Page last updated: 2024-10-06

Apoptosis signaling pathway

Proteins (54)

ProteinSynonymsTaxonomy
Dual specificity mitogen-activated protein kinase kinase 3 MAP kinase kinase 3; MAPKK 3; EC 2.7.12.2; MAPK/ERK kinase 3; MEK 3Mus musculus (house mouse)
Receptor-interacting serine/threonine-protein kinase 1 EC 2.7.11.1; Cell death protein RIP; Receptor-interacting protein 1; RIP-1Mus musculus (house mouse)
Protein kinase C alpha typePKC-A; PKC-alpha; EC 2.7.11.13Homo sapiens (human)
Dual specificity mitogen-activated protein kinase kinase 4MAP kinase kinase 4; MAPKK 4; EC 2.7.12.2; C-JUN N-terminal kinase kinase 1; JNK kinase 1; JNKK 1; JNK-activating kinase 1; MAPK/ERK kinase 4; MEK 4; SAPK/ERK kinase 1; SEK1Mus musculus (house mouse)
Tumor necrosis factor ligand superfamily member 10Apo-2 ligand; Apo-2L; TNF-related apoptosis-inducing ligand; Protein TRAILHomo sapiens (human)
Transcription factor AP-1Proto-oncogene c-JunGallus gallus (chicken)
Bcl-2-like protein 1 Bcl2-L-1; Apoptosis regulator Bcl-XRattus norvegicus (Norway rat)
Caspase-9CASP-9; EC 3.4.22.62; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; APAF-3; ICE-like apoptotic protease 6; ICE-LAP6Homo sapiens (human)
Mitogen-activated protein kinase kinase kinase 14EC 2.7.11.25; NF-kappa-beta-inducing kinase; HsNIK; Serine/threonine-protein kinase NIKHomo sapiens (human)
RAC-gamma serine/threonine-protein kinaseEC 2.7.11.1; Protein kinase Akt-3; Protein kinase B gamma; PKB gamma; RAC-PK-gamma; STK-2Homo sapiens (human)
Proto-oncogene c-FosCellular oncogene fosMus musculus (house mouse)
Cation-independent mannose-6-phosphate receptorCI Man-6-P receptor; CI-MPR; M6PR; 300 kDa mannose 6-phosphate receptor; MPR 300; Insulin-like growth factor 2 receptor; Insulin-like growth factor II receptor; IGF-II receptor; M6P/IGF2 receptor; M6P/IGF2RMus musculus (house mouse)
Caspase-3 CASP-3; EC 3.4.22.56; Apopain; Cysteine protease CPP32; CPP-32; IRP; LICE; Protein Yama; SREBP cleavage activity 1; SCA-1Rattus norvegicus (Norway rat)
Bcl-2 homologous antagonist/killerApoptosis regulator BAK; Bcl-2-like protein 7; Bcl2-L-7Homo sapiens (human)
Inhibitor of nuclear factor kappa-B kinase subunit betaI-kappa-B-kinase beta; IKK-B; IKK-beta; IkBKB; EC 2.7.11.10; I-kappa-B kinase 2; IKK2; Nuclear factor NF-kappa-B inhibitor kinase beta; NFKBIKB; Serine/threonine protein kinase IKBKB; 2.7.11.1Rattus norvegicus (Norway rat)
Bcl-2-like protein 11Bcl2-L-11; Bcl2-interacting mediator of cell deathHomo sapiens (human)
Caspase 8Macaca mulatta (Rhesus monkey)
Death domain-associated protein 6 DaxxMus musculus (house mouse)
Mitogen-activated protein kinase 10AtMPK10; MAP kinase 10; EC 2.7.11.24Arabidopsis thaliana (thale cress)
Apoptosis regulator Bcl-2Bos taurus (cattle)
Granzyme B(G,H)EC 3.4.21.79; CTLA-1; Cytotoxic cell protease 1; CCP1; Fragmentin-2Mus musculus (house mouse)
Dual specificity mitogen-activated protein kinase kinase 7MAP kinase kinase 7; MAPKK 7; EC 2.7.12.2; JNK-activating kinase 2; MAPK/ERK kinase 7; MEK 7; c-Jun N-terminal kinase kinase 2; JNK kinase 2; JNKK 2Rattus norvegicus (Norway rat)
