zopiclone has been researched along with Methemoglobinemia in 4 studies
zopiclone: S(+)-enantiomer of racemic zopiclone; azabicyclo(4.3.0)nonane; a nonbenzodiazepine; one of the so-called of Z drugs (zopiclone, eszopiclone, zolpidem, and zaleplon) for which there is some correlation with tumors; was term of zopiclone 2004-2007
zopiclone : A pyrrolo[3,4-b]pyrazine compound having a 4-methylpiperazine-1-carboxyl group at the 5-position, a 5-chloropyridin-2-yl group at the 6-position and an oxo-substituent at the 7-position.
Methemoglobinemia: The presence of methemoglobin in the blood, resulting in cyanosis. A small amount of methemoglobin is present in the blood normally, but injury or toxic agents convert a larger proportion of hemoglobin into methemoglobin, which does not function reversibly as an oxygen carrier. Methemoglobinemia may be due to a defect in the enzyme NADH methemoglobin reductase (an autosomal recessive trait) or to an abnormality in hemoglobin M (an autosomal dominant trait). (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To characterize the risk of methemoglobinemia and hemolytic anemia following large overdoses of zopiclone, a cyclopyrrolone hypnotic-sedative and a racemic mixture of R-zopiclone and S-zopiclone (eszopiclone)." | 8.90 | Zopiclone induced methemoglobinemia and hemolytic anemia. ( Chan, TY, 2014) |
| "Methemoglobinemia has not previously been reported following acute zopiclone overdose." | 7.74 | Two cases of methemoglobinemia following zopiclone ingestion. ( Fung, HT; Kam, CW; Lai, CH; Lam, KK; Wong, OF, 2008) |
| "Sulfhemoglobinemia is mainly associated with drugs or intestinal bacterial overgrowth." | 5.72 | [Sulfhemoglobinemia secondary to the use of zopiclone. Report of two cases]. ( Aguirre, H; Benavente, R; Meneses, R; Parada, N; Peña, C; Pineda, C; Sánchez, B; Torres, S, 2022) |
| "To characterize the risk of methemoglobinemia and hemolytic anemia following large overdoses of zopiclone, a cyclopyrrolone hypnotic-sedative and a racemic mixture of R-zopiclone and S-zopiclone (eszopiclone)." | 4.90 | Zopiclone induced methemoglobinemia and hemolytic anemia. ( Chan, TY, 2014) |
| "Methemoglobinemia has not previously been reported following acute zopiclone overdose." | 3.74 | Two cases of methemoglobinemia following zopiclone ingestion. ( Fung, HT; Kam, CW; Lai, CH; Lam, KK; Wong, OF, 2008) |
| "Sulfhemoglobinemia is mainly associated with drugs or intestinal bacterial overgrowth." | 1.72 | [Sulfhemoglobinemia secondary to the use of zopiclone. Report of two cases]. ( Aguirre, H; Benavente, R; Meneses, R; Parada, N; Peña, C; Pineda, C; Sánchez, B; Torres, S, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Benavente, R | 1 |
| Parada, N | 1 |
| Sánchez, B | 1 |
| Meneses, R | 1 |
| Torres, S | 1 |
| Pineda, C | 1 |
| Aguirre, H | 1 |
| Peña, C | 1 |
| Chan, TY | 1 |
| Kung, SW | 1 |
| Tse, ML | 1 |
| Chan, YC | 1 |
| Lau, FL | 1 |
| Tsui, SH | 1 |
| Tam, S | 1 |
| Siu, TS | 1 |
| Fung, HT | 1 |
| Lai, CH | 1 |
| Wong, OF | 1 |
| Lam, KK | 1 |
| Kam, CW | 1 |
1 review available for zopiclone and Methemoglobinemia
| Article | Year |
|---|---|
Zopiclone induced methemoglobinemia and hemolytic anemia.
Topics: Azabicyclo Compounds; Dose-Response Relationship, Drug; Drug Overdose; Erythrocytes; Hemolytic-Uremi | 2014 |
3 other studies available for zopiclone and Methemoglobinemia
| Article | Year |
|---|---|
[Sulfhemoglobinemia secondary to the use of zopiclone. Report of two cases].
Topics: Cyanosis; Female; Humans; Methemoglobinemia; Oximetry; Oxygen; Sulfhemoglobinemia | 2022 |
Zopiclone-associated methemoglobinemia and renal impairment.
Topics: Azabicyclo Compounds; Drug Overdose; Female; Humans; Kidney Diseases; Methemoglobinemia; Middle Aged | 2008 |
Two cases of methemoglobinemia following zopiclone ingestion.
Topics: Adult; Azabicyclo Compounds; Drug Overdose; Enzyme Inhibitors; Female; Humans; Hypnotics and Sedativ | 2008 |