zonisamide has been researched along with Mental Disorders in 9 studies
Zonisamide: A benzisoxazole and sulfonamide derivative that acts as a CALCIUM CHANNEL blocker. It is used primarily as an adjunctive antiepileptic agent for the treatment of PARTIAL SEIZURES, with or without secondary generalization.
zonisamide : A 1,2-benzoxazole compound having a sulfamoylmethyl substituent at the 3-position.
Mental Disorders: Psychiatric illness or diseases manifested by breakdowns in the adaptational process expressed primarily as abnormalities of thought, feeling, and behavior producing either distress or impairment of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Zonisamide is a broad spectrum antiepileptic drug with multiple mechanisms of action which has been recently approved in the US and Europe as an adjunctive therapy for refractory partial seizures in adults." | 6.47 | Drug safety evaluation of zonisamide for the treatment of epilepsy. ( Cincotta, M; Tramacere, L; Zaccara, G, 2011) |
| " Since psychiatric adverse effects, including mania, psychosis, and suicidal ideation, have been associated with its use, it was suggested that the presence of antecedent psychiatric disorders is an important factor associated with the discontinuation of zonisamide therapy in patients with epilepsy." | 5.39 | Psychiatric adverse effects of zonisamide in patients with epilepsy and mental disorder comorbidities. ( Cavanna, AE; Seri, S, 2013) |
| "Zonisamide is a broad spectrum antiepileptic drug with multiple mechanisms of action which has been recently approved in the US and Europe as an adjunctive therapy for refractory partial seizures in adults." | 2.47 | Drug safety evaluation of zonisamide for the treatment of epilepsy. ( Cincotta, M; Tramacere, L; Zaccara, G, 2011) |
| "A review of the pharmacokinetics, pharmacodynamics, evidence for efficacy in different seizure types and non-seizure conditions, adverse effects, and tolerability of ZNS is presented." | 2.44 | Zonisamide: review of pharmacology, clinical efficacy, tolerability, and safety. ( Kaleyias, J; Kothare, SV, 2008) |
| " Since psychiatric adverse effects, including mania, psychosis, and suicidal ideation, have been associated with its use, it was suggested that the presence of antecedent psychiatric disorders is an important factor associated with the discontinuation of zonisamide therapy in patients with epilepsy." | 1.39 | Psychiatric adverse effects of zonisamide in patients with epilepsy and mental disorder comorbidities. ( Cavanna, AE; Seri, S, 2013) |
| "Zonisamide (ZNS) is an antiepileptic drug (AED) that has been associated with psychiatric adverse events (PAE) and cognitive adverse events (CAE); controlled studies evaluating these adverse events are limited." | 1.36 | Zonisamide discontinuation due to psychiatric and cognitive adverse events: a case-control study. ( Beniak, TE; Birnbaum, AK; Leppik, IE; Marino, SE; Walczak, TS; White, JR, 2010) |
| "Zonisamide safety was evaluated based on a postmarketing surveillance study of patients treated for 1-3 years." | 1.34 | Erratum to "Safety of zonisamide therapy: prospective follow-up survey.". ( Ohtahara, S; Yamatogi, Y, 2007) |
| "Zonisamide safety was evaluated based on a postmarketing surveillance study of patients treated for 1-3 years." | 1.32 | Safety of zonisamide therapy: prospective follow-up survey. ( Ohtahara, S; Yamatogi, Y, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 4 (44.44) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Janković, SM | 1 |
| Cavanna, AE | 1 |
| Seri, S | 1 |
| White, JR | 1 |
| Walczak, TS | 1 |
| Marino, SE | 1 |
| Beniak, TE | 1 |
| Leppik, IE | 1 |
| Birnbaum, AK | 1 |
| Zaccara, G | 1 |
| Tramacere, L | 1 |
| Cincotta, M | 1 |
| Lim, J | 1 |
| Ko, YH | 1 |
| Joe, SH | 1 |
| Han, C | 1 |
| Lee, MS | 1 |
| Yang, J | 1 |
| Ohtahara, S | 2 |
| Yamatogi, Y | 2 |
| Kothare, SV | 1 |
| Kaleyias, J | 1 |
| Ozawa, H | 1 |
| Sasaki, M | 1 |
| Sugai, K | 1 |
| Yano, H | 1 |
3 reviews available for zonisamide and Mental Disorders
| Article | Year |
|---|---|
Evaluation of zonisamide for the treatment of focal epilepsy: a review of pharmacokinetics, clinical efficacy and adverse effects.
Topics: Anticonvulsants; Clinical Trials as Topic; Drug-Related Side Effects and Adverse Reactions; Epilepsi | 2020 |
Drug safety evaluation of zonisamide for the treatment of epilepsy.
Topics: Animals; Drug-Related Side Effects and Adverse Reactions; Epilepsy; Humans; Isoxazoles; Kidney Calcu | 2011 |
Zonisamide: review of pharmacology, clinical efficacy, tolerability, and safety.
Topics: Analgesics, Non-Narcotic; Anticonvulsants; Brain Diseases; Clinical Trials as Topic; Epilepsy; Human | 2008 |
6 other studies available for zonisamide and Mental Disorders
| Article | Year |
|---|---|
Psychiatric adverse effects of zonisamide in patients with epilepsy and mental disorder comorbidities.
Topics: Adolescent; Adult; Anticonvulsants; Child; Comorbidity; Electroencephalography; Epilepsy; Female; Hu | 2013 |
Zonisamide discontinuation due to psychiatric and cognitive adverse events: a case-control study.
Topics: Adult; Anticonvulsants; Case-Control Studies; Cognition Disorders; Epilepsy; Female; Humans; Isoxazo | 2010 |
Zonisamide produces weight loss in psychotropic drug-treated psychiatric outpatients.
Topics: Adult; Female; Humans; Isoxazoles; Male; Mental Disorders; Middle Aged; Outpatients; Overweight; Psy | 2011 |
Safety of zonisamide therapy: prospective follow-up survey.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Age Factors; Aged; Anticonvulsants; Child; Child, Pr | 2004 |
Erratum to "Safety of zonisamide therapy: prospective follow-up survey.".
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Age Factors; Aged; Anticonvulsants; Child; Child, Pr | 2007 |
[A case of behavior disorder with gait and sleep disturbances induced by zonisamide].
Topics: Anticonvulsants; Child; Female; Gait; Humans; Isoxazoles; Mental Disorders; Sleep Wake Disorders; Zo | 1995 |