zonisamide has been researched along with Migraine Disorders in 10 studies
Zonisamide: A benzisoxazole and sulfonamide derivative that acts as a CALCIUM CHANNEL blocker. It is used primarily as an adjunctive antiepileptic agent for the treatment of PARTIAL SEIZURES, with or without secondary generalization.
zonisamide : A 1,2-benzoxazole compound having a sulfamoylmethyl substituent at the 3-position.
Migraine Disorders: A class of disabling primary headache disorders, characterized by recurrent unilateral pulsatile headaches. The two major subtypes are common migraine (without aura) and classic migraine (with aura or neurological symptoms). (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Zonisamide is an antiepileptic drug used as adjunctive therapy for refractory partial seizures in adults." | 6.43 | Zonisamide: review of its use in epilepsy therapy. ( Zareba, G, 2005) |
| "Persistent migraine aura without infarction is a rare but debilitating condition." | 5.62 | Zonisamide as treatment option in persistent migraine aura. ( Broessner, G; Frank, F; Kaltseis, K, 2021) |
| "On the basis of six randomized controlled trials, zonisamide (ZNS) can be prescribed as add-on treatment in focal adulthood epilepsy in USA and Europe." | 4.85 | [Role of zonisamid in treating epilepsy, Parkinson disorders and other neurological diseases]. ( Janszky, J, 2009) |
| "The pathophysiology of pain in migraine is related to the activation of the trigeminovascular system by releasing vasoactive neuropeptides, the most important of which is calcitonin gene-related peptide (CGRP), which causes a neurogenic inflammation in the leptomeningeal vessels." | 2.84 | [Frequent episodic migraine and calcitonin gene-related peptide. Influence of treatment with topiramate and zonisamide on levels of the peptide]. ( Garcia-Estevez, DA; Pardo-Parrado, M; Silvarrey-Rodriguez, S, 2017) |
| "One hundred and twenty migraineurs who were refractory to topiramate were recruited." | 2.79 | Efficacy of zonisamide in migraineurs with nonresponse to topiramate. ( Chung, JY; Kim, M; Kim, MW, 2014) |
| "Zonisamide is an antiepileptic drug used as adjunctive therapy for refractory partial seizures in adults." | 2.43 | Zonisamide: review of its use in epilepsy therapy. ( Zareba, G, 2005) |
| "Persistent migraine aura without infarction is a rare but debilitating condition." | 1.62 | Zonisamide as treatment option in persistent migraine aura. ( Broessner, G; Frank, F; Kaltseis, K, 2021) |
| "Zonisamide is a relatively new sulfonamide derivative indicated for epilepsy and used off-label for migraines." | 1.42 | Zonisamide-induced angle closure and myopic shift. ( Weiler, DL, 2015) |
| "Zonisamide was well tolerated, only 4 (12%) patients reported transient and tolerable side effects." | 1.37 | Zonisamide for migraine prophylaxis in topiramate-intolerant patients: an observational study. ( Ciuffoli, A; Prosperini, L; Sette, G; Villani, V, 2011) |
| "Zonisamide is an antiepileptic drug with preliminary studies suggesting some efficacy in the adult headache population." | 1.33 | Zonisamide prophylaxis in refractory pediatric headache. ( Kring, D; Pakalnis, A, 2006) |
| "Zonisamide is a new antiepileptic drug with multiple mechanisms of action and a favourable pharmacokinetic profile." | 1.33 | Zonisamide for migraine prophylaxis in refractory patients. ( Ashkenazi, A; Benlifer, A; Korenblit, J; Silberstein, SD, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (40.00) | 29.6817 |
| 2010's | 5 (50.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kaltseis, K | 1 |
| Frank, F | 1 |
| Broessner, G | 1 |
| Garcia-Estevez, DA | 1 |
| Pardo-Parrado, M | 1 |
| Silvarrey-Rodriguez, S | 1 |
| Chung, JY | 1 |
| Kim, MW | 1 |
| Kim, M | 1 |
| Jion, YI | 1 |
| Raff, A | 1 |
| Grosberg, BM | 1 |
| Evans, RW | 1 |
| Weiler, DL | 1 |
| Janszky, J | 1 |
| Villani, V | 1 |
| Ciuffoli, A | 1 |
| Prosperini, L | 1 |
| Sette, G | 1 |
| Zareba, G | 1 |
| Pakalnis, A | 1 |
| Kring, D | 1 |
| Ashkenazi, A | 1 |
| Benlifer, A | 1 |
| Korenblit, J | 1 |
| Silberstein, SD | 1 |
3 reviews available for zonisamide and Migraine Disorders
| Article | Year |
|---|---|
The risk and management of kidney stones from the use of topiramate and zonisamide in migraine and idiopathic intracranial hypertension.
Topics: Adult; Anticonvulsants; Female; Fructose; Humans; Isoxazoles; Kidney Calculi; Migraine Disorders; Ps | 2015 |
[Role of zonisamid in treating epilepsy, Parkinson disorders and other neurological diseases].
Topics: Anticonvulsants; Bipolar Disorder; Calcium Channels, T-Type; Cholinergic Agents; Dopamine Agents; Dy | 2009 |
Zonisamide: review of its use in epilepsy therapy.
Topics: Animals; Anticonvulsants; Biological Availability; Child; Child, Preschool; Drug Interactions; Epile | 2005 |
2 trials available for zonisamide and Migraine Disorders
| Article | Year |
|---|---|
[Frequent episodic migraine and calcitonin gene-related peptide. Influence of treatment with topiramate and zonisamide on levels of the peptide].
Topics: Adult; Aged; Calcitonin Gene-Related Peptide; Female; Fructose; Humans; Isoxazoles; Male; Middle Age | 2017 |
Efficacy of zonisamide in migraineurs with nonresponse to topiramate.
Topics: Adult; Female; Fructose; Headache; Humans; Isoxazoles; Male; Middle Aged; Migraine Disorders; Parest | 2014 |
5 other studies available for zonisamide and Migraine Disorders
| Article | Year |
|---|---|
Zonisamide as treatment option in persistent migraine aura.
Topics: Adolescent; Drug-Related Side Effects and Adverse Reactions; Epilepsy; Female; Humans; Migraine Diso | 2021 |
Zonisamide-induced angle closure and myopic shift.
Topics: Acute Disease; Adult; Anticonvulsants; Female; Glaucoma, Angle-Closure; Gonioscopy; Humans; Intraocu | 2015 |
Zonisamide for migraine prophylaxis in topiramate-intolerant patients: an observational study.
Topics: Adult; Anticonvulsants; Female; Follow-Up Studies; Fructose; Humans; Incidence; Isoxazoles; Middle A | 2011 |
Zonisamide prophylaxis in refractory pediatric headache.
Topics: Adolescent; Anticonvulsants; Child; Drug Resistance; Female; Humans; Isoxazoles; Male; Medical Recor | 2006 |
Zonisamide for migraine prophylaxis in refractory patients.
Topics: Adult; Anticonvulsants; Drug Resistance; Female; Humans; Isoxazoles; Male; Middle Aged; Migraine Dis | 2006 |