zopiclone has been researched along with Sleep Wake Disorders in 23 studies
zopiclone: S(+)-enantiomer of racemic zopiclone; azabicyclo(4.3.0)nonane; a nonbenzodiazepine; one of the so-called of Z drugs (zopiclone, eszopiclone, zolpidem, and zaleplon) for which there is some correlation with tumors; was term of zopiclone 2004-2007
zopiclone : A pyrrolo[3,4-b]pyrazine compound having a 4-methylpiperazine-1-carboxyl group at the 5-position, a 5-chloropyridin-2-yl group at the 6-position and an oxo-substituent at the 7-position.
Sleep Wake Disorders: Abnormal sleep-wake schedule or pattern associated with the CIRCADIAN RHYTHM which affect the length, timing, and/or rigidity of the sleep-wake cycle relative to the day-night cycle.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The clinical and polysomnographical effects of zopiclone were evaluated in 41 patients with fibromyalgia in a double blind controlled study." | 9.07 | Zopiclone in the treatment of sleep abnormalities in fibromyalgia. ( Andreasen, A; Drewes, AM; Jennum, P; Nielsen, KD, 1991) |
| "The clinical and polysomnographical effects of zopiclone were evaluated in 41 patients with fibromyalgia in a double blind controlled study." | 5.07 | Zopiclone in the treatment of sleep abnormalities in fibromyalgia. ( Andreasen, A; Drewes, AM; Jennum, P; Nielsen, KD, 1991) |
| "Sleep disturbance is common in dementia and often treated with Z-drugs (zopiclone, zaleplon, and zolpidem)." | 3.96 | Adverse effects of Z-drugs for sleep disturbance in people living with dementia: a population-based cohort study. ( Aldus, C; Arthur, A; Ballard, C; Boyd, PJ; Fox, C; Howard, R; Loke, YK; Maidment, I; Richardson, K; Savva, GM; Steel, N, 2020) |
| "Zopiclone use was assessed to provide an indirect evaluation of the possible hypnotic activity of both treatments." | 2.70 | Efficacy and safety of tianeptine in major depression: evidence from a 3-month controlled clinical trial versus paroxetine. ( Azoulay, P; Septien, L; Waintraub, L, 2002) |
| " The results indicate that zopiclone is an active hypnotic compound, comparable in its effects to those of nitrazepam, the higher dosage being best adapted to the type of patients included in the study." | 2.65 | Comparison of nitrazepam and zopiclone in psychiatric patients. ( Brun, JP; Dreyfus, JF; Pull, CB, 1982) |
| "Two syndromes, hypersomnia and REM sleep behavior disorder (RBD), are increasingly recognized as harbingers of the core PD motor syndrome." | 2.48 | Sleep disorders in Parkinson's disease: many causes, few therapeutic options. ( Diederich, NJ; McIntyre, DJ, 2012) |
| "For the symptomatic drug treatment of insomnias, the specific metabolic and pharmacokinetic, as well as possible interactions, should be considered." | 2.42 | [Drug treatment of sleep disorders in the elderly]. ( Wiegand, MH, 2003) |
| "This pilot study suggests that a higher dosage of zolpidem (> 10 mg/d) is the key risk predictor for CSBs." | 1.36 | Risk predictors for hypnosedative-related complex sleep behaviors: a retrospective, cross-sectional pilot study. ( Chen, HC; Hwang, TJ; Liao, SC; Lin, YT; Ni, HC, 2010) |
