zopiclone has been researched along with Kidney Failure, Chronic in 5 studies
zopiclone: S(+)-enantiomer of racemic zopiclone; azabicyclo(4.3.0)nonane; a nonbenzodiazepine; one of the so-called of Z drugs (zopiclone, eszopiclone, zolpidem, and zaleplon) for which there is some correlation with tumors; was term of zopiclone 2004-2007
zopiclone : A pyrrolo[3,4-b]pyrazine compound having a 4-methylpiperazine-1-carboxyl group at the 5-position, a 5-chloropyridin-2-yl group at the 6-position and an oxo-substituent at the 7-position.
Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Zopiclone is a new hypnotic cyclopyrrolone with a short elimination half-life (5." | 1.28 | Steady state pharmacokinetics of zopiclone during multiple oral dosing (7.5 mg nocte) in patients with severe chronic renal failure. ( De Meyer, M; Frydman, A; Gaillot, J; Le Liboux, A; Maillard, F; Mignon, F; Viron, B, 1990) |
| " Plasma kinetics of ZD are generally well described by a two-compartment open model; in man, terminal half-life is 4-5 h; total body clearance is large (300 ml/mn), renal clearance very low (10 ml/min)." | 1.27 | Pharmacokinetics and metabolism of zopiclone. ( Dreyfus, JF; Gaillot, J; Heusse, D; Hougton, GW; Marc Aurele, J, 1983) |
| "Maximal blood concentration (Cmax), time to concentration peak (Tmax), area under the serum concentration-time curve (AUC infinity) and half-life (t1/2) after the oral administration of zopiclone 7." | 1.27 | Comparison of zopiclone pharmacokinetics in patients with impaired renal function and normal subjects. Effect of hemodialysis. ( Bourgoin, J; Caille, G; Marc-Aurele, J, 1987) |
| " Plasma kinetics of ZD are generally well described by a two-compartment open model; in man, terminal half-life is 4-5 h; total body clearance is large (300 ml/mn), renal clearance very low (10 ml/min)." | 1.26 | Pharmacokinetics and metabolism of zopiclone. ( Dreyfus, JF; Gaillot, J; Heusse, D; Hougton, GW; Marc Aurele, J, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (80.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gaillot, J | 4 |
| Heusse, D | 2 |
| Hougton, GW | 2 |
| Marc Aurele, J | 2 |
| Dreyfus, JF | 2 |
| Viron, B | 1 |
| De Meyer, M | 1 |
| Le Liboux, A | 2 |
| Frydman, A | 2 |
| Maillard, F | 1 |
| Mignon, F | 1 |
| Marc-Aurele, J | 1 |
| Caille, G | 1 |
| Bourgoin, J | 1 |
5 other studies available for zopiclone and Kidney Failure, Chronic
| Article | Year |
|---|---|
Pharmacokinetics and metabolism of zopiclone.
Topics: Administration, Oral; Aged; Aging; Animals; Autoradiography; Azabicyclo Compounds; Biotransformation | 1983 |
Pharmacokinetics and metabolism of zopiclone.
Topics: Administration, Oral; Adult; Aged; Aging; Animals; Autoradiography; Azabicyclo Compounds; Dogs; Fema | 1982 |
Steady state pharmacokinetics of zopiclone during multiple oral dosing (7.5 mg nocte) in patients with severe chronic renal failure.
Topics: Administration, Oral; Adolescent; Adult; Aged; Azabicyclo Compounds; Dose-Response Relationship, Dru | 1990 |
Comparison of zopiclone pharmacokinetics in patients with impaired renal function and normal subjects. Effect of hemodialysis.
Topics: Adult; Azabicyclo Compounds; Female; Half-Life; Humans; Hypnotics and Sedatives; Kidney Failure, Chr | 1987 |
Simultaneous determination of zopiclone and its two major metabolites (N-oxide and N-desmethyl) in human biological fluids by reversed-phase high-performance liquid chromatography.
Topics: Adolescent; Adult; Aged; Azabicyclo Compounds; Chromatography, High Pressure Liquid; Humans; Hypnoti | 1987 |