Page last updated: 2024-10-21

zopolrestat and Diabetic Neuropathies

zopolrestat has been researched along with Diabetic Neuropathies in 3 studies

zopolrestat: structure given in first source

Diabetic Neuropathies: Peripheral, autonomic, and cranial nerve disorders that are associated with DIABETES MELLITUS. These conditions usually result from diabetic microvascular injury involving small blood vessels that supply nerves (VASA NERVORUM). Relatively common conditions which may be associated with diabetic neuropathy include third nerve palsy (see OCULOMOTOR NERVE DISEASES); MONONEUROPATHY; mononeuropathy multiplex; diabetic amyotrophy; a painful POLYNEUROPATHY; autonomic neuropathy; and thoracoabdominal neuropathy. (From Adams et al., Principles of Neurology, 6th ed, p1325)

Research Excerpts

ExcerptRelevanceReference
"We have developed an animal model of diabetic autonomic neuropathy characterized by neuroaxonal dystrophy involving ileal mesenteric nerves and prevertebral sympathetic superior mesenteric ganglia (SMG) in chronic streptozocin-diabetic rats."1.30Effect of sorbitol dehydrogenase inhibition on experimental diabetic autonomic neuropathy. ( Beaudet, LN; Dorsey, DA; Ido, Y; Plurad, SB; Schmidt, RE; Williamson, JR, 1998)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Johnson, BF1
Nesto, RW1
Pfeifer, MA1
Slater, WR1
Vinik, AI1
Chyun, DA1
Law, G1
Wackers, FJ1
Young, LH1
Schmidt, RE1
Dorsey, DA1
Beaudet, LN1
Plurad, SB1
Williamson, JR1
Ido, Y1
Arezzo, JC1

Reviews

1 review available for zopolrestat and Diabetic Neuropathies

ArticleYear
New developments in the diagnosis of diabetic neuropathy.
    The American journal of medicine, 1999, Aug-30, Volume: 107, Issue:2B

    Topics: Aldehyde Reductase; Axons; Benzothiazoles; Biopsy; Controlled Clinical Trials as Topic; Diabetic Neu

1999

Trials

1 trial available for zopolrestat and Diabetic Neuropathies

ArticleYear
Cardiac abnormalities in diabetic patients with neuropathy: effects of aldose reductase inhibitor administration.
    Diabetes care, 2004, Volume: 27, Issue:2

    Topics: Aldehyde Reductase; Benzothiazoles; Cardiac Output; Diabetes Mellitus, Type 1; Diabetes Mellitus, Ty

2004

Other Studies

1 other study available for zopolrestat and Diabetic Neuropathies

ArticleYear
Effect of sorbitol dehydrogenase inhibition on experimental diabetic autonomic neuropathy.
    Journal of neuropathology and experimental neurology, 1998, Volume: 57, Issue:12

    Topics: Animals; Autonomic Nervous System Diseases; Benzothiazoles; Diabetic Neuropathies; Drug Evaluation,

1998