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Alpha Linolenic Acid and Linoleic Acid Metabolism

Proteins (5)

ProteinSynonymsTaxonomy
Elongation of very long chain fatty acids protein 4EC 2.3.1.199; 3-keto acyl-CoA synthase ELOVL4; ELOVL fatty acid elongase 4; ELOVL FA elongase 4; Very long chain 3-ketoacyl-CoA synthase 4; Very long chain 3-oxoacyl-CoA synthase 4Homo sapiens (human)
Acyl-CoA (8-3)-desaturaseEC 1.14.19.44; Delta(5) fatty acid desaturase; D5D; Delta(5) desaturase; Delta-5 desaturase; Fatty acid desaturase 1Homo sapiens (human)
Acyl-CoA 6-desaturaseEC 1.14.19.3; Delta(6) fatty acid desaturase; D6D; Delta(6) desaturase; Delta-6 desaturase; Fatty acid desaturase 2Homo sapiens (human)
Cytosolic phospholipase A2 betacPLA2-beta; EC 3.1.1.4; Lysophospholipase A1 group IVB; 3.1.1.5; Phospholipase A2 group IVBHomo sapiens (human)
Elongation of very long chain fatty acids protein 5EC 2.3.1.199; 3-keto acyl-CoA synthase ELOVL5; ELOVL fatty acid elongase 5; ELOVL FA elongase 5; Fatty acid elongase 1; hELO1; Very long chain 3-ketoacyl-CoA synthase 5; Very long chain 3-oxoacyl-CoA synthase 5Homo sapiens (human)

Compounds (13)

CompoundDescription
docosahexaenoate
eicosapentaenoic acidImportant polyunsaturated fatty acid found in fish oils. It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. A diet rich in eicosapentaenoic acid lowers serum lipid concentration, reduces incidence of cardiovascular disorders, prevents platelet aggregation, and inhibits arachidonic acid conversion into the thromboxane-2 and prostaglandin-2 families.
linoleic acidA doubly unsaturated fatty acid, occurring widely in plant glycosides. It is an essential fatty acid in mammalian nutrition and is used in the biosynthesis of prostaglandins and cell membranes. (From Stedman, 26th ed)
gamma-linolenic acidAn omega-6 fatty acid produced in the body as the delta 6-desaturase metabolite of linoleic acid. It is converted to dihomo-gamma-linolenic acid, a biosynthetic precursor of monoenoic prostaglandins such as PGE1. (From Merck Index, 11th ed)
alpha-linolenic acidA fatty acid that is found in plants and involved in the formation of prostaglandins.
8,11,14,17-eicosatetraenoic acid, Z-isomer
arachidonic acidAn unsaturated, essential fatty acid. It is found in animal and human fat as well as in the liver, brain, and glandular organs, and is a constituent of animal phosphatides. It is formed by the synthesis from dietary linoleic acid and is a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes.
8,11,14-eicosatrienoic acidA 20-carbon-chain fatty acid, unsaturated at positions 8, 11, and 14. It differs from arachidonic acid, 5,8,11,14-eicosatetraenoic acid, only at position 5.
stearidonic acidRN given refers to cpd with unknown MF; 18:4 n-3 fatty acid
adrenic acidRN given refers to cpd without isomeric designation
docosapentaenoic acid
tetracosapentaenoic acidRN given refers to (all-Z)-isomer
PhosphatidylcholinesDerivatives of PHOSPHATIDIC ACIDS in which the phosphoric acid is bound in ester linkage to a CHOLINE moiety.