zopiclone has been researched along with Pregnancy in 8 studies
zopiclone: S(+)-enantiomer of racemic zopiclone; azabicyclo(4.3.0)nonane; a nonbenzodiazepine; one of the so-called of Z drugs (zopiclone, eszopiclone, zolpidem, and zaleplon) for which there is some correlation with tumors; was term of zopiclone 2004-2007
zopiclone : A pyrrolo[3,4-b]pyrazine compound having a 4-methylpiperazine-1-carboxyl group at the 5-position, a 5-chloropyridin-2-yl group at the 6-position and an oxo-substituent at the 7-position.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The Motherisk Program, the Toronto Teratogen Information Service, prospectively collected and followed up 40 women exposed to zopiclone during pregnancy." | 7.70 | Pregnancy outcome following first-trimester exposure to zopiclone: a prospective controlled cohort study. ( Diav-Citrin, O; Koren, G; Lucarelli, K; Okotore, B, 1999) |
| "The Motherisk Program, the Toronto Teratogen Information Service, prospectively collected and followed up 40 women exposed to zopiclone during pregnancy." | 3.70 | Pregnancy outcome following first-trimester exposure to zopiclone: a prospective controlled cohort study. ( Diav-Citrin, O; Koren, G; Lucarelli, K; Okotore, B, 1999) |
| " Plasma kinetics of ZD are generally well described by a two-compartment open model; in man, terminal half-life is 4-5 h; total body clearance is large (300 ml/mn), renal clearance very low (10 ml/min)." | 1.27 | Pharmacokinetics and metabolism of zopiclone. ( Dreyfus, JF; Gaillot, J; Heusse, D; Hougton, GW; Marc Aurele, J, 1983) |
| " Plasma kinetics of ZD are generally well described by a two-compartment open model; in man, terminal half-life is 4-5 h; total body clearance is large (300 ml/mn), renal clearance very low (10 ml/min)." | 1.26 | Pharmacokinetics and metabolism of zopiclone. ( Dreyfus, JF; Gaillot, J; Heusse, D; Hougton, GW; Marc Aurele, J, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (62.50) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wikner, BN | 1 |
| Källén, B | 1 |
| Gaillot, J | 2 |
| Heusse, D | 2 |
| Hougton, GW | 2 |
| Marc Aurele, J | 2 |
| Dreyfus, JF | 2 |
| Tokunaga, T | 2 |
| Morishita, H | 2 |
| Kushiku, K | 2 |
| Abe, M | 2 |
| Matsuki, J | 2 |
| Inoue, T | 2 |
| Furukawa, T | 2 |
| Diav-Citrin, O | 2 |
| Okotore, B | 2 |
| Lucarelli, K | 2 |
| Koren, G | 2 |
| Kawamoto, H | 2 |
| Umemura, T | 1 |
| Yamaguchi, K | 1 |
| Watanabe, M | 1 |
| Esaki, K | 1 |
| Yanagita, T | 1 |
8 other studies available for zopiclone and Pregnancy
| Article | Year |
|---|---|
Are hypnotic benzodiazepine receptor agonists teratogenic in humans?
Topics: Abnormalities, Drug-Induced; Acetamides; Adult; Azabicyclo Compounds; Congenital Abnormalities; Fema | 2011 |
Pharmacokinetics and metabolism of zopiclone.
Topics: Administration, Oral; Aged; Aging; Animals; Autoradiography; Azabicyclo Compounds; Biotransformation | 1983 |
[Pharmacodynamic effects of zopiclone].
Topics: Animals; Azabicyclo Compounds; Bile; Diaphragm; Female; Gastrointestinal Motility; Guinea Pigs; Hemo | 1983 |
Pharmacokinetics and metabolism of zopiclone.
Topics: Administration, Oral; Adult; Aged; Aging; Animals; Autoradiography; Azabicyclo Compounds; Dogs; Fema | 1982 |
Pregnancy outcome following first-trimester exposure to zopiclone: a prospective controlled cohort study.
Topics: Abnormalities, Drug-Induced; Adult; Azabicyclo Compounds; Case-Control Studies; Female; Gestational | 1999 |
Zopiclone use during pregnancy.
Topics: Abnormalities, Drug-Induced; Adult; Azabicyclo Compounds; Female; Humans; Hypnotics and Sedatives; P | 2000 |
Pharmacodynamic effects of the sleep inducer zopiclone.
Topics: Animals; Azabicyclo Compounds; Blood Pressure; Diaphragm; Electrocardiography; Female; Gastrointesti | 1987 |
Influence of zopiclone on male reproductivity in rats.
Topics: Animals; Azabicyclo Compounds; Body Weight; Female; Genitalia, Male; Hypnotics and Sedatives; Male; | 1987 |