Page last updated: 2024-10-06

Activation of ATR in response to replication stress

Proteins (17)

ProteinSynonymsTaxonomy
ATR-interacting proteinATM and Rad3-related-interacting proteinHomo sapiens (human)
Serine/threonine-protein kinase Chk1EC 2.7.11.1; CHK1 checkpoint homolog; Cell cycle checkpoint kinase; Checkpoint kinase-1Homo sapiens (human)
Replication protein A 70 kDa DNA-binding subunitRP-A p70; Replication factor A protein 1; RF-A protein 1; Single-stranded DNA-binding proteinHomo sapiens (human)
M-phase inducer phosphatase 3EC 3.1.3.48; Dual specificity phosphatase Cdc25CHomo sapiens (human)
Replication factor C subunit 5Activator 1 36 kDa subunit; A1 36 kDa subunit; Activator 1 subunit 5; Replication factor C 36 kDa subunit; RF-C 36 kDa subunit; RFC36Homo sapiens (human)
M-phase inducer phosphatase 1EC 3.1.3.48; Dual specificity phosphatase Cdc25AHomo sapiens (human)
Serine/threonine-protein kinase ATREC 2.7.11.1; Ataxia telangiectasia and Rad3-related protein; FRAP-related protein 1Homo sapiens (human)
Cell division control protein 45 homologPORC-PI-1Homo sapiens (human)
Cell cycle checkpoint protein RAD1hRAD1; EC 3.1.11.2; DNA repair exonuclease rad1 homolog; Rad1-like DNA damage checkpoint proteinHomo sapiens (human)
Checkpoint protein HUS1hHUS1Homo sapiens (human)
Cell cycle checkpoint protein RAD17hRad17; RF-C/activator 1 homologHomo sapiens (human)
Replication protein A 32 kDa subunitRP-A p32; Replication factor A protein 2; RF-A protein 2; Replication protein A 34 kDa subunit; RP-A p34Homo sapiens (human)
Replication protein A 14 kDa subunitRP-A p14; Replication factor A protein 3; RF-A protein 3Homo sapiens (human)
Replication factor C subunit 4Activator 1 37 kDa subunit; A1 37 kDa subunit; Activator 1 subunit 4; Replication factor C 37 kDa subunit; RF-C 37 kDa subunit; RFC37Homo sapiens (human)
Replication factor C subunit 2Activator 1 40 kDa subunit; A1 40 kDa subunit; Activator 1 subunit 2; Replication factor C 40 kDa subunit; RF-C 40 kDa subunit; RFC40Homo sapiens (human)
Replication factor C subunit 3Activator 1 38 kDa subunit; A1 38 kDa subunit; Activator 1 subunit 3; Replication factor C 38 kDa subunit; RF-C 38 kDa subunit; RFC38Homo sapiens (human)
ClaspinhClaspinHomo sapiens (human)

Compounds (2)

CompoundDescription
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.