zopiclone has been researched along with Chronic Kidney Failure in 5 studies
zopiclone: S(+)-enantiomer of racemic zopiclone; azabicyclo(4.3.0)nonane; a nonbenzodiazepine; one of the so-called of Z drugs (zopiclone, eszopiclone, zolpidem, and zaleplon) for which there is some correlation with tumors; was term of zopiclone 2004-2007
zopiclone : A pyrrolo[3,4-b]pyrazine compound having a 4-methylpiperazine-1-carboxyl group at the 5-position, a 5-chloropyridin-2-yl group at the 6-position and an oxo-substituent at the 7-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Zopiclone is a new hypnotic cyclopyrrolone with a short elimination half-life (5." | 1.28 | Steady state pharmacokinetics of zopiclone during multiple oral dosing (7.5 mg nocte) in patients with severe chronic renal failure. ( De Meyer, M; Frydman, A; Gaillot, J; Le Liboux, A; Maillard, F; Mignon, F; Viron, B, 1990) |
| " Plasma kinetics of ZD are generally well described by a two-compartment open model; in man, terminal half-life is 4-5 h; total body clearance is large (300 ml/mn), renal clearance very low (10 ml/min)." | 1.27 | Pharmacokinetics and metabolism of zopiclone. ( Dreyfus, JF; Gaillot, J; Heusse, D; Hougton, GW; Marc Aurele, J, 1983) |
| "Maximal blood concentration (Cmax), time to concentration peak (Tmax), area under the serum concentration-time curve (AUC infinity) and half-life (t1/2) after the oral administration of zopiclone 7." | 1.27 | Comparison of zopiclone pharmacokinetics in patients with impaired renal function and normal subjects. Effect of hemodialysis. ( Bourgoin, J; Caille, G; Marc-Aurele, J, 1987) |
| " Plasma kinetics of ZD are generally well described by a two-compartment open model; in man, terminal half-life is 4-5 h; total body clearance is large (300 ml/mn), renal clearance very low (10 ml/min)." | 1.26 | Pharmacokinetics and metabolism of zopiclone. ( Dreyfus, JF; Gaillot, J; Heusse, D; Hougton, GW; Marc Aurele, J, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (80.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gaillot, J | 4 |
| Heusse, D | 2 |
| Hougton, GW | 2 |
| Marc Aurele, J | 2 |
| Dreyfus, JF | 2 |
| Viron, B | 1 |
| De Meyer, M | 1 |
| Le Liboux, A | 2 |
| Frydman, A | 2 |
| Maillard, F | 1 |
| Mignon, F | 1 |
| Marc-Aurele, J | 1 |
| Caille, G | 1 |
| Bourgoin, J | 1 |
5 other studies available for zopiclone and Chronic Kidney Failure
| Article | Year |
|---|---|
Pharmacokinetics and metabolism of zopiclone.
Topics: Administration, Oral; Aged; Aging; Animals; Autoradiography; Azabicyclo Compounds; Biotransformation | 1983 |
Pharmacokinetics and metabolism of zopiclone.
Topics: Administration, Oral; Adult; Aged; Aging; Animals; Autoradiography; Azabicyclo Compounds; Dogs; Fema | 1982 |
Steady state pharmacokinetics of zopiclone during multiple oral dosing (7.5 mg nocte) in patients with severe chronic renal failure.
Topics: Administration, Oral; Adolescent; Adult; Aged; Azabicyclo Compounds; Dose-Response Relationship, Dru | 1990 |
Comparison of zopiclone pharmacokinetics in patients with impaired renal function and normal subjects. Effect of hemodialysis.
Topics: Adult; Azabicyclo Compounds; Female; Half-Life; Humans; Hypnotics and Sedatives; Kidney Failure, Chr | 1987 |
Simultaneous determination of zopiclone and its two major metabolites (N-oxide and N-desmethyl) in human biological fluids by reversed-phase high-performance liquid chromatography.
Topics: Adolescent; Adult; Aged; Azabicyclo Compounds; Chromatography, High Pressure Liquid; Humans; Hypnoti | 1987 |