zopolrestat has been researched along with Complications of Diabetes Mellitus in 2 studies
zopolrestat: structure given in first source
| Excerpt | Relevance | Reference |
|---|---|---|
| "45 mug equiv/g, respectively, when dosed with [(14)C]lidorestat at 10 mg/kg po)." | 1.33 | Discovery of 3-[(4,5,7-trifluorobenzothiazol-2-yl)methyl]indole-N-acetic acid (lidorestat) and congeners as highly potent and selective inhibitors of aldose reductase for treatment of chronic diabetic complications. ( Dicioccio, AT; Geraci, LS; Gunn, DE; Jacot, JL; Jones, JH; Jones, ML; Mitschler, A; Petrova, T; Podjarny, AD; Sawicki, DR; Sredy, J; Van Zandt, MC, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Van Zandt, MC | 1 |
| Jones, ML | 1 |
| Gunn, DE | 1 |
| Geraci, LS | 1 |
| Jones, JH | 1 |
| Sawicki, DR | 1 |
| Sredy, J | 1 |
| Jacot, JL | 1 |
| Dicioccio, AT | 1 |
| Petrova, T | 1 |
| Mitschler, A | 1 |
| Podjarny, AD | 1 |
| Kotani, T | 1 |
| Nagaki, Y | 1 |
| Ishii, A | 1 |
| Konishi, Y | 1 |
| Yago, H | 1 |
| Suehiro, S | 1 |
| Okukado, N | 1 |
| Okamoto, K | 1 |
2 other studies available for zopolrestat and Complications of Diabetes Mellitus
| Article | Year |
|---|---|
Discovery of 3-[(4,5,7-trifluorobenzothiazol-2-yl)methyl]indole-N-acetic acid (lidorestat) and congeners as highly potent and selective inhibitors of aldose reductase for treatment of chronic diabetic complications.
Topics: Aldehyde Reductase; Animals; Cataract; Chronic Disease; Crystallography, X-Ray; Diabetes Complicatio | 2005 |
Highly selective aldose reductase inhibitors. 3. Structural diversity of 3-(arylmethyl)-2,4,5-trioxoimidazolidine-1-acetic acids.
Topics: Acetates; Aldehyde Reductase; Animals; Benzothiazoles; Diabetes Complications; Enzyme Inhibitors; Hu | 1997 |