zonisamide has been researched along with Status Epilepticus in 6 studies
Zonisamide: A benzisoxazole and sulfonamide derivative that acts as a CALCIUM CHANNEL blocker. It is used primarily as an adjunctive antiepileptic agent for the treatment of PARTIAL SEIZURES, with or without secondary generalization.
zonisamide : A 1,2-benzoxazole compound having a sulfamoylmethyl substituent at the 3-position.
Status Epilepticus: A prolonged seizure or seizures repeated frequently enough to prevent recovery between episodes occurring over a period of 20-30 minutes. The most common subtype is generalized tonic-clonic status epilepticus, a potentially fatal condition associated with neuronal injury and respiratory and metabolic dysfunction. Nonconvulsive forms include petit mal status and complex partial status, which may manifest as behavioral disturbances. Simple partial status epilepticus consists of persistent motor, sensory, or autonomic seizures that do not impair cognition (see also EPILEPSIA PARTIALIS CONTINUA). Subclinical status epilepticus generally refers to seizures occurring in an unresponsive or comatose individual in the absence of overt signs of seizure activity. (From N Engl J Med 1998 Apr 2;338(14):970-6; Neurologia 1997 Dec;12 Suppl 6:25-30)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We present a summary of clinical cases of oral zonisamide (ZNS) used to treat refractory and super-refractory episodes of status epilepticus (SE)." | 9.05 | Treatment of status epilepticus with zonisamide: A multicenter cohort study of 34 patients and review of literature. ( Bauer, S; Hubert, K; Knake, S; Rosenow, F; Strzelczyk, A; Voss, M, 2020) |
| " Limbic seizure status epilepticus was induced by a unilateral microinjection of kainic acid (KA) into the amygdala." | 7.69 | Zonisamide: electrophysiological and metabolic changes in kainic acid-induced limbic seizures in rats. ( Fujita, T; Nakai, H; Takano, K; Tanaka, T; Yonemasu, Y, 1995) |
| "We present a summary of clinical cases of oral zonisamide (ZNS) used to treat refractory and super-refractory episodes of status epilepticus (SE)." | 5.05 | Treatment of status epilepticus with zonisamide: A multicenter cohort study of 34 patients and review of literature. ( Bauer, S; Hubert, K; Knake, S; Rosenow, F; Strzelczyk, A; Voss, M, 2020) |
| "Based on these data, lacosamide and eslicarbazepine might be more favorable in the treatment of refractory status epilepticus in poststroke epilepsy, when administered as second- or third-line ASMs before anesthesia." | 4.31 | Third-Generation Antiseizure Medication in the Treatment of Benzodiazepine-Refractory Status Epilepticus in Poststroke Epilepsy: A Retrospective Observational Register-Based Study. ( Gonzalez-Escamilla, G; Groppa, S; Sandner, K; Stuckrad-Barre, SV; Vieth, T; Winter, Y, 2023) |
| "This is a case study in managing refractory status epilepticus under long-term usage of secobarbital (SB)." | 3.70 | [Experience in managing refractory status epilepticus caused by viral encephalitis under long-term anesthesia with barbiturate: a case report]. ( Fujioka, Y; Ohori, N; Ohta, M, 1998) |
| " Limbic seizure status epilepticus was induced by a unilateral microinjection of kainic acid (KA) into the amygdala." | 3.69 | Zonisamide: electrophysiological and metabolic changes in kainic acid-induced limbic seizures in rats. ( Fujita, T; Nakai, H; Takano, K; Tanaka, T; Yonemasu, Y, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Winter, Y | 1 |
| Sandner, K | 1 |
| Vieth, T | 1 |
| Gonzalez-Escamilla, G | 1 |
| Stuckrad-Barre, SV | 1 |
| Groppa, S | 1 |
| Hubert, K | 1 |
| Knake, S | 1 |
| Bauer, S | 1 |
| Voss, M | 1 |
| Rosenow, F | 1 |
| Strzelczyk, A | 1 |
| Takano, K | 2 |
| Tanaka, T | 2 |
| Fujita, T | 2 |
| Nakai, H | 1 |
| Yonemasu, Y | 2 |
| Ohori, N | 1 |
| Fujioka, Y | 1 |
| Ohta, M | 1 |
| Yoshimura, I | 1 |
| Kaneko, S | 1 |
| Yoshimura, N | 1 |
| Murakami, T | 1 |
| Tanaka, S | 1 |
1 review available for zonisamide and Status Epilepticus
| Article | Year |
|---|---|
Treatment of status epilepticus with zonisamide: A multicenter cohort study of 34 patients and review of literature.
Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Ataxia; Cohort Studies; Drug Resistant Epilepsy; Fe | 2020 |
5 other studies available for zonisamide and Status Epilepticus
| Article | Year |
|---|---|
Third-Generation Antiseizure Medication in the Treatment of Benzodiazepine-Refractory Status Epilepticus in Poststroke Epilepsy: A Retrospective Observational Register-Based Study.
Topics: Aged; Anticonvulsants; Benzodiazepines; Epilepsy; Humans; Ischemic Stroke; Lacosamide; Middle Aged; | 2023 |
Zonisamide: electrophysiological and metabolic changes in kainic acid-induced limbic seizures in rats.
Topics: Animals; Anticonvulsants; Autoradiography; Brain; Electroencephalography; Glucose; Isoxazoles; Kaini | 1995 |
[Experience in managing refractory status epilepticus caused by viral encephalitis under long-term anesthesia with barbiturate: a case report].
Topics: Adjuvants, Anesthesia; Adult; Anesthesia; Anticonvulsants; Encephalitis, Viral; Female; Herpes Simpl | 1998 |
Long-term observations of two siblings with Lafora disease treated with zonisamide.
Topics: Adult; Anticonvulsants; Fatal Outcome; Female; Follow-Up Studies; Humans; Isoxazoles; Lafora Disease | 2001 |
[Effect of anticonvulsants upon experimental limbic seizure status and regional cerebral blood flow in the hippocampus].
Topics: Animals; Anticonvulsants; Cats; Diazepam; Electroencephalography; Hippocampus; Isoxazoles; Phenobarb | 1992 |