Page last updated: 2024-10-06

Activation of NMDA receptors and postsynaptic events

Proteins (38)

ProteinSynonymsTaxonomy
3-phosphoinositide-dependent protein kinase 1hPDK1; EC 2.7.11.1Homo sapiens (human)
Glutamate receptor ionotropic, NMDA 3BGluN3B; N-methyl-D-aspartate receptor subtype 3B; NMDAR3B; NR3BHomo sapiens (human)
Proto-oncogene tyrosine-protein kinase SrcEC 2.7.10.2; Proto-oncogene c-Src; pp60c-src; p60-SrcHomo sapiens (human)
Mitogen-activated protein kinase 3 MAP kinase 3; MAPK 3; EC 2.7.11.24; ERT2; Extracellular signal-regulated kinase 1; ERK-1; Insulin-stimulated MAP2 kinase; MAP kinase isoform p44; p44-MAPK; Microtubule-associated protein 2 kinase; p44-ERK1Homo sapiens (human)
Mitogen-activated protein kinase 1MAP kinase 1; MAPK 1; EC 2.7.11.24; ERT1; Extracellular signal-regulated kinase 2; ERK-2; MAP kinase isoform p42; p42-MAPK; Mitogen-activated protein kinase 2; MAP kinase 2; MAPK 2Homo sapiens (human)
Glutamate receptor ionotropic, NMDA 2BGluN2B; Glutamate [NMDA] receptor subunit epsilon-2; N-methyl D-aspartate receptor subtype 2B; NMDAR2B; NR2B; N-methyl-D-aspartate receptor subunit 3; NR3; hNR3Homo sapiens (human)
Calcium/calmodulin-dependent protein kinase type II subunit gammaCaM kinase II subunit gamma; CaMK-II subunit gamma; EC 2.7.11.17Homo sapiens (human)
Glutamate receptor ionotropic, NMDA 2CGluN2C; Glutamate [NMDA] receptor subunit epsilon-3; N-methyl D-aspartate receptor subtype 2C; NMDAR2C; NR2CHomo sapiens (human)
Glutamate receptor ionotropic, NMDA 2DGluN2D; EB11; Glutamate [NMDA] receptor subunit epsilon-4; N-methyl D-aspartate receptor subtype 2D; NMDAR2D; NR2DHomo sapiens (human)
Glutamate receptor 1GluR-1; AMPA-selective glutamate receptor 1; GluR-A; GluR-K1; Glutamate receptor ionotropic, AMPA 1; GluA1Homo sapiens (human)
Glutamate receptor 2GluR-2; AMPA-selective glutamate receptor 2; GluR-B; GluR-K2; Glutamate receptor ionotropic, AMPA 2; GluA2Homo sapiens (human)
Glutamate receptor ionotropic, NMDA 1GluN1; Glutamate [NMDA] receptor subunit zeta-1; N-methyl-D-aspartate receptor subunit NR1; NMD-R1Homo sapiens (human)
Glutamate receptor ionotropic, NMDA 2AGluN2A; Glutamate [NMDA] receptor subunit epsilon-1; N-methyl D-aspartate receptor subtype 2A; NMDAR2A; NR2A; hNR2AHomo sapiens (human)
Calcium/calmodulin-dependent protein kinase type 1EC 2.7.11.17; CaM kinase I; CaM-KI; CaM kinase I alpha; CaMKI-alphaHomo sapiens (human)
Calcium/calmodulin-dependent protein kinase type IVCaMK IV; EC 2.7.11.17; CaM kinase-GRHomo sapiens (human)
Cyclic AMP-responsive element-binding protein 1CREB-1; cAMP-responsive element-binding protein 1Homo sapiens (human)
Ras-related C3 botulinum toxin substrate 1EC 3.6.5.2; Cell migration-inducing gene 5 protein; Ras-like protein TC25; p21-Rac1Homo sapiens (human)
Disks large homolog 4Postsynaptic density protein 95; PSD-95; Synapse-associated protein 90; SAP-90; SAP90Homo sapiens (human)
Ras-specific guanine nucleotide-releasing factor 1Ras-GRF1; Guanine nucleotide-releasing protein; GNRP; Ras-specific nucleotide exchange factor CDC25Homo sapiens (human)
Peripheral plasma membrane protein CASKhCASK; EC 2.7.11.1; Calcium/calmodulin-dependent serine protein kinase; Protein lin-2 homologHomo sapiens (human)
Calmodulin-1Homo sapiens (human)
