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zopiclone and Pregnancy

zopiclone has been researched along with Pregnancy in 8 studies

zopiclone: S(+)-enantiomer of racemic zopiclone; azabicyclo(4.3.0)nonane; a nonbenzodiazepine; one of the so-called of Z drugs (zopiclone, eszopiclone, zolpidem, and zaleplon) for which there is some correlation with tumors; was term of zopiclone 2004-2007
zopiclone : A pyrrolo[3,4-b]pyrazine compound having a 4-methylpiperazine-1-carboxyl group at the 5-position, a 5-chloropyridin-2-yl group at the 6-position and an oxo-substituent at the 7-position.

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
"The Motherisk Program, the Toronto Teratogen Information Service, prospectively collected and followed up 40 women exposed to zopiclone during pregnancy."7.70Pregnancy outcome following first-trimester exposure to zopiclone: a prospective controlled cohort study. ( Diav-Citrin, O; Koren, G; Lucarelli, K; Okotore, B, 1999)
"The Motherisk Program, the Toronto Teratogen Information Service, prospectively collected and followed up 40 women exposed to zopiclone during pregnancy."3.70Pregnancy outcome following first-trimester exposure to zopiclone: a prospective controlled cohort study. ( Diav-Citrin, O; Koren, G; Lucarelli, K; Okotore, B, 1999)
" Plasma kinetics of ZD are generally well described by a two-compartment open model; in man, terminal half-life is 4-5 h; total body clearance is large (300 ml/mn), renal clearance very low (10 ml/min)."1.27Pharmacokinetics and metabolism of zopiclone. ( Dreyfus, JF; Gaillot, J; Heusse, D; Hougton, GW; Marc Aurele, J, 1983)
" Plasma kinetics of ZD are generally well described by a two-compartment open model; in man, terminal half-life is 4-5 h; total body clearance is large (300 ml/mn), renal clearance very low (10 ml/min)."1.26Pharmacokinetics and metabolism of zopiclone. ( Dreyfus, JF; Gaillot, J; Heusse, D; Hougton, GW; Marc Aurele, J, 1982)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19905 (62.50)18.7374
1990's1 (12.50)18.2507
2000's1 (12.50)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wikner, BN1
Källén, B1
Gaillot, J2
Heusse, D2
Hougton, GW2
Marc Aurele, J2
Dreyfus, JF2
Tokunaga, T2
Morishita, H2
Kushiku, K2
Abe, M2
Matsuki, J2
Inoue, T2
Furukawa, T2
Diav-Citrin, O2
Okotore, B2
Lucarelli, K2
Koren, G2
Kawamoto, H2
Umemura, T1
Yamaguchi, K1
Watanabe, M1
Esaki, K1
Yanagita, T1

Other Studies

8 other studies available for zopiclone and Pregnancy

ArticleYear
Are hypnotic benzodiazepine receptor agonists teratogenic in humans?
    Journal of clinical psychopharmacology, 2011, Volume: 31, Issue:3

    Topics: Abnormalities, Drug-Induced; Acetamides; Adult; Azabicyclo Compounds; Congenital Abnormalities; Fema

2011
Pharmacokinetics and metabolism of zopiclone.
    Pharmacology, 1983, Volume: 27 Suppl 2

    Topics: Administration, Oral; Aged; Aging; Animals; Autoradiography; Azabicyclo Compounds; Biotransformation

1983
[Pharmacodynamic effects of zopiclone].
    Igaku kenkyu. Acta medica, 1983, Volume: 53, Issue:4

    Topics: Animals; Azabicyclo Compounds; Bile; Diaphragm; Female; Gastrointestinal Motility; Guinea Pigs; Hemo

1983
Pharmacokinetics and metabolism of zopiclone.
    International pharmacopsychiatry, 1982, Volume: 17 Suppl 2

    Topics: Administration, Oral; Adult; Aged; Aging; Animals; Autoradiography; Azabicyclo Compounds; Dogs; Fema

1982
Pregnancy outcome following first-trimester exposure to zopiclone: a prospective controlled cohort study.
    American journal of perinatology, 1999, Volume: 16, Issue:4

    Topics: Abnormalities, Drug-Induced; Adult; Azabicyclo Compounds; Case-Control Studies; Female; Gestational

1999
Zopiclone use during pregnancy.
    Canadian family physician Medecin de famille canadien, 2000, Volume: 46

    Topics: Abnormalities, Drug-Induced; Adult; Azabicyclo Compounds; Female; Humans; Hypnotics and Sedatives; P

2000
Pharmacodynamic effects of the sleep inducer zopiclone.
    Arzneimittel-Forschung, 1987, Volume: 37, Issue:12

    Topics: Animals; Azabicyclo Compounds; Blood Pressure; Diaphragm; Electrocardiography; Female; Gastrointesti

1987
Influence of zopiclone on male reproductivity in rats.
    Research communications in chemical pathology and pharmacology, 1987, Volume: 56, Issue:2

    Topics: Animals; Azabicyclo Compounds; Body Weight; Female; Genitalia, Male; Hypnotics and Sedatives; Male;

1987