Page last updated: 2024-11-05

zonisamide and Peripheral Nervous System Diseases

zonisamide has been researched along with Peripheral Nervous System Diseases in 2 studies

Zonisamide: A benzisoxazole and sulfonamide derivative that acts as a CALCIUM CHANNEL blocker. It is used primarily as an adjunctive antiepileptic agent for the treatment of PARTIAL SEIZURES, with or without secondary generalization.
zonisamide : A 1,2-benzoxazole compound having a sulfamoylmethyl substituent at the 3-position.

Peripheral Nervous System Diseases: Diseases of the peripheral nerves external to the brain and spinal cord, which includes diseases of the nerve roots, ganglia, plexi, autonomic nerves, sensory nerves, and motor nerves.

Research Excerpts

ExcerptRelevanceReference
" Based on the experience with carbamazepine, gabapentin, and lamotrigine, these newer AEDs are being investigated for the management of neuropathic pain."8.82Oxcarbazepine, topiramate, zonisamide, and levetiracetam: potential use in neuropathic pain. ( Guay, DR, 2003)
" Based on the experience with carbamazepine, gabapentin, and lamotrigine, these newer AEDs are being investigated for the management of neuropathic pain."4.82Oxcarbazepine, topiramate, zonisamide, and levetiracetam: potential use in neuropathic pain. ( Guay, DR, 2003)
"Pretreatment with zonisamide (100 μM) alleviated the DRG neuronal death caused by OHP (75 μM) and the protective effects were attenuated by a co-incubation with 25 μM of the mitogen-activated protein kinase (MAPK; MEK/ERK) inhibitor, U0126, or the phosphatidyl inositol-3'-phosphate-kinase (PI3K) inhibitor, LY294002."1.72Pretreatment with Zonisamide Mitigates Oxaliplatin-Induced Toxicity in Rat DRG Neurons and DRG Neuron-Schwann Cell Co-Cultures. ( Sango, K; Takaku, S, 2022)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Takaku, S1
Sango, K1
Guay, DR1

Reviews

1 review available for zonisamide and Peripheral Nervous System Diseases

ArticleYear
Oxcarbazepine, topiramate, zonisamide, and levetiracetam: potential use in neuropathic pain.
    The American journal of geriatric pharmacotherapy, 2003, Volume: 1, Issue:1

    Topics: Aged; Analgesics, Non-Narcotic; Animals; Carbamazepine; Clinical Trials as Topic; Dose-Response Rela

2003

Other Studies

1 other study available for zonisamide and Peripheral Nervous System Diseases

ArticleYear
Pretreatment with Zonisamide Mitigates Oxaliplatin-Induced Toxicity in Rat DRG Neurons and DRG Neuron-Schwann Cell Co-Cultures.
    International journal of molecular sciences, 2022, Sep-01, Volume: 23, Issue:17

    Topics: Animals; Cells, Cultured; Coculture Techniques; Ganglia, Spinal; Mitogen-Activated Protein Kinase Ki

2022