Calcium/calmodulin-dependent protein kinase type II subunit betaCaM kinase II subunit beta; CaMK-II subunit beta; EC 2.7.11.17Homo sapiens (human)
Glutamate receptor ionotropic, NMDA 3AGluN3A; N-methyl-D-aspartate receptor subtype 3A; NMDAR3A; NR3A; NMDAR-LHomo sapiens (human)
Calcium/calmodulin-dependent protein kinase kinase 2CaM-KK 2; CaM-kinase kinase 2; CaMKK 2; EC 2.7.11.17; Calcium/calmodulin-dependent protein kinase kinase beta; CaM-KK beta; CaM-kinase kinase beta; CaMKK betaHomo sapiens (human)
ARF GTPase-activating protein GIT1ARF GAP GIT1; Cool-associated and tyrosine-phosphorylated protein 1; CAT-1; CAT1; G protein-coupled receptor kinase-interactor 1; GRK-interacting protein 1Homo sapiens (human)
Importin subunit alpha-1Karyopherin subunit alpha-2; RAG cohort protein 1; SRP1-alphaHomo sapiens (human)
NeurograninNg; RC3Homo sapiens (human)
Leucine-rich repeat-containing protein 7Densin-180; Densin; Protein LAP1Homo sapiens (human)
Alpha-actinin-2Alpha-actinin skeletal muscle isoform 2; F-actin cross-linking proteinHomo sapiens (human)
Ras-specific guanine nucleotide-releasing factor 2Ras-GRF2; Ras guanine nucleotide exchange factor 2Homo sapiens (human)
Neurofilament light polypeptideNF-L; 68 kDa neurofilament protein; Neurofilament triplet L proteinHomo sapiens (human)
Protein phosphatase 1FEC 3.1.3.16; Ca(2+)/calmodulin-dependent protein kinase phosphatase; CaM-kinase phosphatase; CaMKPase; Partner of PIX 2; Protein fem-2 homolog; hFem-2Homo sapiens (human)
Amyloid-beta A4 precursor protein-binding family A member 1Adapter protein X11alpha; Neuron-specific X11 protein; Neuronal Munc18-1-interacting protein 1; Mint-1Homo sapiens (human)
Disks large homolog 1Synapse-associated protein 97; SAP-97; SAP97; hDlgHomo sapiens (human)
NeurobeachinLysosomal-trafficking regulator 2; Protein BCL8BHomo sapiens (human)
Protein phosphatase 1EEC 3.1.3.16; Ca(2+)/calmodulin-dependent protein kinase phosphatase N; CaMKP-N; CaMKP-nucleus; CaMKN; Partner of PIX 1; Partner of PIX-alpha; Partner of PIXAHomo sapiens (human)
Disks large homolog 3Neuroendocrine-DLG; Synapse-associated protein 102; SAP-102; SAP102; XLMRHomo sapiens (human)
Kinesin-like protein KIF17KIF3-related motor proteinHomo sapiens (human)

Compounds (12)

CompoundDescription
CalciumA basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
Orthophosphate
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
MagnesiumA metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION.
SodiumA member of the alkali group of metals. It has the atomic symbol Na, atomic number 11, and atomic weight 23.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Guanosine MonophosphateA guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature.
Guanosine DiphosphateA guanine nucleotide containing two phosphate groups esterified to the sugar moiety.
ifenprodilNMDA receptor antagonist
glutamate
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
cyclic ampAn adenine nucleotide containing one phosphate group which is esterified to both the 3'- and 5'-positions of the sugar moiety. It is a second messenger and a key intracellular regulator, functioning as a mediator of activity for a number of hormones, including epinephrine, glucagon, and ACTH.