zonisamide has been researched along with Sleep Apnea, Obstructive in 2 studies
Zonisamide: A benzisoxazole and sulfonamide derivative that acts as a CALCIUM CHANNEL blocker. It is used primarily as an adjunctive antiepileptic agent for the treatment of PARTIAL SEIZURES, with or without secondary generalization.
zonisamide : A 1,2-benzoxazole compound having a sulfamoylmethyl substituent at the 3-position.
Sleep Apnea, Obstructive: A disorder characterized by recurrent apneas during sleep despite persistent respiratory efforts. It is due to upper airway obstruction. The respiratory pauses may induce HYPERCAPNIA or HYPOXIA. Cardiac arrhythmias and elevation of systemic and pulmonary arterial pressures may occur. Frequent partial arousals occur throughout sleep, resulting in relative SLEEP DEPRIVATION and daytime tiredness. Associated conditions include OBESITY; ACROMEGALY; MYXEDEMA; micrognathia; MYOTONIC DYSTROPHY; adenotonsilar dystrophy; and NEUROMUSCULAR DISEASES. (From Adams et al., Principles of Neurology, 6th ed, p395)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Zonisamide inhibits carbonic anhydrase, and induces weight loss in obese patients." | 5.19 | Zonisamide reduces obstructive sleep apnoea: a randomised placebo-controlled study. ( Eskandari, D; Grote, L; Hedner, J; Karimi, M; Stenlöf, K; Zou, D, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Eskandari, D | 1 |
| Zou, D | 1 |
| Karimi, M | 1 |
| Stenlöf, K | 1 |
| Grote, L | 1 |
| Hedner, J | 1 |
| Aylwin, S | 1 |
| Al-Zaman, Y | 1 |
1 review available for zonisamide and Sleep Apnea, Obstructive
| Article | Year |
|---|---|
Emerging concepts in the medical and surgical treatment of obesity.
Topics: Adipose Tissue; Amyloid; Anticonvulsants; Antidepressive Agents; Anxiety; Appetite Regulation; Baria | 2008 |
1 trial available for zonisamide and Sleep Apnea, Obstructive
| Article | Year |
|---|---|
Zonisamide reduces obstructive sleep apnoea: a randomised placebo-controlled study.
Topics: Aged; Anthropometry; Body Mass Index; Body Weight; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase | 2014 |