| Protein | Synonyms | Taxonomy |
|---|
| Equilibrative nucleoside transporter 2 | 36 kDa nucleolar protein HNP36; Delayed-early response protein 12; Equilibrative nitrobenzylmercaptopurine riboside-insensitive nucleoside transporter; Equilibrative NBMPR-insensitive nucleoside transporter; Hydrophobic nucleolar protein, 36 kDa; Nucleosi | Homo sapiens (human) |
| Adenylosuccinate synthetase isozyme 2 | AMPSase 2; AdSS 2; EC 6.3.4.4; Adenylosuccinate synthetase, acidic isozyme; Adenylosuccinate synthetase, liver isozyme; L-type adenylosuccinate synthetase; IMP--aspartate ligase 2 | Homo sapiens (human) |
| Multidrug resistance-associated protein 5 | ATP-binding cassette sub-family C member 5; Multi-specific organic anion transporter C; MOAT-C; SMRP; pABC11 | Homo sapiens (human) |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4D | EC 3.1.4.53; DPDE3; PDE43 | Homo sapiens (human) |
| Multifunctional protein ADE2 | | Homo sapiens (human) |
| GMP synthase [glutamine-hydrolyzing] | EC 6.3.5.2; GMP synthetase; Glutamine amidotransferase | Homo sapiens (human) |
| Multidrug resistance-associated protein 4 | ATP-binding cassette sub-family C member 4; MRP/cMOAT-related ABC transporter; Multi-specific organic anion transporter B; MOAT-B | Homo sapiens (human) |
| Hypoxanthine-guanine phosphoribosyltransferase | HGPRT; HGPRTase; EC 2.4.2.8 | Homo sapiens (human) |
| Xanthine dehydrogenase/oxidase | | Homo sapiens (human) |
| Equilibrative nucleoside transporter 1 | Equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter; Equilibrative NBMPR-sensitive nucleoside transporter; Nucleoside transporter, es-type; Solute carrier family 29 member 1 | Homo sapiens (human) |
| cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | EC 3.1.4.17; EC 3.1.4.35 | Homo sapiens (human) |
| Phosphoribosylformylglycinamidine synthase | FGAM synthase; FGAMS; EC 6.3.5.3; Formylglycinamide ribonucleotide amidotransferase; FGAR amidotransferase; FGAR-AT; Formylglycinamide ribotide amidotransferase | Homo sapiens (human) |
| Cytosolic purine 5'-nucleotidase | EC 3.1.3.5; Cytosolic 5'-nucleotidase II | Homo sapiens (human) |
| Amidophosphoribosyltransferase | ATase; EC 2.4.2.14; Glutamine phosphoribosylpyrophosphate amidotransferase; GPAT | Homo sapiens (human) |
| Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] | EC 3.6.1.17; Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase; Ap4A hydrolase; Ap4Aase; Diadenosine tetraphosphatase; Nucleoside diphosphate-linked moiety X motif 2; Nudix motif 2 | Homo sapiens (human) |
| Guanylate kinase | EC 2.7.4.8; GMP kinase; Guanylate kinase 1 | Homo sapiens (human) |
| Sodium/nucleoside cotransporter 2 | Concentrative nucleoside transporter 2; CNT 2; hCNT2; Na(+)/nucleoside cotransporter 2; Sodium-coupled nucleoside transporter 2; Sodium/purine nucleoside co-transporter; SPNT; Solute carrier family 28 member 2 | Homo sapiens (human) |
| Inosine-5'-monophosphate dehydrogenase 1 | IMP dehydrogenase 1; IMPD 1; IMPDH 1; EC 1.1.1.205; IMPDH-I | Homo sapiens (human) |
| Ribonucleoside-diphosphate reductase large subunit | EC 1.17.4.1; Ribonucleoside-diphosphate reductase subunit M1; Ribonucleotide reductase large subunit | Homo sapiens (human) |
| Ribonucleoside-diphosphate reductase subunit M2 | EC 1.17.4.1; Ribonucleotide reductase small chain; Ribonucleotide reductase small subunit | Homo sapiens (human) |
| Bifunctional purine biosynthesis protein ATIC | AICAR transformylase/inosine monophosphate cyclohydrolase; ATIC | Homo sapiens (human) |
| Adenosine kinase | AK; EC 2.7.1.20; Adenosine 5'-phosphotransferase | Homo sapiens (human) |
| Ras-related C3 botulinum toxin substrate 1 | EC 3.6.5.2; Cell migration-inducing gene 5 protein; Ras-like protein TC25; p21-Rac1 | Homo sapiens (human) |
| Adenylate cyclase type 2 | EC 4.6.1.1; ATP pyrophosphate-lyase 2; Adenylate cyclase type II; Adenylyl cyclase 2 | Homo sapiens (human) |
| Deoxyguanosine kinase, mitochondrial | EC 2.7.1.113; Deoxyadenosine kinase, mitochondrial; 2.7.1.76 | Homo sapiens (human) |
| Ectonucleoside triphosphate diphosphohydrolase 8 | E-NTPDase 8; NTPDase 8; NTPDase8; EC 3.6.1.5 | Homo sapiens (human) |