| "While one patient had a polysubstance abuse there was no evidence for an abuse history in the other patient." | 1.30 | [Dependency of non-benzodiazepine hypnotics. Two case reports]. ( Antonijevic, IA; Sonntag, A; Steiger, A; Ströhle, A, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.35) | 18.7374 |
| 1990's | 5 (21.74) | 18.2507 |
| 2000's | 10 (43.48) | 29.6817 |
| 2010's | 6 (26.09) | 24.3611 |
| 2020's | 1 (4.35) | 2.80 |
| Authors | Studies |
|---|---|
| Richardson, K | 1 |
| Loke, YK | 1 |
| Fox, C | 1 |
| Maidment, I | 1 |
| Howard, R | 1 |
| Steel, N | 1 |
| Arthur, A | 1 |
| Boyd, PJ | 1 |
| Aldus, C | 1 |
| Ballard, C | 1 |
| Savva, GM | 1 |
| Watari, T | 1 |
| Tokuda, Y | 1 |
| Ferentinos, P | 1 |
| Paparrigopoulos, T | 1 |
| Sivertsen, B | 2 |
| Nordhus, IH | 2 |
| Bjorvatn, B | 2 |
| Pallesen, S | 2 |
| Hwang, TJ | 1 |
| Ni, HC | 1 |
| Chen, HC | 1 |
| Lin, YT | 1 |
| Liao, SC | 1 |
| Diederich, NJ | 1 |
| McIntyre, DJ | 1 |
| Peacey, J | 1 |
| Miller, H | 1 |
| Huthwaite, MA | 1 |
| Romans, SE | 1 |
| Verster, JC | 1 |
| Roth, T | 1 |
| Wiegand, MH | 1 |
| Omvik, S | 1 |
| Miller, MC | 1 |
| Zlotos, DP | 1 |
| Alexandre, C | 1 |
| Dordal, A | 1 |
| Aixendri, R | 1 |
| Guzman, A | 1 |
| Hamon, M | 1 |
| Adrien, J | 1 |
| Pull, CB | 1 |
| Dreyfus, JF | 1 |
| Brun, JP | 1 |
| Li, S | 1 |
| Wang, C | 1 |
| Shapiro, CM | 1 |
| MacFarlane, JG | 1 |
| MacLean, AW | 1 |
| Drewes, AM | 2 |
| Bjerregård, K | 1 |
| Taagholt, SJ | 1 |
| Svendsen, L | 1 |
| Nielsen, KD | 2 |
| Ströhle, A | 1 |
| Antonijevic, IA | 1 |
| Steiger, A | 1 |
| Sonntag, A | 1 |
| Levin, IaI | 1 |
| Gasanov, RL | 1 |
| Kolobov, SV | 1 |
| Waintraub, L | 1 |
| Septien, L | 1 |
| Azoulay, P | 1 |
| Georgiev, V | 1 |
| Andreasen, A | 1 |
| Jennum, P | 1 |
5 reviews available for zopiclone and Sleep Wake Disorders
| Article | Year |
|---|---|
Sleep disorders in Parkinson's disease: many causes, few therapeutic options.
Topics: Azabicyclo Compounds; Disorders of Excessive Somnolence; Humans; Hypnotics and Sedatives; Parkinson | 2012 |
Gender differences in highway driving performance after administration of sleep medication: a review of the literature.
Topics: Acetamides; Automobile Driving; Azabicyclo Compounds; Environment Design; Female; Flurazepam; Humans | 2012 |
[Drug treatment of sleep disorders in the elderly].
Topics: Acetamides; Aged; Aged, 80 and over; Antidepressive Agents; Antipsychotic Agents; Azabicyclo Compoun | 2003 |
[Drugs in the pipeline].
Topics: Animals; Azabicyclo Compounds; GABA-A Receptor Agonists; Humans; Hypnotics and Sedatives; Mice; Mice | 2007 |
(S)-Zopiclone Sepracor.
Topics: Animals; Azabicyclo Compounds; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic | 2001 |
6 trials available for zopiclone and Sleep Wake Disorders
| Article | Year |
|---|---|
Comparison of nitrazepam and zopiclone in psychiatric patients.
Topics: Adolescent; Adult; Aged; Azabicyclo Compounds; Clinical Trials as Topic; Double-Blind Method; Emotio | 1982 |
A comparative study of imovane and estazolam treatment on sleep disturbances.
