Page last updated: 2024-10-06
Betaine Metabolism
Proteins (8)
| Protein | Synonyms | Taxonomy |
|---|
| Adenosylhomocysteinase | AdoHcyase; EC 3.3.1.1; S-adenosyl-L-homocysteine hydrolase | Homo sapiens (human) |
| S-adenosylmethionine synthase isoform type-2 | AdoMet synthase 2; EC 2.5.1.6; Methionine adenosyltransferase 2; MAT 2; Methionine adenosyltransferase II; MAT-II | Homo sapiens (human) |
| Betaine--homocysteine S-methyltransferase 1 | EC 2.1.1.5 | Homo sapiens (human) |
| Methionine synthase | MS; EC 2.1.1.13; 5-methyltetrahydrofolate--homocysteine methyltransferase; Cobalamin-dependent methionine synthase; Vitamin-B12 dependent methionine synthase | Homo sapiens (human) |
| Choline dehydrogenase, mitochondrial | CDH; CHD; EC 1.1.99.1 | Homo sapiens (human) |
| Phosphatidylethanolamine N-methyltransferase | PEAMT; PEMT; EC 2.1.1.17; EC 2.1.1.71; PEMT2; Phospholipid methyltransferase; PLMT | Homo sapiens (human) |
| Alpha-aminoadipic semialdehyde dehydrogenase | Alpha-AASA dehydrogenase; EC 1.2.1.31; Aldehyde dehydrogenase family 7 member A1; 1.2.1.3; Antiquitin-1; Betaine aldehyde dehydrogenase; 1.2.1.8; Delta1-piperideine-6-carboxylate dehydrogenase; P6c dehydrogenase | Homo sapiens (human) |
| Methionine adenosyltransferase 2 subunit beta | Methionine adenosyltransferase II beta; MAT II beta; Putative dTDP-4-keto-6-deoxy-D-glucose 4-reductase | Homo sapiens (human) |
Compounds (14)
| Compound | Description |
|---|
| Orthophosphate | |
| betaine | A naturally occurring compound that has been of interest for its role in osmoregulation. As a drug, betaine hydrochloride has been used as a source of hydrochloric acid in the treatment of hypochlorhydria. Betaine has also been used in the treatment of liver disorders, for hyperkalemia, for homocystinuria, and for gastrointestinal disturbances. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1341) |
| choline | A basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism. |
| NADH | |
| Adenosine Triphosphate | An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. |
| adenosine | A nucleoside that is composed of ADENINE and D-RIBOSE. Adenosine or adenosine derivatives play many important biological roles in addition to being components of DNA and RNA. Adenosine itself is a neurotransmitter. |
| methionine | A sulfur-containing essential L-amino acid that is important in many body functions. |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| betaine aldehyde | |
| ubiquinone q1 | interacts with iron atom to form acceptor quinone complex |
| NAD | A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed) |
| dimethylglycine | metabolic product of calcium pangamate; mutagen when mixed with nitrite; RN given refers to parent cpd |
| s-adenosylmethionine | Physiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed) |
| pyrophosphate | |