Page last updated: 2024-10-06

4-amino-2-methyl-5-diphosphomethylpyrimidine biosynthesis

Proteins (6)

ProteinSynonymsTaxonomy
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinaseEC 2.7.1.49; EC 2.7.4.7; Hydroxymethylpyrimidine kinase; HMP kinase; Hydroxymethylpyrimidine phosphate kinase; HMP-P kinase; HMP-phosphate kinase; HMPP kinaseBacillus subtilis subsp. subtilis str. 168
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinaseEC 2.7.1.49; EC 2.7.4.7; Hydroxymethylpyrimidine kinase; HMP kinase; Hydroxymethylpyrimidine phosphate kinase; HMP-P kinase; HMP-phosphate kinase; HMPP kinaseEscherichia coli K-12
Phosphomethylpyrimidine synthase, chloroplasticEC 4.1.99.17; Hydroxymethylpyrimidine phosphate synthase; HMP-P synthase; HMP-phosphate synthase; HMPP synthase; Protein PYRIMIDINE REQUIRING; Thiamine biosynthesis protein ThiC; Protein THIAMINE CArabidopsis thaliana (thale cress)
Phosphomethylpyrimidine synthaseEC 4.1.99.17; Hydroxymethylpyrimidine phosphate synthase; HMP-P synthase; HMP-phosphate synthase; HMPP synthase; Thiamine biosynthesis protein ThiCEscherichia coli K-12
Thiamine biosynthetic bifunctional enzyme TH1, chloroplasticArabidopsis thaliana (thale cress)
Phosphomethylpyrimidine synthaseEC 4.1.99.17; Hydroxymethylpyrimidine phosphate synthase; HMP-P synthase; HMP-phosphate synthase; HMPP synthase; Thiamine biosynthesis protein ThiCBacillus subtilis subsp. subtilis str. 168

Compounds (10)

CompoundDescription
hydronium ion
thiamine3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-5-(2- hydroxyethyl)-4-methylthiazolium chloride.
NADH
carbon monoxideCarbon monoxide (CO). A poisonous colorless, odorless, tasteless gas. It combines with hemoglobin to form carboxyhemoglobin, which has no oxygen carrying capacity. The resultant oxygen deprivation causes headache, dizziness, decreased pulse and respiratory rates, unconsciousness, and death. (From Merck Index, 11th ed)
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
formate
5'-deoxyadenosinemain heading DEOXYADENOSINE refers to the 3' cpd
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
s-adenosylmethioninePhysiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed)