Page last updated: 2024-11-06

zopiclone and Depressive Disorder, Major

zopiclone has been researched along with Depressive Disorder, Major in 4 studies

zopiclone: S(+)-enantiomer of racemic zopiclone; azabicyclo(4.3.0)nonane; a nonbenzodiazepine; one of the so-called of Z drugs (zopiclone, eszopiclone, zolpidem, and zaleplon) for which there is some correlation with tumors; was term of zopiclone 2004-2007
zopiclone : A pyrrolo[3,4-b]pyrazine compound having a 4-methylpiperazine-1-carboxyl group at the 5-position, a 5-chloropyridin-2-yl group at the 6-position and an oxo-substituent at the 7-position.

Depressive Disorder, Major: Disorder in which five (or more) of the following symptoms have been present during the same 2-week period and represent a change from previous functioning; at least one of the symptoms is either (1) depressed mood or (2) loss of interest or pleasure. Symptoms include: depressed mood most of the day, nearly every daily; markedly diminished interest or pleasure in activities most of the day, nearly every day; significant weight loss when not dieting or weight gain; Insomnia or hypersomnia nearly every day; psychomotor agitation or retardation nearly every day; fatigue or loss of energy nearly every day; feelings of worthlessness or excessive or inappropriate guilt; diminished ability to think or concentrate, or indecisiveness, nearly every day; or recurrent thoughts of death, recurrent suicidal ideation without a specific plan, or a suicide attempt. (DSM-5)

Research Excerpts

ExcerptRelevanceReference
"Insomnia and major depressive disorder (MDD) may coexist."2.73Evaluation of eszopiclone discontinuation after cotherapy with fluoxetine for insomnia with coexisting depression. ( Caron, J; Fava, M; Krystal, A; McCall, WV; Roth, T; Rubens, R; Wessel, T; Wilson, P, 2007)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's1 (25.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Osler, M1
Jørgensen, MB1
Abba-Aji, A1
Bardoloi, P1
Sicot, R1
Krystal, A1
Fava, M1
Rubens, R1
Wessel, T1
Caron, J1
Wilson, P1
Roth, T1
McCall, WV1

Trials

1 trial available for zopiclone and Depressive Disorder, Major

ArticleYear
Evaluation of eszopiclone discontinuation after cotherapy with fluoxetine for insomnia with coexisting depression.
    Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2007, Feb-15, Volume: 3, Issue:1

    Topics: Adult; Azabicyclo Compounds; Comorbidity; Depressive Disorder, Major; Double-Blind Method; Drug Admi

2007

Other Studies

3 other studies available for zopiclone and Depressive Disorder, Major

ArticleYear
Associations of Benzodiazepines, Z-Drugs, and Other Anxiolytics With Subsequent Dementia in Patients With Affective Disorders: A Nationwide Cohort and Nested Case-Control Study.
    The American journal of psychiatry, 2020, 06-01, Volume: 177, Issue:6

    Topics: Aged; Aged, 80 and over; Anti-Anxiety Agents; Antidepressive Agents; Antipsychotic Agents; Azabicycl

2020
Paradoxical insomnia in a patient taking zopiclone.
    BMJ case reports, 2017, Jan-19, Volume: 2017

    Topics: Antidepressive Agents; Azabicyclo Compounds; Citalopram; Deprescriptions; Depressive Disorder, Major

2017
[Love, humor and psychosis in an atypical depression].
    L'Encephale, 2005, Volume: 31 Pt 2

    Topics: Antidepressive Agents; Antipsychotic Agents; Azabicyclo Compounds; Benzodiazepines; Clonazepam; Cycl

2005