zopiclone has been researched along with Drug Overdose in 17 studies
zopiclone: S(+)-enantiomer of racemic zopiclone; azabicyclo(4.3.0)nonane; a nonbenzodiazepine; one of the so-called of Z drugs (zopiclone, eszopiclone, zolpidem, and zaleplon) for which there is some correlation with tumors; was term of zopiclone 2004-2007
zopiclone : A pyrrolo[3,4-b]pyrazine compound having a 4-methylpiperazine-1-carboxyl group at the 5-position, a 5-chloropyridin-2-yl group at the 6-position and an oxo-substituent at the 7-position.
Drug Overdose: Accidental or deliberate use of a medication or street drug in excess of normal dosage.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To characterize the risk of methemoglobinemia and hemolytic anemia following large overdoses of zopiclone, a cyclopyrrolone hypnotic-sedative and a racemic mixture of R-zopiclone and S-zopiclone (eszopiclone)." | 8.90 | Zopiclone induced methemoglobinemia and hemolytic anemia. ( Chan, TY, 2014) |
| "Methemoglobinemia has not previously been reported following acute zopiclone overdose." | 7.74 | Two cases of methemoglobinemia following zopiclone ingestion. ( Fung, HT; Kam, CW; Lai, CH; Lam, KK; Wong, OF, 2008) |
| "To characterize the risk of methemoglobinemia and hemolytic anemia following large overdoses of zopiclone, a cyclopyrrolone hypnotic-sedative and a racemic mixture of R-zopiclone and S-zopiclone (eszopiclone)." | 4.90 | Zopiclone induced methemoglobinemia and hemolytic anemia. ( Chan, TY, 2014) |
| " A 52-year-old man with a history of depression treated with escitalopram 10 mg/day, extended-release morphine 30 mg/day and zopiclone 15 mg/day was found unconscious at his home." | 3.74 | Corrected QT interval prolongation after an overdose of escitalopram, morphine, oxycodone, zopiclone and benzodiazepines. ( Baranchuk, A; Gibson, K; Methot, M; Simpson, CS; Strum, D, 2008) |
| "Methemoglobinemia has not previously been reported following acute zopiclone overdose." | 3.74 | Two cases of methemoglobinemia following zopiclone ingestion. ( Fung, HT; Kam, CW; Lai, CH; Lam, KK; Wong, OF, 2008) |
| "Flumazenil has been reported to reverse sedation from all three Z-drugs." | 2.49 | The clinical and forensic toxicology of Z-drugs. ( Gunja, N, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 9 (52.94) | 29.6817 |
| 2010's | 7 (41.18) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Szmulewicz, A | 1 |
| Bateman, BT | 1 |
| Levin, R | 1 |
| Huybrechts, KF | 1 |
| Cimolai, N | 1 |
| Isoardi, KZ | 1 |
| Harris, K | 1 |
| Carmichael, KE | 1 |
| Dimeski, G | 1 |
| Chan, BSH | 1 |
| Page, CB | 1 |
| Gunja, N | 1 |
| Chan, TY | 1 |
| Zhang, YZ | 1 |
| He, HY | 1 |
| She, CM | 1 |
| Lian, J | 1 |
| Baranchuk, A | 1 |
| Simpson, CS | 1 |
| Methot, M | 1 |
| Gibson, K | 1 |
| Strum, D | 1 |
| Yang, CC | 1 |
| Deng, JF | 1 |
| Kung, SW | 1 |
| Tse, ML | 1 |
| Chan, YC | 1 |
| Lau, FL | 1 |
| Tsui, SH | 1 |
| Tam, S | 1 |
| Siu, TS | 1 |
| Fung, HT | 2 |
| Lai, CH | 2 |
| Wong, OF | 2 |
| Lam, SK | 1 |
| Lam, KK | 2 |
| Hillyard, SG | 1 |
| Barrera-Groba, C | 1 |
| Tighe, R | 1 |
| Neckelmann, D | 1 |
| Maehlum, E | 1 |
| Waage, IM | 1 |
| Kuntze, MF | 1 |
| Bullinger, AH | 1 |
| Mueller-Spahn, F | 1 |
| Lovett, B | 1 |
| Watts, D | 1 |
| Grossman, M | 1 |
| Kam, CW | 1 |
| Bates, D | 1 |
| Mintz, M | 1 |
| Bramness, JG | 1 |
| Arnestad, M | 1 |
| Karinen, R | 1 |
| Hilberg, T | 1 |
4 reviews available for zopiclone and Drug Overdose
| Article | Year |
|---|---|
The clinical and forensic toxicology of Z-drugs.
