Page last updated: 2024-10-06

3-methylbutanol biosynthesis (engineered)

Proteins (9)

ProteinSynonymsTaxonomy
2-isopropylmalate synthaseEC 2.3.3.13; Alpha-IPM synthase; Alpha-isopropylmalate synthaseEscherichia coli K-12
S-(hydroxymethyl)glutathione dehydrogenaseEC 1.1.1.284; Alcohol dehydrogenase SFA; 1.1.1.1; Glutathione-dependent formaldehyde dehydrogenase; FALDH; FDH; FLD; GSH-FDH; 1.1.1.-Saccharomyces cerevisiae S288C
Alcohol dehydrogenase 1EC 1.1.1.1; Alcohol dehydrogenase I; YADH-1Saccharomyces cerevisiae S288C
Alcohol dehydrogenase 2EC 1.1.1.1; Alcohol dehydrogenase II; YADH-2Saccharomyces cerevisiae S288C
Alcohol dehydrogenase 3, mitochondrialEC 1.1.1.1; Alcohol dehydrogenase III; YADH-3Saccharomyces cerevisiae S288C
Alcohol dehydrogenase 4EC 1.1.1.1; Alcohol dehydrogenase IV; ADHIVSaccharomyces cerevisiae S288C
Alcohol dehydrogenase 5EC 1.1.1.1; Alcohol dehydrogenase VSaccharomyces cerevisiae S288C
Thiamine metabolism regulatory protein THI3EC 4.1.1.72; Keto isocaproate decarboxylase 1; Thiamine pyrophosphate-dependent 2-oxo-acid decarboxylase; 2ODCSaccharomyces cerevisiae S288C
Alpha-ketoisovalerate decarboxylaseLactococcus lactis subsp. lactis

Compounds (13)

CompoundDescription
hydronium ion
Thiamine PyrophosphateThe coenzyme form of Vitamin B1 present in many animal tissues. It is a required intermediate in the PYRUVATE DEHYDROGENASE COMPLEX and the KETOGLUTARATE DEHYDROGENASE COMPLEX.
NADH
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
MagnesiumA metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
isovalerylaldehydestructure in Merck Index, 9th ed, #5093
nadA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
2-keto-4-methylvalerate
alpha-keto-isovaleric acid
Coenzyme A
isopentyl alcoholRN given refers to unlabeled parent cpd
Acetyl Coenzyme AAcetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.