zopiclone has been researched along with Depressive Disorder in 7 studies
zopiclone: S(+)-enantiomer of racemic zopiclone; azabicyclo(4.3.0)nonane; a nonbenzodiazepine; one of the so-called of Z drugs (zopiclone, eszopiclone, zolpidem, and zaleplon) for which there is some correlation with tumors; was term of zopiclone 2004-2007
zopiclone : A pyrrolo[3,4-b]pyrazine compound having a 4-methylpiperazine-1-carboxyl group at the 5-position, a 5-chloropyridin-2-yl group at the 6-position and an oxo-substituent at the 7-position.
Depressive Disorder: An affective disorder manifested by either a dysphoric mood or loss of interest or pleasure in usual activities. The mood disturbance is prominent and relatively persistent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Zopiclone use was assessed to provide an indirect evaluation of the possible hypnotic activity of both treatments." | 2.70 | Efficacy and safety of tianeptine in major depression: evidence from a 3-month controlled clinical trial versus paroxetine. ( Azoulay, P; Septien, L; Waintraub, L, 2002) |
| "Nefazodone is a relatively potent inhibitor of CYP3A4, a hepatic isoenzyme thought to play a major role in the metabolic elimination of zopiclone." | 1.31 | Possible interaction of zopiclone and nefazodone. ( Alderman, CP; Condon, JT; Gebauer, MG; Gilbert, AL, 2001) |
| "Furthermore, the patient suffered from convulsion on two occasions following abrupt withdrawal of zopiclone." | 1.28 | Misuse of zopiclone and convulsions during withdrawal. ( Aranko, K; Henriksson, M; Hublin, C; Seppäläinen, AM, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Osler, M | 1 |
| Jørgensen, MB | 1 |
| Yen, CF | 1 |
| Yen, CN | 1 |
| Ko, CH | 1 |
| Hwang, TJ | 1 |
| Chen, CS | 1 |
| Chen, TT | 1 |
| Su, PW | 1 |
| Chen, ST | 1 |
| Lin, JJ | 1 |
| Isacsson, G | 1 |
| Holmgren, A | 1 |
| Osby, U | 1 |
| Ahlner, J | 1 |
| Fava, M | 1 |
| McCall, WV | 1 |
| Krystal, A | 1 |
| Wessel, T | 1 |
| Rubens, R | 1 |
| Caron, J | 1 |
| Amato, D | 1 |
| Roth, T | 1 |
| Alderman, CP | 1 |
| Gebauer, MG | 1 |
| Gilbert, AL | 1 |
| Condon, JT | 1 |
| Waintraub, L | 1 |
| Septien, L | 1 |
| Azoulay, P | 1 |
| Aranko, K | 1 |
| Henriksson, M | 1 |
| Hublin, C | 1 |
| Seppäläinen, AM | 1 |
2 trials available for zopiclone and Depressive Disorder
| Article | Year |
|---|---|
Eszopiclone co-administered with fluoxetine in patients with insomnia coexisting with major depressive disorder.
Topics: Adult; Antidepressive Agents, Second-Generation; Azabicyclo Compounds; Depressive Disorder; Double-B | 2006 |
Efficacy and safety of tianeptine in major depression: evidence from a 3-month controlled clinical trial versus paroxetine.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Antidepressive Age | 2002 |
5 other studies available for zopiclone and Depressive Disorder
| Article | Year |
|---|---|
Associations of Benzodiazepines, Z-Drugs, and Other Anxiolytics With Subsequent Dementia in Patients With Affective Disorders: A Nationwide Cohort and Nested Case-Control Study.
Topics: Aged; Aged, 80 and over; Anti-Anxiety Agents; Antidepressive Agents; Antipsychotic Agents; Azabicycl | 2020 |
Correlates of dependence and beliefs about the use of hypnotics among zolpidem and zopiclone users.
Topics: Adult; Azabicyclo Compounds; Depressive Disorder; Diagnosis, Dual (Psychiatry); Female; Hospitals; H | 2015 |
Decrease in suicide among the individuals treated with antidepressants: a controlled study of antidepressants in suicide, Sweden 1995-2005.
Topics: Analgesics, Opioid; Antidepressive Agents; Azabicyclo Compounds; Case-Control Studies; Cause of Deat | 2009 |
Possible interaction of zopiclone and nefazodone.
Topics: Aged; Aged, 80 and over; Antidepressive Agents, Second-Generation; Azabicyclo Compounds; Depressive | 2001 |
Misuse of zopiclone and convulsions during withdrawal.
Topics: Adult; Azabicyclo Compounds; Depressive Disorder; Humans; Hypnotics and Sedatives; Male; Piperazines | 1991 |