zonisamide has been researched along with Sleep Wake Disorders in 4 studies
Zonisamide: A benzisoxazole and sulfonamide derivative that acts as a CALCIUM CHANNEL blocker. It is used primarily as an adjunctive antiepileptic agent for the treatment of PARTIAL SEIZURES, with or without secondary generalization.
zonisamide : A 1,2-benzoxazole compound having a sulfamoylmethyl substituent at the 3-position.
Sleep Wake Disorders: Abnormal sleep-wake schedule or pattern associated with the CIRCADIAN RHYTHM which affect the length, timing, and/or rigidity of the sleep-wake cycle relative to the day-night cycle.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We aimed to evaluate the effect of zonisamide (ZNS) on motor symptoms and nonmotor symptoms such as depressive symptoms and sleep problems in Parkinson's disease (PD) patients with or without tremor." | 5.41 | Zonisamide effects on sleep problems and depressive symptoms in Parkinson's disease. ( Fujita, H; Funakoshi, K; Haruyama, Y; Hirata, K; Kadowaki, T; Matsubara, T; Suzuki, K; Watanabe, Y, 2021) |
| " The most common adverse events were somnolence, headache, dizziness, and nausea during the titration phase and headache and pharyngitis during the fixed-dose assessment phase." | 2.71 | Dose-dependent safety and efficacy of zonisamide: a randomized, double-blind, placebo-controlled study in patients with refractory partial seizures. ( Bitenskyy, V; Brodie, MJ; Duncan, R; Lucas, C; Solyom, A; Vespignani, H, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Miyaue, N | 1 |
| Yabe, H | 1 |
| Suzuki, K | 1 |
| Fujita, H | 1 |
| Matsubara, T | 1 |
| Haruyama, Y | 1 |
| Kadowaki, T | 1 |
| Funakoshi, K | 1 |
| Watanabe, Y | 1 |
| Hirata, K | 1 |
| Brodie, MJ | 1 |
| Duncan, R | 1 |
| Vespignani, H | 1 |
| Solyom, A | 1 |
| Bitenskyy, V | 1 |
| Lucas, C | 1 |
| Ozawa, H | 1 |
| Sasaki, M | 1 |
| Sugai, K | 1 |
| Yano, H | 1 |
3 trials available for zonisamide and Sleep Wake Disorders
| Article | Year |
|---|---|
Polysomnographic and Clinical Parameters before and after Zonisamide Therapy for Parkinson's Disease.
Topics: Humans; Parkinson Disease; Polysomnography; Quality of Life; Sleep; Sleep Wake Disorders; Zonisamide | 2023 |
Zonisamide effects on sleep problems and depressive symptoms in Parkinson's disease.
Topics: Depression; Humans; Parkinson Disease; Sleep Wake Disorders; Tremor; Zonisamide | 2021 |
Dose-dependent safety and efficacy of zonisamide: a randomized, double-blind, placebo-controlled study in patients with refractory partial seizures.
Topics: Adolescent; Adult; Age Factors; Aged; Anticonvulsants; Child; Dose-Response Relationship, Drug; Doub | 2005 |
1 other study available for zonisamide and Sleep Wake Disorders
| Article | Year |
|---|---|
[A case of behavior disorder with gait and sleep disturbances induced by zonisamide].
Topics: Anticonvulsants; Child; Female; Gait; Humans; Isoxazoles; Mental Disorders; Sleep Wake Disorders; Zo | 1995 |