zonisamide has been researched along with Neuralgia in 4 studies
Zonisamide: A benzisoxazole and sulfonamide derivative that acts as a CALCIUM CHANNEL blocker. It is used primarily as an adjunctive antiepileptic agent for the treatment of PARTIAL SEIZURES, with or without secondary generalization.
zonisamide : A 1,2-benzoxazole compound having a sulfamoylmethyl substituent at the 3-position.
Neuralgia: Intense or aching pain that occurs along the course or distribution of a peripheral or cranial nerve.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cellular mechanisms underlying neuropathic pain remain mostly elusive, and partial pain relief can be achieved in a limited number of patients by antidepressants, anticonvulsants topical anesthetics, and others." | 1.56 | Zonisamide ameliorates neuropathic pain partly by suppressing microglial activation in the spinal cord in a mouse model. ( Imagama, S; Inoue, T; Ishiguro, N; Ito, M; Kanbara, S; Kiryu-Seo, S; Kiyama, H; Konishi, H; Koshimizu, H; Masuda, A; Nakashima, H; Ohkawara, B; Ohno, K; Ota, K; Sayo, A; Tomita, H, 2020) |
| "Among them, 9a and 9b exhibited neuropathic pain alleviation effects in mechanical and cold allodynia induced in the SNL rat model." | 1.43 | Synthesis and T-type calcium channel-blocking effects of aryl(1,5-disubstituted-pyrazol-3-yl)methyl sulfonamides for neuropathic pain treatment. ( Chung, H; Keum, G; Kim, JH; Nam, G, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, JH | 1 |
| Keum, G | 1 |
| Chung, H | 1 |
| Nam, G | 1 |
| Koshimizu, H | 1 |
| Ohkawara, B | 1 |
| Nakashima, H | 1 |
| Ota, K | 1 |
| Kanbara, S | 1 |
| Inoue, T | 1 |
| Tomita, H | 1 |
| Sayo, A | 1 |
| Kiryu-Seo, S | 1 |
| Konishi, H | 1 |
| Ito, M | 1 |
| Masuda, A | 1 |
| Ishiguro, N | 1 |
| Imagama, S | 1 |
| Kiyama, H | 1 |
| Ohno, K | 1 |
| Moore, RA | 1 |
| Wiffen, PJ | 1 |
| Derry, S | 1 |
| Lunn, MP | 1 |
| Tanabe, M | 1 |
| Takeuchi, Y | 1 |
| Ono, H | 1 |
1 review available for zonisamide and Neuralgia
| Article | Year |
|---|---|
Zonisamide for neuropathic pain in adults.
Topics: Adult; Analgesics; Anticonvulsants; Diabetic Neuropathies; Female; Humans; Isoxazoles; Male; Middle | 2015 |
3 other studies available for zonisamide and Neuralgia
| Article | Year |
|---|---|
Synthesis and T-type calcium channel-blocking effects of aryl(1,5-disubstituted-pyrazol-3-yl)methyl sulfonamides for neuropathic pain treatment.
Topics: Animals; Calcium Channel Blockers; Calcium Channels, T-Type; Chemistry Techniques, Synthetic; Drug S | 2016 |
Zonisamide ameliorates neuropathic pain partly by suppressing microglial activation in the spinal cord in a mouse model.
Topics: Animals; Anticonvulsants; Cytokines; Disease Models, Animal; Hyperalgesia; Male; Mice; Microglia; Ne | 2020 |
The supraspinally mediated analgesic effects of zonisamide in mice after peripheral nerve injury are independent of the descending monoaminergic system.
Topics: Analgesics; Animals; Biogenic Monoamines; Chromatography, High Pressure Liquid; Disease Models, Anim | 2007 |