Page last updated: 2024-10-06

Amino acids regulate mTORC1

Proteins (22)

ProteinSynonymsTaxonomy
Cytosolic arginine sensor for mTORC1 subunit 1Cellular arginine sensor for mTORC1 protein 1; GATS-like protein 3Homo sapiens (human)
Serine/threonine-protein kinase mTOREC 2.7.11.1; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; Mammalian target of rapamycin; mTOR; Mechanistic target of rapamycin; Rapamycin and FKBP12 target 1; Rapamycin target protein 1Homo sapiens (human)
Regulatory-associated protein of mTORRaptor; p150 target of rapamycin (TOR)-scaffold proteinHomo sapiens (human)
Target of rapamycin complex subunit LST8TORC subunit LST8; G protein beta subunit-like; Gable; Protein GbetaL; Mammalian lethal with SEC13 protein 8; mLST8Homo sapiens (human)
GTP-binding protein RhebRas homolog enriched in brainHomo sapiens (human)
Nucleoporin SEH1GATOR complex protein SEH1; Nup107-160 subcomplex subunit SEH1; SEC13-like proteinHomo sapiens (human)
Cytosolic arginine sensor for mTORC1 subunit 2Cellular arginine sensor for mTORC1 protein 2; GATS-like protein 2Homo sapiens (human)
GATOR complex protein DEPDC5DEP domain-containing protein 5Homo sapiens (human)
Protein SEC13 homologGATOR complex protein SEC13; SEC13-like protein 1; SEC13-related proteinHomo sapiens (human)
GATOR complex protein NPRL3-14 gene protein; Alpha-globin regulatory element-containing gene protein; Nitrogen permease regulator 3-like protein; Protein CGTHBAHomo sapiens (human)
S-adenosylmethionine sensor upstream of mTORC1Probable methyltransferase BMT2 homolog; 2.1.1.-Homo sapiens (human)
KICSTOR complex protein SZT2Seizure threshold 2 protein homologHomo sapiens (human)
GATOR complex protein WDR59WD repeat-containing protein 59Homo sapiens (human)
Sodium-coupled neutral amino acid transporter 9Solute carrier family 38 member 9; Up-regulated in lung cancer 11Homo sapiens (human)
FolliculinBHD skin lesion fibrofolliculoma protein; Birt-Hogg-Dube syndrome proteinHomo sapiens (human)
GATOR complex protein NPRL2Gene 21 protein; G21 protein; Nitrogen permease regulator 2-like protein; NPR2-like protein; Tumor suppressor candidate 4Homo sapiens (human)
KICSTOR complex protein ITFG2Integrin-alpha FG-GAP repeat-containing protein 2Homo sapiens (human)
KICSTOR complex protein C12orf66Homo sapiens (human)
GATOR complex protein WDR24WD repeat-containing protein 24Homo sapiens (human)
GATOR complex protein MIOSMissing oocyte meiosis regulator homologHomo sapiens (human)
SH3 domain-binding protein 4EH-binding protein 10; Transferrin receptor-trafficking proteinHomo sapiens (human)
KICSTOR complex protein kaptinActin-associated protein 2E4Homo sapiens (human)

Compounds (5)

CompoundDescription
ArginineAn essential amino acid that is physiologically active in the L-form.
Orthophosphate
Guanosine MonophosphateA guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature.
Guanosine DiphosphateA guanine nucleotide containing two phosphate groups esterified to the sugar moiety.
s-adenosylmethioninePhysiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed)