zopolrestat has been researched along with Cataract in 2 studies
zopolrestat: structure given in first source
Cataract: Partial or complete opacity on or in the lens or capsule of one or both eyes, impairing vision or causing blindness. The many kinds of cataract are classified by their morphology (size, shape, location) or etiology (cause and time of occurrence). (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aldose reductase inhibitor, Zopolrestat, reduced proteinuria and albuminuria in streptozocin-induced diabetic rats compared with both untreated diabetic and age-matched controls." | 7.69 | Zopolrestat prevention of proteinuria, albuminuria and cataractogenesis in diabetes mellitus. ( Beyer-Mears, A; Cruz, E; Diecke, FP; Mistry, K, 1996) |
| "The aldose reductase inhibitor, Zopolrestat, reduced proteinuria and albuminuria in streptozocin-induced diabetic rats compared with both untreated diabetic and age-matched controls." | 3.69 | Zopolrestat prevention of proteinuria, albuminuria and cataractogenesis in diabetes mellitus. ( Beyer-Mears, A; Cruz, E; Diecke, FP; Mistry, K, 1996) |
| "45 mug equiv/g, respectively, when dosed with [(14)C]lidorestat at 10 mg/kg po)." | 1.33 | Discovery of 3-[(4,5,7-trifluorobenzothiazol-2-yl)methyl]indole-N-acetic acid (lidorestat) and congeners as highly potent and selective inhibitors of aldose reductase for treatment of chronic diabetic complications. ( Dicioccio, AT; Geraci, LS; Gunn, DE; Jacot, JL; Jones, JH; Jones, ML; Mitschler, A; Petrova, T; Podjarny, AD; Sawicki, DR; Sredy, J; Van Zandt, MC, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Van Zandt, MC | 1 |
| Jones, ML | 1 |
| Gunn, DE | 1 |
| Geraci, LS | 1 |
| Jones, JH | 1 |
| Sawicki, DR | 1 |
| Sredy, J | 1 |
| Jacot, JL | 1 |
| Dicioccio, AT | 1 |
| Petrova, T | 1 |
| Mitschler, A | 1 |
| Podjarny, AD | 1 |
| Beyer-Mears, A | 1 |
| Mistry, K | 1 |
| Diecke, FP | 1 |
| Cruz, E | 1 |
2 other studies available for zopolrestat and Cataract
| Article | Year |
|---|---|
Discovery of 3-[(4,5,7-trifluorobenzothiazol-2-yl)methyl]indole-N-acetic acid (lidorestat) and congeners as highly potent and selective inhibitors of aldose reductase for treatment of chronic diabetic complications.
Topics: Aldehyde Reductase; Animals; Cataract; Chronic Disease; Crystallography, X-Ray; Diabetes Complicatio | 2005 |
Zopolrestat prevention of proteinuria, albuminuria and cataractogenesis in diabetes mellitus.
Topics: Albuminuria; Aldehyde Reductase; Animals; Benzothiazoles; Cataract; Chromatography, Gas; Diabetes Me | 1996 |