Page last updated: 2024-10-06
Arginine Metabolism
Proteins (28)
| Protein | Synonyms | Taxonomy |
|---|---|---|
| Acetylornithine/succinyldiaminopimelate aminotransferase | ACOAT; DapATase; Succinyldiaminopimelate transferase; EC 2.6.1.11; EC 2.6.1.17 | Escherichia coli K-12 |
| Carbamoyl-phosphate synthase small chain | EC 6.3.5.5; Carbamoyl-phosphate synthetase glutamine chain | Escherichia coli K-12 |
| 4-aminobutyrate aminotransferase GabT | EC 2.6.1.19; 5-aminovalerate transaminase; 2.6.1.48; GABA aminotransferase; GABA-AT; Gamma-amino-N-butyrate transaminase; GABA transaminase; Glutamate:succinic semialdehyde transaminase; L-AIBAT | Escherichia coli K-12 |
| Succinate-semialdehyde dehydrogenase [NADP(+)] GabD | SSDH; EC 1.2.1.79; Glutarate-semialdehyde dehydrogenase; 1.2.1.- | Escherichia coli K-12 |
| Putrescine aminotransferase | PAT; PATase; EC 2.6.1.82; Cadaverine transaminase; Diamine transaminase; 2.6.1.29; Putrescine transaminase; Putrescine--2-oxoglutaric acid transaminase; Putrescine:2-OG aminotransferase | Escherichia coli K-12 |
| 4-aminobutyrate aminotransferase PuuE | EC 2.6.1.19; GABA aminotransferase; GABA-AT; Gamma-amino-N-butyrate transaminase; GABA transaminase; Glutamate:succinic semialdehyde transaminase | Escherichia coli K-12 |
| Gamma-aminobutyraldehyde dehydrogenase | ABALDH; EC 1.2.1.19; 1-pyrroline dehydrogenase; 4-aminobutanal dehydrogenase; 5-aminopentanal dehydrogenase; 1.2.1.- | Escherichia coli K-12 |
| Succinate semialdehyde dehydrogenase [NAD(P)+] Sad | SSADH; SSDH; EC 1.2.1.16 | Escherichia coli K-12 |
| Argininosuccinate synthase | EC 6.3.4.5; Citrulline--aspartate ligase | Escherichia coli K-12 |
| Agmatinase | EC 3.5.3.11; Agmatine ureohydrolase; AUH | Escherichia coli K-12 |
| Biodegradative arginine decarboxylase | ADC; EC 4.1.1.19 | Escherichia coli K-12 |
| Acetylglutamate kinase | EC 2.7.2.8; N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; NAGK | Escherichia coli K-12 |
| Acetylornithine deacetylase | AO; Acetylornithinase; EC 3.5.1.16; N-acetylornithinase; NAO | Escherichia coli K-12 |
| N-succinylglutamate 5-semialdehyde dehydrogenase | EC 1.2.1.71; Succinylglutamic semialdehyde dehydrogenase; SGSD | Escherichia coli K-12 |
| Arginine N-succinyltransferase | AST; EC 2.3.1.109; AOST | Escherichia coli K-12 |
| Gamma-glutamyl-gamma-aminobutyrate hydrolase PuuD | Gamma-Glu-GABA hydrolase; EC 3.5.1.94 | Escherichia coli K-12 |
| NADP/NAD-dependent aldehyde dehydrogenase PuuC | ALDH; EC 1.2.1.5; 3-hydroxypropionaldehyde dehydrogenase; Gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase; Gamma-Glu-gamma-aminobutyraldehyde dehydrogenase | Escherichia coli K-12 |
| Carbamoyl-phosphate synthase large chain | EC 6.3.5.5; Carbamoyl-phosphate synthetase ammonia chain | Escherichia coli K-12 |
| Ornithine carbamoyltransferase subunit I | OTCase-1; EC 2.1.3.3 | Escherichia coli K-12 |
| Ornithine carbamoyltransferase subunit F | OTCase-2; EC 2.1.3.3 | Escherichia coli K-12 |
| N-acetyl-gamma-glutamyl-phosphate reductase | AGPR; EC 1.2.1.38; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase | Escherichia coli K-12 |
| Argininosuccinate lyase | ASAL; EC 4.3.2.1; Arginosuccinase | Escherichia coli K-12 |
| Gamma-glutamylputrescine oxidoreductase | Gamma-Glu-Put oxidase; Gamma-glutamylputrescine oxidase; EC 1.4.3.- | Escherichia coli K-12 |
| Succinylglutamate desuccinylase | EC 3.5.1.96 | Escherichia coli K-12 |
| N-succinylarginine dihydrolase | EC 3.5.3.23 | Escherichia coli K-12 |
| Succinylornithine transaminase | SOAT; EC 2.6.1.81; Carbon starvation protein C; Succinylornithine aminotransferase | Escherichia coli K-12 |
