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ALKBH3 mediated reversal of alkylation damage

Proteins (4)

ProteinSynonymsTaxonomy
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3EC 1.14.11.54; Alkylated DNA repair protein alkB homolog 3; hABH3; DEPC-1; Prostate cancer antigen 1Homo sapiens (human)
Activating signal cointegrator 1 complex subunit 3EC 3.6.4.12; ASC-1 complex subunit p200; ASC1p200; Helicase, ATP binding 1; Trip4 complex subunit p200Homo sapiens (human)
Activating signal cointegrator 1 complex subunit 1ASC-1 complex subunit p50; Trip4 complex subunit p50Homo sapiens (human)
Activating signal cointegrator 1 complex subunit 2ASC-1 complex subunit p100; Trip4 complex subunit p100Homo sapiens (human)

Compounds (7)

CompoundDescription
Succinate
ironA metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN.
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
formaldehydeA highly reactive aldehyde gas formed by oxidation or incomplete combustion of hydrocarbons. In solution, it has a wide range of uses: in the manufacture of resins and textiles, as a disinfectant, and as a laboratory fixative or preservative. Formaldehyde solution (formalin) is considered a hazardous compound, and its vapor toxic. (From Reynolds, Martindale The Extra Pharmacopoeia, 30th ed, p717)
OxygenAn element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
alpha-Ketoglutarate
acetaldehydeA colorless, flammable liquid used in the manufacture of acetic acid, perfumes, and flavors. It is also an intermediate in the metabolism of alcohol. It has a general narcotic action and also causes irritation of mucous membranes. Large doses may cause death from respiratory paralysis.