A tetrasaccharide linker sequence is required for GAG synthesis

Proteins (5)

Protein	Synonyms	Taxonomy
Beta-1,4-galactosyltransferase 7	Beta-1,4-GalTase 7; Beta4Gal-T7; b4Gal-T7; EC 2.4.1.-; Proteoglycan UDP-galactose:beta-xylose beta1,4-galactosyltransferase I; UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 7; UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 7; U	Homo sapiens (human)
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3	EC 2.4.1.135; Beta-1,3-glucuronyltransferase 3; Glucuronosyltransferase I; GlcAT-I; UDP-GlcUA:Gal beta-1,3-Gal-R glucuronyltransferase; GlcUAT-I	Homo sapiens (human)
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2	EC 2.4.1.135; Beta-1,3-glucuronyltransferase 2; GlcAT-D; UDP-glucuronosyltransferase S; GlcAT-S; Glucuronosyltransferase S	Homo sapiens (human)
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1	EC 2.4.1.135; Beta-1,3-glucuronyltransferase 1; Glucuronosyltransferase P; GlcAT-P; UDP-GlcUA:glycoprotein beta-1,3-glucuronyltransferase; GlcUAT-P	Homo sapiens (human)
Beta-1,3-galactosyltransferase 6	Beta-1,3-GalTase 6; Beta3Gal-T6; Beta3GalT6; EC 2.4.1.134; GAG GalTII; Galactosyltransferase II; Galactosylxylosylprotein 3-beta-galactosyltransferase; UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6	Homo sapiens (human)

Compounds (2)

Compound	Description
uridine diphosphate	A uracil nucleotide containing a pyrophosphate group esterified to C5 of the sugar moiety.
Manganese	A trace element with atomic symbol Mn, atomic number 25, and atomic weight 54.94. It is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver. (From AMA Drug Evaluations Annual 1992, p2035)

Compound

Description

uridine diphosphate

A uracil nucleotide containing a pyrophosphate group esterified to C5 of the sugar moiety.

Manganese

A trace element with atomic symbol Mn, atomic number 25, and atomic weight 54.94. It is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver. (From AMA Drug Evaluations Annual 1992, p2035)