| Gamma-glutamylputrescine synthetase PuuA | Gamma-Glu-Put synthetase; EC 6.3.1.11; Glutamate--putrescine ligase | Escherichia coli K-12 |
| Peroxisome proliferator-activated receptor gamma | Homo sapiens (human) |
Compounds (35)
| Compound | Description |
|---|---|
| hydronium ion | |
| Orthophosphate | |
| succinic acid | A water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is also used in foods as a sequestrant, buffer, and a neutralizing agent. (Hawley's Condensed Chemical Dictionary, 12th ed, p1099; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1851) |
| urea | A compound formed in the liver from ammonia produced by the deamination of amino acids. It is the principal end product of protein catabolism and constitutes about one half of the total urinary solids. |
| gamma-aminobutyric acid | The most common inhibitory neurotransmitter in the central nervous system. |
| acetic acid | Product of the oxidation of ethanol and of the destructive distillation of wood. It is used locally, occasionally internally, as a counterirritant and also as a reagent. (Stedman, 26th ed) |
| Carbon Dioxide | A colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals. |
| glutamic acid | A non-essential amino acid naturally occurring in the L-form. Glutamic acid is the most common excitatory neurotransmitter in the CENTRAL NERVOUS SYSTEM. |
| NADH | |
| Adenosine Triphosphate | An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. |
| glutamine | A non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes. It is synthesized from GLUTAMIC ACID and AMMONIA. It is the principal carrier of NITROGEN in the body and is an important energy source for many cells. |
| adenosine diphosphate | Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position. |
| adenosine monophosphate | Adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position. |
| ornithine | An amino acid produced in the urea cycle by the splitting off of urea from arginine. |
| hydrogen carbonate | |
| Hydrogen Peroxide | A strong oxidizing agent used in aqueous solution as a ripening agent, bleach, and topical anti-infective. It is relatively unstable and solutions deteriorate over time unless stabilized by the addition of acetanilide or similar organic materials. |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| Oxygen | An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration. |
| Coenzyme A | |
| succinic semialdehyde | structure |
| 4-aminobutyraldehyde | |
| Argininosuccinic Acid | This amino acid is formed during the urea cycle from citrulline, aspartate and ATP. This reaction is catalyzed by argininosuccinic acid synthetase. |
| N-acetylglutamate, (DL)-isomer | |
| N-acetyl-L-glutamic acid gamma-semialdehyde | |
| agmatine | Decarboxylated arginine, isolated from several plant and animal sources, e.g., pollen, ergot, herring sperm, octopus muscle. |
| carbamyl phosphate | The monoanhydride of carbamic acid with PHOSPHORIC ACID. It is an important intermediate metabolite and is synthesized enzymatically by CARBAMYL-PHOSPHATE SYNTHASE (AMMONIA) and CARBAMOYL-PHOSPHATE SYNTHASE (GLUTAMINE-HYDROLYZING). |
| alpha-ketoglutaric acid | |
| NAD | A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed) |
| putrescine | A toxic diamine formed by putrefaction from the decarboxylation of arginine and ornithine. |
| N(2)-succinylornithine | |
| gamma glutamyl GABA | structure given in first source |
| N(delta)-acetylornithine | RN given refers to (L)-isomer |
| acetyl coenzyme a | Acetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent. |
| creolin | from refined coal tar oils |
| pyrophosphate |