Topics: Adolescent; Adult; Aged; Azabicyclo Compounds; Estazolam; Female; Humans; Hypnotics and Sedatives; M | 1995 |
Alleviating sleep-related discontinuance symptoms associated with benzodiazepine withdrawal: a new approach.
Topics: Adult; Azabicyclo Compounds; Benzodiazepines; Female; Humans; Hypnotics and Sedatives; Male; Middle | 1993 |
Zopiclone as night medication in rheumatoid arthritis.
Topics: Adult; Arthritis, Rheumatoid; Azabicyclo Compounds; Electroencephalography; Female; Humans; Hypnotic | 1998 |
Efficacy and safety of tianeptine in major depression: evidence from a 3-month controlled clinical trial versus paroxetine.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Antidepressive Age | 2002 |
Zopiclone in the treatment of sleep abnormalities in fibromyalgia.
Topics: Aged; Azabicyclo Compounds; Female; Fibromyalgia; Humans; Hypnotics and Sedatives; Middle Aged; Pipe | 1991 |
12 other studies available for zopiclone and Sleep Wake Disorders
| Article | Year |
|---|---|
Adverse effects of Z-drugs for sleep disturbance in people living with dementia: a population-based cohort study.
Topics: Acetamides; Aged, 80 and over; Azabicyclo Compounds; Cohort Studies; Dementia; Female; Humans; Male; | 2020 |
Drug-induced hemichorea.
Topics: Aged, 80 and over; Antipsychotic Agents; Azabicyclo Compounds; Chorea; Drug Administration Schedule; | 2015 |
Zopiclone and sleepwalking.
Topics: Azabicyclo Compounds; Female; Humans; Hypnotics and Sedatives; Middle Aged; Piperazines; Schizophren | 2009 |
Sleep problems in general practice: a national survey of assessment and treatment routines of general practitioners in Norway.
Topics: Azabicyclo Compounds; Benzodiazepines; Brain; Drug Prescriptions; Female; Humans; Hypnotics and Seda | 2010 |
Risk predictors for hypnosedative-related complex sleep behaviors: a retrospective, cross-sectional pilot study.
Topics: Antidepressive Agents; Azabicyclo Compounds; Benzodiazepines; Cross-Sectional Studies; Female; Human | 2010 |
Sleep medication in acute psychiatric illness: patient's knowledge and prescription patterns in New Zealand.
Topics: Acute Disease; Adult; Azabicyclo Compounds; Cross-Sectional Studies; Female; Health Knowledge, Attit | 2012 |
Sleeping pills without regrets. They've long been the risky quick fixes of sleep medicine. Soon some sleeping pills may be sold as long-term solutions.
Topics: Acetamides; Age Factors; Azabicyclo Compounds; Benzodiazepines; Humans; Hypnotics and Sedatives; Pip | 2004 |
[Sleep disorders in elderly patients who take hypnotics on a regular basis].
Topics: Aged; Azabicyclo Compounds; Female; Humans; Hypnotics and Sedatives; Male; Nocturnal Myoclonus Syndr | 2004 |
Questions & answers. I have chronic problems sleeping. I have heard about a new sleep medicine called Lunesta. Does it have any advantages over other sleep drugs?
Topics: Azabicyclo Compounds; Humans; Hypnotics and Sedatives; Piperazines; Sleep Wake Disorders | 2005 |
Sleep-stabilizing effects of E-6199, compared to zopiclone, zolpidem and THIP in mice.
Topics: Animals; Azabicyclo Compounds; Electroencephalography; Hypnotics and Sedatives; Isoxazoles; Mice; Pi | 2008 |
[Dependency of non-benzodiazepine hypnotics. Two case reports].
Topics: Adult; Azabicyclo Compounds; Benzodiazepines; Depression; Humans; Hypnotics and Sedatives; Male; Mid | 1999 |
[Imovan in therapy of sleep disorders in patients with cerebral stroke].
Topics: Azabicyclo Compounds; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Piperazines; Polys | 2000 |