zonisamide has been researched along with Necrosis in 2 studies
Zonisamide: A benzisoxazole and sulfonamide derivative that acts as a CALCIUM CHANNEL blocker. It is used primarily as an adjunctive antiepileptic agent for the treatment of PARTIAL SEIZURES, with or without secondary generalization.
zonisamide : A 1,2-benzoxazole compound having a sulfamoylmethyl substituent at the 3-position.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| "When zonisamide (75 mg/kg) was administered i." | 1.29 | Zonisamide reduces hypoxic-ischemic brain damage in neonatal rats irrespective of its anticonvulsive effect. ( Hattori, H; Hayakawa, T; Higuchi, Y; Nigami, H, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Takami, Y | 1 |
| Izawa, T | 1 |
| Tanaka, M | 1 |
| Hatoya, S | 1 |
| Nabetani, T | 1 |
| Yamate, J | 1 |
| Kuwamura, M | 1 |
| Hayakawa, T | 1 |
| Higuchi, Y | 1 |
| Nigami, H | 1 |
| Hattori, H | 1 |
2 other studies available for zonisamide and Necrosis
| Article | Year |
|---|---|
Hepatocellular necrosis with prominent regenerative reactions in a zonisamide administrated dog.
Topics: Animals; Anticonvulsants; Chemical and Drug Induced Liver Injury; Dog Diseases; Dogs; Liver; Liver R | 2020 |
Zonisamide reduces hypoxic-ischemic brain damage in neonatal rats irrespective of its anticonvulsive effect.
Topics: Animals; Anticonvulsants; Body Temperature; Brain; Brain Ischemia; Electroencephalography; Hippocamp | 1994 |