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zopolrestat and Complications of Diabetes Mellitus

zopolrestat has been researched along with Complications of Diabetes Mellitus in 2 studies

zopolrestat: structure given in first source

Research Excerpts

ExcerptRelevanceReference
"45 mug equiv/g, respectively, when dosed with [(14)C]lidorestat at 10 mg/kg po)."1.33Discovery of 3-[(4,5,7-trifluorobenzothiazol-2-yl)methyl]indole-N-acetic acid (lidorestat) and congeners as highly potent and selective inhibitors of aldose reductase for treatment of chronic diabetic complications. ( Dicioccio, AT; Geraci, LS; Gunn, DE; Jacot, JL; Jones, JH; Jones, ML; Mitschler, A; Petrova, T; Podjarny, AD; Sawicki, DR; Sredy, J; Van Zandt, MC, 2005)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Van Zandt, MC1
Jones, ML1
Gunn, DE1
Geraci, LS1
Jones, JH1
Sawicki, DR1
Sredy, J1
Jacot, JL1
Dicioccio, AT1
Petrova, T1
Mitschler, A1
Podjarny, AD1
Kotani, T1
Nagaki, Y1
Ishii, A1
Konishi, Y1
Yago, H1
Suehiro, S1
Okukado, N1
Okamoto, K1

Other Studies

2 other studies available for zopolrestat and Complications of Diabetes Mellitus

ArticleYear
Discovery of 3-[(4,5,7-trifluorobenzothiazol-2-yl)methyl]indole-N-acetic acid (lidorestat) and congeners as highly potent and selective inhibitors of aldose reductase for treatment of chronic diabetic complications.
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: Aldehyde Reductase; Animals; Cataract; Chronic Disease; Crystallography, X-Ray; Diabetes Complicatio

2005
Highly selective aldose reductase inhibitors. 3. Structural diversity of 3-(arylmethyl)-2,4,5-trioxoimidazolidine-1-acetic acids.
    Journal of medicinal chemistry, 1997, Feb-28, Volume: 40, Issue:5

    Topics: Acetates; Aldehyde Reductase; Animals; Benzothiazoles; Diabetes Complications; Enzyme Inhibitors; Hu

1997