Pathways > 3-methylbutanol biosynthesis (engineered)
Page last updated: 2024-10-06
3-methylbutanol biosynthesis (engineered)
Proteins (9)
| Protein | Synonyms | Taxonomy |
|---|
| 2-isopropylmalate synthase | EC 2.3.3.13; Alpha-IPM synthase; Alpha-isopropylmalate synthase | Escherichia coli K-12 |
| S-(hydroxymethyl)glutathione dehydrogenase | EC 1.1.1.284; Alcohol dehydrogenase SFA; 1.1.1.1; Glutathione-dependent formaldehyde dehydrogenase; FALDH; FDH; FLD; GSH-FDH; 1.1.1.- | Saccharomyces cerevisiae S288C |
| Alcohol dehydrogenase 1 | EC 1.1.1.1; Alcohol dehydrogenase I; YADH-1 | Saccharomyces cerevisiae S288C |
| Alcohol dehydrogenase 2 | EC 1.1.1.1; Alcohol dehydrogenase II; YADH-2 | Saccharomyces cerevisiae S288C |
| Alcohol dehydrogenase 3, mitochondrial | EC 1.1.1.1; Alcohol dehydrogenase III; YADH-3 | Saccharomyces cerevisiae S288C |
| Alcohol dehydrogenase 4 | EC 1.1.1.1; Alcohol dehydrogenase IV; ADHIV | Saccharomyces cerevisiae S288C |
| Alcohol dehydrogenase 5 | EC 1.1.1.1; Alcohol dehydrogenase V | Saccharomyces cerevisiae S288C |
| Thiamine metabolism regulatory protein THI3 | EC 4.1.1.72; Keto isocaproate decarboxylase 1; Thiamine pyrophosphate-dependent 2-oxo-acid decarboxylase; 2ODC | Saccharomyces cerevisiae S288C |
| Alpha-ketoisovalerate decarboxylase | | Lactococcus lactis subsp. lactis |
Compounds (13)
| Compound | Description |
|---|
| hydronium ion | |
| Thiamine Pyrophosphate | The coenzyme form of Vitamin B1 present in many animal tissues. It is a required intermediate in the PYRUVATE DEHYDROGENASE COMPLEX and the KETOGLUTARATE DEHYDROGENASE COMPLEX. |
| NADH | |
| Carbon Dioxide | A colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals. |
| Magnesium | A metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION. |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| isovalerylaldehyde | structure in Merck Index, 9th ed, #5093 |
| nad | A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed) |
| 2-keto-4-methylvalerate | |
| alpha-keto-isovaleric acid | |
| Coenzyme A | |
| isopentyl alcohol | RN given refers to unlabeled parent cpd |
| Acetyl Coenzyme A | Acetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent. |