| Guanine deaminase | Guanase; Guanine aminase; EC 3.5.4.3; Guanine aminohydrolase; GAH; p51-nedasin | Homo sapiens (human) |
| Ectonucleoside triphosphate diphosphohydrolase 5 | NTPDase 5; EC 3.6.1.6; CD39 antigen-like 4; ER-UDPase; Guanosine-diphosphatase ENTPD5; GDPase ENTPD5; 3.6.1.42; Nucleoside diphosphatase; Uridine-diphosphatase ENTPD5; UDPase ENTPD5 | Homo sapiens (human) |
| Purine nucleoside phosphorylase | PNP; EC 2.4.2.1; Inosine phosphorylase; Inosine-guanosine phosphorylase | Homo sapiens (human) |
| Adenosine deaminase | EC 3.5.4.4; Adenosine aminohydrolase | Homo sapiens (human) |
| Thioredoxin | Trx; ATL-derived factor; ADF; Surface-associated sulphydryl protein; SASP | Homo sapiens (human) |
| Trifunctional purine biosynthetic protein adenosine-3 | | Homo sapiens (human) |
| AMP deaminase 1 | EC 3.5.4.6; AMP deaminase isoform M; Myoadenylate deaminase | Homo sapiens (human) |
| Guanylate cyclase soluble subunit alpha-2 | GCS-alpha-2; EC 4.6.1.2 | Homo sapiens (human) |
| Aldehyde oxidase | EC 1.2.3.1; Aldehyde oxidase 1; Azaheterocycle hydroxylase; 1.17.3.- | Homo sapiens (human) |
| Adenylate kinase isoenzyme 1 | AK 1; EC 2.7.4.3; EC 2.7.4.6; ATP-AMP transphosphorylase 1; ATP:AMP phosphotransferase; Adenylate monophosphate kinase; Myokinase | Homo sapiens (human) |
| Thiopurine S-methyltransferase | EC 2.1.1.67; Thiopurine methyltransferase | Homo sapiens (human) |
| Adenylosuccinate lyase | ADSL; ASL; EC 4.3.2.2; Adenylosuccinase; ASase | Homo sapiens (human) |
| Guanylate cyclase soluble subunit beta-1 | GCS-beta-1; EC 4.6.1.2; Guanylate cyclase soluble subunit beta-3; GCS-beta-3; Soluble guanylate cyclase small subunit | Homo sapiens (human) |
| Inosine triphosphate pyrophosphatase | ITPase; Inosine triphosphatase; EC 3.6.1.9; Non-canonical purine NTP pyrophosphatase; Non-standard purine NTP pyrophosphatase; Nucleoside-triphosphate diphosphatase; Nucleoside-triphosphate pyrophosphatase; NTPase; Putative oncogene protein hlc14-06-p | Homo sapiens (human) |
| ADP-sugar pyrophosphatase | EC 3.6.1.13; 8-oxo-dGDP phosphatase; 3.6.1.58; Nuclear ATP-synthesis protein NUDIX5; 2.7.7.96; Nucleoside diphosphate-linked moiety X motif 5; Nudix motif 5; hNUDT5; YSA1H | Homo sapiens (human) |
| Solute carrier family 28 member 3 | Concentrative Na(+)-nucleoside cotransporter 3; CNT 3; hCNT3 | Homo sapiens (human) |
| Adenine phosphoribosyltransferase | APRT; EC 2.4.2.7 | Homo sapiens (human) |
| GMP reductase 1 | GMPR 1; EC 1.7.1.7; Guanosine 5'-monophosphate oxidoreductase 1; Guanosine monophosphate reductase 1 | Homo sapiens (human) |
| Nucleoside diphosphate kinase 6 | NDK 6; NDP kinase 6; EC 2.7.4.6; Inhibitor of p53-induced apoptosis-alpha; IPIA-alpha; nm23-H6 | Homo sapiens (human) |
| Ribose-phosphate pyrophosphokinase 3 | EC 2.7.6.1; Phosphoribosyl pyrophosphate synthase 1-like 1; PRPS1-like 1; Phosphoribosyl pyrophosphate synthase III; PRS-III | Homo sapiens (human) |
| Outer mitochondrial transmembrane helix translocase | EC 7.4.2.-; ATPase family AAA domain-containing protein 1; hATAD1; Thorase | Homo sapiens (human) |
| Compound | Description |
|---|
| phosphoric acid | concise etchant is 37% H3PO4 |
| Orthophosphate | |
| adenine | A purine base and a fundamental unit of ADENINE NUCLEOTIDES. |
| ammonium hydroxide | The hydroxy salt of ammonium ion. It is formed when AMMONIA reacts with water molecules in solution. |
| azathioprine | An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed) |
| Carbon Dioxide | A colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals. |
| glutamic acid | A non-essential amino acid naturally occurring in the L-form. Glutamic acid is the most common excitatory neurotransmitter in the CENTRAL NERVOUS SYSTEM. |
| NADH | |
| Adenosine Triphosphate | An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. |
| glutamine | A non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes. It is synthesized from GLUTAMIC ACID and AMMONIA. It is the principal carrier of NITROGEN in the body and is an important energy source for many cells. |
| adenosine diphosphate | Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position. |