Tumor necrosis factor receptor superfamily member 1ATumor necrosis factor receptor 1; TNF-R1; Tumor necrosis factor receptor type I; TNF-RI; TNFR-I; p55; p60Mus musculus (house mouse)
Endonuclease G, mitochondrialEndo G; EC 3.1.30.-Mus musculus (house mouse)
Bcl-2-interacting killerApoptosis inducer NBK; Bik-like killer proteinMus musculus (house mouse)
Interferon-inducible double-stranded RNA-dependent protein kinase activator APKR-associated protein X; PKR-associating protein X; Protein activator of the interferon-induced protein kinase; Protein kinase, interferon-inducible double-stranded RNA-dependent activatorHomo sapiens (human)
Apoptotic protease-activating factor 1 APAF-1Mus musculus (house mouse)
Cytochrome c, testis-specificMus musculus (house mouse)
Cellular tumor antigen p53 Tumor suppressor p53Rattus norvegicus (Norway rat)
Death domain-containing protein CRADDCaspase and RIP adapter with death domain; RIP-associated protein with a death domainHomo sapiens (human)
Tumor necrosis factor receptor type 1-associated DEATH domain proteinTNFR1-associated DEATH domain protein; TNFRSF1A-associated via death domainHomo sapiens (human)
FAS-associated death domain protein FAS-associating death domain-containing protein; Mediator of receptor induced toxicity; Protein FADDMus musculus (house mouse)
Mitogen-activated protein kinase kinase kinase kinase 5EC 2.7.11.1; MAPK/ERK kinase kinase kinase 5; MEK kinase kinase 5; MEKKK 5Mus musculus (house mouse)
MAP kinase-activating death domain proteinDifferentially expressed in normal and neoplastic cells; Insulinoma glucagonoma clone 20; Rab3 GDP/GTP exchange factorHomo sapiens (human)
Kelch-like protein diabloDrosophila melanogaster (fruit fly)
Apoptosis-inducing factor 1, mitochondrialEC 1.6.99.-; Programmed cell death protein 8Mus musculus (house mouse)
Caspase 10Pan troglodytes (chimpanzee)
Caspase 7, isoform CRA_c Rattus norvegicus (Norway rat)
Inhibitor of apoptosis protein 3Gallus gallus (chicken)
Eukaryotic translation initiation factor 2 subunit 1 Danio rerio (zebrafish)
Phosphatidylinositol-4,5-bisphosphate 3-kinase Canis lupus familiaris (dog)
Protein kinase domain-containing proteinCaenorhabditis elegans
TNF receptor superfamily member 1BMacaca mulatta (Rhesus monkey)
Mitogen-activated protein kinase kinase kinase Macaca mulatta (Rhesus monkey)
TNF receptor superfamily member 10bPan troglodytes (chimpanzee)
Apo-1 antigen Pan troglodytes (chimpanzee)
RELB proto-oncogene, NF-kB subunitPan troglodytes (chimpanzee)
Mitogen-activated protein kinase kinase kinase 1Macaca mulatta (Rhesus monkey)
Eukaryotic translation initiation factor 2-alpha kinase 2Pan troglodytes (chimpanzee)
Baculoviral IAP repeat containing 2Pan troglodytes (chimpanzee)
BZIP domain-containing proteinPan troglodytes (chimpanzee)
NF-kappa-B inhibitor alpha Macaca mulatta (Rhesus monkey)
TNF receptor-associated factor Canis lupus familiaris (dog)
Tumor necrosis factor ligand superfamily member 6CD95 ligand; CD95-L; Fas antigen ligand; Fas ligand; FasLMacaca mulatta (Rhesus monkey)

Compounds (0)

CompoundDescription