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Biosynthesis of Siderophore Group Nonribosomal Peptides

Proteins (18)

ProteinSynonymsTaxonomy
Enterobactin synthase component EEC 6.3.2.14; 2,3-dihydroxybenzoate-AMP ligase; DHB-AMP ligase; 2,3-dihydroxybenzoate-AMP synthase; 2.7.7.58; Dihydroxybenzoic acid-activating enzyme; Enterochelin synthase E; S-dihydroxybenzoyltransferase; 2.5.1.-Escherichia coli K-12
Enterobactin synthase component BEC 6.3.2.14; Enterobactin biosynthesis bifunctional protein EntB; Enterochelin synthase BEscherichia coli K-12
Outer membrane protein TolCMultidrug efflux pump subunit TolC; Outer membrane factor TolCEscherichia coli K-12
Isochorismate synthase EntCEC 5.4.4.2; Isochorismate mutaseEscherichia coli K-12
Enterochelin esteraseFerric enterobactin esteraseEscherichia coli K-12
Serine/threonine transporter SstTNa(+)/serine-threonine symporterEscherichia coli O157:H7
Protein TonBEscherichia coli K-12
Ferrienterobactin receptorEnterobactin outer-membrane receptorEscherichia coli K-12
Biopolymer transport protein ExbBEscherichia coli K-12
Biopolymer transport protein ExbDEscherichia coli K-12
Ferrienterobactin-binding periplasmic proteinEscherichia coli K-12
Enterobactin synthase component FEC 2.7.7.-; Enterochelin synthase F; Serine-activating enzyme; Seryl-AMP ligaseEscherichia coli K-12
2,3-dihydro-2,3-dihydroxybenzoate dehydrogenaseDiDHB-DH; EC 1.3.1.28; Trans-2,3-dihydro-2,3-dihydroxybenzoate dehydrogenaseEscherichia coli K-12
Enterobactin synthase component D4'-phosphopantetheinyl transferase EntD; 2.7.8.-; Enterochelin synthase DEscherichia coli K-12
Ferric enterobactin transport system permease protein FepDEscherichia coli K-12
Ferric enterobactin transport system permease protein FepGEscherichia coli K-12
Ferric enterobactin transport ATP-binding protein FepCEscherichia coli K-12
Enterobactin exporter EntSProtein p43Escherichia coli K-12

Compounds (17)

CompoundDescription
hydronium ion
pyruvic acidAn intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
ironA metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN.
IronA metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN.
NADH
Adenosine TriphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
adenosine monophosphateAdenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position.
SodiumA member of the alkali group of metals. It has the atomic symbol Na, atomic number 11, and atomic weight 23.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
chorismic acidA cyclohexadiene carboxylic acid derived from SHIKIMIC ACID and a precursor for the biosynthesis of UBIQUINONE and the AROMATIC AMINO ACIDS.
2,3-dihydroxybenzoic acidRN given refers to parent cpd
enterobactinAn iron-binding cyclic trimer of 2,3-dihydroxy-N-benzoyl-L-serine. It is produced by E COLI and other enteric bacteria.
isochorismate
NADA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
serineA non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
pyrophosphate