDP-dissociation inhibitor 2Rho GDI 2; Ly-GDI; Rho-GDI betaHomo sapiens (human)
Actin, alpha skeletal muscleAlpha-actin-1Homo sapiens (human)
Death domain-containing protein CRADDCaspase and RIP adapter with death domain; RIP-associated protein with a death domainHomo sapiens (human)
Spectrin alpha chain, non-erythrocytic 1Alpha-II spectrin; Fodrin alpha chain; Spectrin, non-erythroid alpha subunitHomo sapiens (human)
Nuclear mitotic apparatus protein 1Nuclear matrix protein-22; NMP-22; Nuclear mitotic apparatus protein; NuMA protein; SP-H antigenHomo sapiens (human)
Tumor necrosis factor receptor type 1-associated DEATH domain proteinTNFR1-associated DEATH domain protein; TNFRSF1A-associated via death domainHomo sapiens (human)
MAP kinase-activating death domain proteinDifferentially expressed in normal and neoplastic cells; Insulinoma glucagonoma clone 20; Rab3 GDP/GTP exchange factorHomo sapiens (human)
Diablo homolog, mitochondrialDirect IAP-binding protein with low pI; Second mitochondria-derived activator of caspase; SmacHomo sapiens (human)
Cofilin-2Cofilin, muscle isoformHomo sapiens (human)
HSLK (Ste20-related serine\\/threonine kinase)Homo sapiens (human)

Compounds (0)

CompoundDescription