Topics: Acetamides; Azabicyclo Compounds; Coma; Drug Overdose; Flumazenil; GABA Modulators; GABA-A Receptor | 2013 |
Zopiclone induced methemoglobinemia and hemolytic anemia.
Topics: Azabicyclo Compounds; Dose-Response Relationship, Drug; Drug Overdose; Erythrocytes; Hemolytic-Uremi | 2014 |
[Research Progress on Forensic Toxicology of Z-drugs].
Topics: Acetamides; Azabicyclo Compounds; Drug Overdose; Forensic Medicine; Forensic Toxicology; Humans; Hyp | 2015 |
Phytonadione therapy in a multiple-drug overdose involving warfarin.
Topics: Acetaminophen; Acetylcysteine; Aged; Analgesics, Non-Narcotic; Anti-Bacterial Agents; Anticoagulants | 2000 |
13 other studies available for zopiclone and Drug Overdose
| Article | Year |
|---|---|
The Risk of Overdose With Concomitant Use of Z-Drugs and Prescription Opioids: A Population-Based Cohort Study.
Topics: Acetamides; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Azabicyclo Compounds; Dr | 2021 |
Zopiclone overdose and flumazenil rescue.
Topics: Azabicyclo Compounds; Benzodiazepines; Drug Overdose; Flumazenil; Humans; Piperazines | 2017 |
Acute bone marrow suppression and gastrointestinal toxicity following acute oral methotrexate overdose.
Topics: Anti-Bacterial Agents; Antirheumatic Agents; Azabicyclo Compounds; Blood Transfusion; Bone Marrow Di | 2018 |
Corrected QT interval prolongation after an overdose of escitalopram, morphine, oxycodone, zopiclone and benzodiazepines.
Topics: Antidepressive Agents, Second-Generation; Arrhythmias, Cardiac; Azabicyclo Compounds; Benzodiazepine | 2008 |
Utility of flumazenil in zopiclone overdose.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antidotes; Azabicyclo Compounds; Drug Overdose; Female; | 2008 |
Zopiclone-associated methemoglobinemia and renal impairment.
Topics: Azabicyclo Compounds; Drug Overdose; Female; Humans; Kidney Diseases; Methemoglobinemia; Middle Aged | 2008 |
Hemolytic anemia after zopiclone overdose.
Topics: Anemia, Hemolytic; Azabicyclo Compounds; Drug Overdose; Female; Follow-Up Studies; Humans; Hypnotics | 2009 |
Intralipid reverses coma associated with zopiclone and venlafaxine overdose.
Topics: Antidepressive Agents, Second-Generation; Azabicyclo Compounds; Coma; Cyclohexanols; Drug Overdose; | 2010 |
Sertindole and fluoxetine overdose with benign outcome.
Topics: Adult; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Azabicyclo Compounds; Blood P | 2010 |
Excessive use of zopiclone: a case report.
Topics: Aged; Azabicyclo Compounds; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Ove | 2002 |
Prolonged coma after eszopiclone overdose.
Topics: Aged, 80 and over; Azabicyclo Compounds; Coma; Drug Overdose; Female; Humans; Hypnotics and Sedative | 2007 |
Two cases of methemoglobinemia following zopiclone ingestion.
Topics: Adult; Azabicyclo Compounds; Drug Overdose; Enzyme Inhibitors; Female; Humans; Hypnotics and Sedativ | 2008 |
Fatal overdose of zopiclone in an elderly woman with bronchogenic carcinoma.
Topics: Aged; Autopsy; Azabicyclo Compounds; Cause of Death; Chromatography, High Pressure Liquid; Drug Over | 2001 |