| adenosine monophosphate | Adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position. |
| adenosine | A nucleoside that is composed of ADENINE and D-RIBOSE. Adenosine or adenosine derivatives play many important biological roles in addition to being components of DNA and RNA. Adenosine itself is a neurotransmitter. |
| mercaptopurine | An antimetabolite antineoplastic agent with immunosuppressant properties. It interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, usually in combination with other drugs, in the treatment of or in remission maintenance programs for leukemia. |
| phosphoribosyl pyrophosphate | The key substance in the biosynthesis of histidine, tryptophan, and purine and pyrimidine nucleotides. |
| Hydrogen Peroxide | A strong oxidizing agent used in aqueous solution as a ripening agent, bleach, and topical anti-infective. It is relatively unstable and solutions deteriorate over time unless stabilized by the addition of acetanilide or similar organic materials. |
| Sodium | A member of the alkali group of metals. It has the atomic symbol Na, atomic number 11, and atomic weight 23. |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| Oxygen | An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration. |
| thioinosine | Sulfhydryl analog of INOSINE that inhibits nucleoside transport across erythrocyte plasma membranes, and has immunosuppressive properties. It has been used similarly to MERCAPTOPURINE in the treatment of leukemia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p503) |
| 6-thioguanosine 5'-triphosphate | |
| Adenosine Diphosphate Ribose | An ester formed between the aldehydic carbon of RIBOSE and the terminal phosphate of ADENOSINE DIPHOSPHATE. It is produced by the hydrolysis of nicotinamide-adenine dinucleotide (NAD) by a variety of enzymes, some of which transfer an ADP-ribosyl group to target proteins. |
| 6-thioguanylic acid | |
| phosphoribosyl-N-formylglycineamide | |
| glycineamide ribonucleotide | structure |
| uric acid | An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN. |
| 2'-deoxy-5'-adenosine monophosphate | RN given refers to parent cpd |
| 2'-deoxyadenosine | was (MH) DEOXYADENOSINE (68-89) |
| 2'-deoxyadenosine triphosphate | RN given refers to unlabeled parent cpd |
| 6-thiouric acid | structure |
| thioinosinic acid | |
| 6-thioguanylic acid | |
| ribose 1-phosphate | RN given refers to (D)-isomer |
| 2-deoxyribose 1-phosphate | |
| 6-methylthiopurine | |
| NAD | A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed) |
| xanthosine | |
| xanthosine 5'-triphosphate | RN given refers to parent cpd |
| 8-hydroxythioguanine | structure in first source |
| xanthine | A purine base found in most body tissues and fluids, certain plants, and some urinary calculi. It is an intermediate in the degradation of adenosine monophosphate to uric acid, being formed by oxidation of hypoxanthine. The methylated xanthine compounds caffeine, theobromine, and theophylline and their derivatives are used in medicine for their bronchodilator effects. (Dorland, 28th ed) |
| saicar | adenosylsuccinase catalyzes its conversion to AICAR |
| aminoimidazole ribotide | |
| carboxyaminoimidazole ribotide | reacts with alanosine to form antimetabolite; substrate for EC 4.1.1.21; structure in second source |
| 5-formamidoimidazole-4-carboxamide ribotide | purine precursor |
| s-adenosylmethionine | Physiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed) |
| creolin | from refined coal tar oils |
| Cyclic AMP | An adenine nucleotide containing one phosphate group which is esterified to both the 3'- and 5'-positions of the sugar moiety. It is a second messenger and a key intracellular regulator, functioning as a mediator of activity for a number of hormones, including epinephrine, glucagon, and ACTH. |
| pyrophosphate | |
| aica ribonucleotide | purine precursor that has antineoplastic activity |
| aminoimidazole carboxamide | An imidazole derivative which is a metabolite of the antineoplastic agents BIC and DIC. By itself, or as the ribonucleotide, it is used as a condensation agent in the preparation of nucleosides and nucleotides. Compounded with orotic acid, it is used to treat liver diseases. |