Page last updated: 2024-11-05

zonisamide and Kidney Calculi

zonisamide has been researched along with Kidney Calculi in 8 studies

Zonisamide: A benzisoxazole and sulfonamide derivative that acts as a CALCIUM CHANNEL blocker. It is used primarily as an adjunctive antiepileptic agent for the treatment of PARTIAL SEIZURES, with or without secondary generalization.
zonisamide : A 1,2-benzoxazole compound having a sulfamoylmethyl substituent at the 3-position.

Kidney Calculi: Stones in the KIDNEY, usually formed in the urine-collecting area of the kidney (KIDNEY PELVIS). Their sizes vary and most contains CALCIUM OXALATE.

Research Excerpts

ExcerptRelevanceReference
"To determine the prevalence of renal calculi in patients treated with zonisamide during randomized, controlled and open-label clinical trials, and from post-marketing surveillance data."6.73Zonisamide and renal calculi in patients with epilepsy: how big an issue? ( Wroe, S, 2007)
"Zonisamide is a broad spectrum antiepileptic drug with multiple mechanisms of action which has been recently approved in the US and Europe as an adjunctive therapy for refractory partial seizures in adults."6.47Drug safety evaluation of zonisamide for the treatment of epilepsy. ( Cincotta, M; Tramacere, L; Zaccara, G, 2011)
"Zonisamide (ZNS) was partially effective for the former seizures, and propranolol for the latter."5.31[Urolithiasis induced by combined ACTH and zonisamide treatment in a patient with startle induced epilepsy]. ( Hayashi, K; Jo, K; Katsumori, H; Nagafuchi, H; Oguni, H; Osawa, M; Saito, Y; Yanagaki, S, 2002)
"To determine the prevalence of renal calculi in patients treated with zonisamide during randomized, controlled and open-label clinical trials, and from post-marketing surveillance data."2.73Zonisamide and renal calculi in patients with epilepsy: how big an issue? ( Wroe, S, 2007)
"Zonisamide is a broad spectrum antiepileptic drug with multiple mechanisms of action which has been recently approved in the US and Europe as an adjunctive therapy for refractory partial seizures in adults."2.47Drug safety evaluation of zonisamide for the treatment of epilepsy. ( Cincotta, M; Tramacere, L; Zaccara, G, 2011)
"Zonisamide is an antiepilepsy drug (AED) with both sodium and calcium channel-blocking properties."2.42Review of United States and European clinical trials of zonisamide in the treatment of refractory partial-onset seizures. ( Faught, E, 2004)
"Zonisamide (ZNS) was partially effective for the former seizures, and propranolol for the latter."1.31[Urolithiasis induced by combined ACTH and zonisamide treatment in a patient with startle induced epilepsy]. ( Hayashi, K; Jo, K; Katsumori, H; Nagafuchi, H; Oguni, H; Osawa, M; Saito, Y; Yanagaki, S, 2002)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's0 (0.00)18.2507
2000's5 (62.50)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jion, YI1
Raff, A1
Grosberg, BM1
Evans, RW1
Zaccara, G1
Tramacere, L1
Cincotta, M1
Saito, Y1
Yanagaki, S1
Oguni, H1
Hayashi, K1
Katsumori, H1
Nagafuchi, H1
Jo, K1
Osawa, M1
Faught, E1
Richards, KC1
Smith, MC1
Verma, A1
Wroe, S1
Kubota, M1
Nishi-Nagase, M1
Sakakihara, Y1
Noma, S1
Nakamoto, M1
Kawaguchi, H1
Yanagisawa, M1
Sander, JW1
Hart, YM1
Duncan, JS1
Shorvon, SD1

Reviews

3 reviews available for zonisamide and Kidney Calculi

ArticleYear
The risk and management of kidney stones from the use of topiramate and zonisamide in migraine and idiopathic intracranial hypertension.
    Headache, 2015, Volume: 55, Issue:1

    Topics: Adult; Anticonvulsants; Female; Fructose; Humans; Isoxazoles; Kidney Calculi; Migraine Disorders; Ps

2015
Drug safety evaluation of zonisamide for the treatment of epilepsy.
    Expert opinion on drug safety, 2011, Volume: 10, Issue:4

    Topics: Animals; Drug-Related Side Effects and Adverse Reactions; Epilepsy; Humans; Isoxazoles; Kidney Calcu

2011
Review of United States and European clinical trials of zonisamide in the treatment of refractory partial-onset seizures.
    Seizure, 2004, Volume: 13 Suppl 1

    Topics: Anticonvulsants; Clinical Trials as Topic; Epilepsies, Partial; Europe; Humans; Isoxazoles; Kidney C

2004

Trials

1 trial available for zonisamide and Kidney Calculi

ArticleYear
Zonisamide and renal calculi in patients with epilepsy: how big an issue?
    Current medical research and opinion, 2007, Volume: 23, Issue:8

    Topics: Adolescent; Adult; Anticonvulsants; Child; Double-Blind Method; Epilepsy; Female; Fructose; Humans;

2007

Other Studies

4 other studies available for zonisamide and Kidney Calculi

ArticleYear
[Urolithiasis induced by combined ACTH and zonisamide treatment in a patient with startle induced epilepsy].
    No to hattatsu = Brain and development, 2002, Volume: 34, Issue:5

    Topics: Adrenocorticotropic Hormone; Anticonvulsants; Child, Preschool; Drug Therapy, Combination; Epilepsy;

2002
Continued use of zonisamide following development of renal calculi.
    Neurology, 2005, Feb-22, Volume: 64, Issue:4

    Topics: Adult; Anticonvulsants; Calcium Citrate; Carbamazepine; Drug Therapy, Combination; Fluid Therapy; Hu

2005
Zonisamide - induced urinary lithiasis in patients with intractable epilepsy.
    Brain & development, 2000, Volume: 22, Issue:4

    Topics: Adolescent; Anticonvulsants; Child; Female; Humans; Hydronephrosis; Isoxazoles; Kidney Calculi; Male

2000
Zonisamide usage.
    Neurology, 1989, Volume: 39, Issue:5

    Topics: Epilepsies, Myoclonic; Humans; Isoxazoles; Kidney Calculi; Oxazoles; Zonisamide

1989