zopiclone has been researched along with Alzheimer Disease in 2 studies
zopiclone: S(+)-enantiomer of racemic zopiclone; azabicyclo(4.3.0)nonane; a nonbenzodiazepine; one of the so-called of Z drugs (zopiclone, eszopiclone, zolpidem, and zaleplon) for which there is some correlation with tumors; was term of zopiclone 2004-2007
zopiclone : A pyrrolo[3,4-b]pyrazine compound having a 4-methylpiperazine-1-carboxyl group at the 5-position, a 5-chloropyridin-2-yl group at the 6-position and an oxo-substituent at the 7-position.
Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Louzada, LL | 1 |
| Machado, FV | 1 |
| Quintas, JL | 1 |
| Ribeiro, GA | 1 |
| Silva, MV | 1 |
| Mendonça-Silva, DL | 1 |
| Gonçalves, BSB | 1 |
| Nóbrega, OT | 1 |
| Camargos, EF | 1 |
| Katsunuma, H | 1 |
| Shimizu, T | 1 |
| Ogawa, K | 1 |
| Kubo, H | 1 |
| Ishida, H | 1 |
| Yoshihama, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Z-Drugs for the Treatment of Sleep Disorders in Alzheimer's Disease: a Randomized, Triple-blind, Placebo-controlled Study[NCT03075241] | Phase 3 | 62 participants (Actual) | Interventional | 2016-10-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for zopiclone and Alzheimer Disease
| Article | Year |
|---|---|
Treatment of insomnia by concomitant therapy with Zopiclone and Aniracetam in patients with cerebral infarction, cerebroatrophy, Alzheimer's disease and Parkinson's disease.
Topics: Aged; Alzheimer Disease; Atrophy; Azabicyclo Compounds; Cerebral Cortex; Cerebral Infarction; Drug T | 1998 |
1 trial available for zopiclone and Alzheimer Disease
| Article | Year |
|---|---|
The efficacy and safety of zolpidem and zopiclone to treat insomnia in Alzheimer's disease: a randomized, triple-blind, placebo-controlled trial.
Topics: Aged, 80 and over; Alzheimer Disease; Azabicyclo Compounds; Double-Blind Method; Humans; Hypnotics a | 2022 |