zopolrestat has been researched along with Fibrosis in 1 studies
zopolrestat: structure given in first source
Fibrosis: Any pathological condition where fibrous connective tissue invades any organ, usually as a consequence of inflammation or other injury.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The combination of peritoneal exposure to dialysis fluids and administration of zopolrestat, a newly developed inhibitor of aldose reductase activity, resulted in less fibrosis and fewer peritoneal vessels than exposure to dialysis fluids only, in a long-term exposure model in the rat." | 3.73 | Effects of inhibition of the polyol pathway during chronic peritoneal exposure to a dialysis solution. ( Aberra, M; Aten, J; Deira, G; Dragt, CA; Krediet, RT; van Westrhenen, R, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| van Westrhenen, R | 1 |
| Aten, J | 1 |
| Aberra, M | 1 |
| Dragt, CA | 1 |
| Deira, G | 1 |
| Krediet, RT | 1 |
1 other study available for zopolrestat and Fibrosis
| Article | Year |
|---|---|
Effects of inhibition of the polyol pathway during chronic peritoneal exposure to a dialysis solution.
Topics: Aldehyde Reductase; Animals; Benzothiazoles; Dialysis Solutions; Enzyme Inhibitors; Fibrosis; Glucos | 2005 |