zopiclone has been researched along with Parkinson Disease in 2 studies
zopiclone: S(+)-enantiomer of racemic zopiclone; azabicyclo(4.3.0)nonane; a nonbenzodiazepine; one of the so-called of Z drugs (zopiclone, eszopiclone, zolpidem, and zaleplon) for which there is some correlation with tumors; was term of zopiclone 2004-2007
zopiclone : A pyrrolo[3,4-b]pyrazine compound having a 4-methylpiperazine-1-carboxyl group at the 5-position, a 5-chloropyridin-2-yl group at the 6-position and an oxo-substituent at the 7-position.
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Two syndromes, hypersomnia and REM sleep behavior disorder (RBD), are increasingly recognized as harbingers of the core PD motor syndrome." | 2.48 | Sleep disorders in Parkinson's disease: many causes, few therapeutic options. ( Diederich, NJ; McIntyre, DJ, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Diederich, NJ | 1 |
| McIntyre, DJ | 1 |
| Katsunuma, H | 1 |
| Shimizu, T | 1 |
| Ogawa, K | 1 |
| Kubo, H | 1 |
| Ishida, H | 1 |
| Yoshihama, A | 1 |
2 reviews available for zopiclone and Parkinson Disease
| Article | Year |
|---|---|
Sleep disorders in Parkinson's disease: many causes, few therapeutic options.
Topics: Azabicyclo Compounds; Disorders of Excessive Somnolence; Humans; Hypnotics and Sedatives; Parkinson | 2012 |
Treatment of insomnia by concomitant therapy with Zopiclone and Aniracetam in patients with cerebral infarction, cerebroatrophy, Alzheimer's disease and Parkinson's disease.
Topics: Aged; Alzheimer Disease; Atrophy; Azabicyclo Compounds; Cerebral Cortex; Cerebral Infarction; Drug T | 1998 |