Activated NTRK3 signals through PI3K

Proteins (6)

Protein	Synonyms	Taxonomy
Insulin receptor substrate 1	IRS-1	Homo sapiens (human)
Proto-oncogene tyrosine-protein kinase Src	EC 2.7.10.2; Proto-oncogene c-Src; pp60c-src; p60-Src	Homo sapiens (human)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	PI3-kinase subunit alpha; PI3K-alpha; PI3Kalpha; PtdIns-3-kinase subunit alpha; EC 2.7.1.137; EC 2.7.1.153; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha; PtdIns-3-kinase subunit p110-alpha; p110alpha; Phosphoinositide 3-k	Homo sapiens (human)
NT-3 growth factor receptor	EC 2.7.10.1; GP145-TrkC; Trk-C; Neurotrophic tyrosine kinase receptor type 3; TrkC tyrosine kinase	Homo sapiens (human)
Phosphatidylinositol 3-kinase regulatory subunit alpha	PI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; PI3-kinase subunit p85-alpha; PtdIns-3-kinase regulatory subunit p85-alpha	Homo sapiens (human)
Neurotrophin-3	NT-3; HDNF; Nerve growth factor 2; NGF-2; Neurotrophic factor	Homo sapiens (human)

Compound	Description
adenosine diphosphate	Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
adenosine triphosphate	An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.