Page last updated: 2024-10-06

Amyloid fiber formation

Proteins (17)

ProteinSynonymsTaxonomy
Synphilin-1 Sph1; Alpha-synuclein-interacting proteinHomo sapiens (human)
E3 ubiquitin-protein ligase parkinParkin; EC 2.3.2.31; Parkin RBR E3 ubiquitin-protein ligase; Parkinson juvenile disease protein 2; Parkinson disease protein 2Homo sapiens (human)
Serum amyloid P-componentSAP; 9.5S alpha-1-glycoproteinHomo sapiens (human)
Amyloid-beta precursor proteinAPP; ABPP; APPI; Alzheimer disease amyloid protein; Amyloid precursor protein; Amyloid-beta A4 protein; Cerebral vascular amyloid peptide; CVAP; PreA4; Protease nexin-II; PN-IIHomo sapiens (human)
Beta-secretase 1EC 3.4.23.46; Aspartyl protease 2; ASP2; Asp 2; Beta-site amyloid precursor protein cleaving enzyme 1; Beta-site APP cleaving enzyme 1; Memapsin-2; Membrane-associated aspartic protease 2Homo sapiens (human)
NicastrinHomo sapiens (human)
FurinEC 3.4.21.75; Dibasic-processing enzyme; Paired basic amino acid residue-cleaving enzyme; PACEHomo sapiens (human)
Alpha-synucleinNon-A beta component of AD amyloid; Non-A4 component of amyloid precursor; NACPHomo sapiens (human)
Gamma-secretase subunit PEN-2Presenilin enhancer protein 2Homo sapiens (human)
Probable ubiquitin carboxyl-terminal hydrolase FAF-XEC 3.4.19.12; Deubiquitinating enzyme FAF-X; Fat facets in mammals; hFAM; Fat facets protein-related, X-linked; Ubiquitin thioesterase FAF-X; Ubiquitin-specific protease 9, X chromosome; Ubiquitin-specific-processing protease FAF-XHomo sapiens (human)
Disintegrin and metalloproteinase domain-containing protein 10ADAM 10; EC 3.4.24.81; CDw156; Kuzbanian protein homolog; Mammalian disintegrin-metalloproteaseHomo sapiens (human)
Basement membrane-specific heparan sulfate proteoglycan core proteinHSPG; Perlecan; PLCHomo sapiens (human)
Ubiquitin/ISG15-conjugating enzyme E2 L6EC 2.3.2.23; E2 ubiquitin-conjugating enzyme L6; Retinoic acid-induced gene B protein; RIG-B; UbcH8; Ubiquitin carrier protein L6; Ubiquitin-protein ligase L6Homo sapiens (human)
Apolipoprotein EApo-EHomo sapiens (human)
CalbindinCalbindin D28; D-28K; Vitamin D-dependent calcium-binding protein, avian-typeHomo sapiens (human)
E3 ubiquitin-protein ligase SIAH1EC 2.3.2.27; RING-type E3 ubiquitin transferase SIAH1; Seven in absentia homolog 1; Siah-1; Siah-1aHomo sapiens (human)
Sortilin-related receptorLow-density lipoprotein receptor relative with 11 ligand-binding repeats; LDLR relative with 11 ligand-binding repeats; LR11; SorLA-1; Sorting protein-related receptor containing LDLR class A repeats; SorLAHomo sapiens (human)

Compounds (6)

CompoundDescription
acetic acidProduct of the oxidation of ethanol and of the destructive distillation of wood. It is used locally, occasionally internally, as a counterirritant and also as a reagent. (Stedman, 26th ed)
CalciumA basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
ZincA metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Coenzyme A
Acetyl Coenzyme AAcetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.